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METABOLIC CALCINOSIS IN THE NEWBORN: Report of a Case

METABOLIC CALCINOSIS IN THE NEWBORN: Report of a Case Abstract CASES of cutaneous calcinosis have been described in the literature often enough so that they can by no means be considered rare. However, calcinosis in a newborn infant has been seen on relatively few occasions. Accordingly, our recent observations concerning an infant whose illness began at the age of 2 weeks seemed worthy of publication. Before presenting the report of our case, we shall summarize the important features of the disease as they have been recorded in the literature. CLASSIFICATION Maloney and Bloom1 divided calcinosis into local and general types, the former being a purely local disease denoting calcification in tumors, cysts, and hematomas, and the latter resulting from a widespread disturbance within the body. The etiologic classification presented by Peters and co-workers2 divided the cases into four categories: (1) those in which the calcification results from known disturbances of calcium or phosphorus metabolism; (2) those in References 1. Maloney, E. R., and Bloom, D.: Cutaneous Calcinosis: Report of Case , Arch. Dermat. & Syph. 23:245 ( (Feb.) ) 1931. 2. Peters, J. H.; Horn, R. H., and Greeman, L.: Idiopathic Calcinosis Universalis Cutis Without Disability , Ann. Int. Med. 32:138 ( (Jan.) ) 1950. 3. Nunez, B. E., and Arthur, P. S.: Calcinosis: Report of 2 Cases , M. Ann. District of Columbia 12:301 ( (Aug.) ) 1943. 4. Rothstein, J. L., and Welt, S.: Calcinosis Universalis and Calcinosis Circumscripta in Infancy and in Childhood: 3 Cases of Calcinosis Universalis, with Review of Literature , Am. J. Dis. Child. 52:368 ( (Aug.) ) 1936. 5. Moggi, D., cited by Rothstein and Welt.3b 6. Hein, B. J.: Calcinosis Universalis , Arch. Surg. 26:389 ( (March) ) 1933. 7. Tyson, R. M., and Weiss, S.: Calcinosis Interstitialis Universalis: Report of Case with Improvement , Arch. Pediat. 53:550 ( (Aug.) ) 1936. 8. Staub, V., cited by Barr, D. P.: Pathological Calcification , Physiol. Rev. 12:593 ( (Oct.) ) 1932. 9. Costello, M. J.: Cutaneous Calcinosis , New York J. Med. 35:1266 ( (Dec. 15) ) 1935. 10. Thannhauser, S. J., cited by Barr, D. P.: Pathological Calcification , Physiol. Rev. 12:593 ( (Oct.) ) 1932. 11. Tisdall, F. F., and Erb, I. H.: Report of 2 Cases with Unusual Calcareous Deposits , Am. J. Dis. Child. 27:28 ( (Jan.) ) 1924. 12. Morse, J. L.: Calcification of Skin in Child , Am. J. Dis. Child. 22:412 ( (Oct.) ) 1921. 13. Weidman, F. D., and Shaffer, L. W.: Calcification of the Skin, Including the Epiderm in Connection with Extensive Bone Resorption , Arch. Dermat. & Syph. 14:503 ( (Nov.) ) 1926. 14. Bauer, W.; Marble, A., and Bennett, G. A.: Further Studies in Case of Calcification of Subcutaneous Tissue ("Calcinosis Universalis") in Child , Am. J. M. Sc. 182:237 ( (Aug.) ) 1931. 15. Steinitz, H., cited by Rothstein and Welt.3b 16. Swanson, W. W.; Forster, W. G., and Iob, L. V.: Calcinosis Circumscripta , Am. J. Dis. Child. 45:590 ( (March) ) 1933. 17. Bloxsom, A., and Johnston, R. A.: Calcinosis Universalis with Unusual Features , Am. J. Dis. Child. 56:103 ( (July) ) 1938. 18. Epstein, E.: Idiopathic Calcinosis Cutis: A Review, with a Report of 2 Cases , Arch. Dermat. & Syph. 34:367 ( (Sept.) ) 1936. 19. Craig, J., and Lyall, A.: A Case of Calcinosis Universalis, and a Suggested Method of Treatment , Brit. J. Child. Dis. 28:29 ( (Jan.) -March) 1931. 20. Brooks, W. D. W.: Calcinosis , Quart. J. Med. 3:293 ( (July) ) 1934. 21. Jacobowitz, H., cited by Rothstein and Welt.3b 22. Kennedy, R. L. J.: Calcinosis: Case , Proc. Staff Meet., Mayo Clin. 7:329 ( (June 8) ) 1932. 23. Zarfl, M., cited by Rothstein and Welt.3b 24. This case was referred to us for study by Dr. Joseph Doll, of the Pediatric Department, Pawtucket Memorial Hospital. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology & Syphilology American Medical Association

METABOLIC CALCINOSIS IN THE NEWBORN: Report of a Case

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References (22)

Publisher
American Medical Association
Copyright
Copyright © 1953 American Medical Association. All Rights Reserved.
ISSN
0096-5979
DOI
10.1001/archderm.1953.01540120056009
Publisher site
See Article on Publisher Site

Abstract

Abstract CASES of cutaneous calcinosis have been described in the literature often enough so that they can by no means be considered rare. However, calcinosis in a newborn infant has been seen on relatively few occasions. Accordingly, our recent observations concerning an infant whose illness began at the age of 2 weeks seemed worthy of publication. Before presenting the report of our case, we shall summarize the important features of the disease as they have been recorded in the literature. CLASSIFICATION Maloney and Bloom1 divided calcinosis into local and general types, the former being a purely local disease denoting calcification in tumors, cysts, and hematomas, and the latter resulting from a widespread disturbance within the body. The etiologic classification presented by Peters and co-workers2 divided the cases into four categories: (1) those in which the calcification results from known disturbances of calcium or phosphorus metabolism; (2) those in References 1. Maloney, E. R., and Bloom, D.: Cutaneous Calcinosis: Report of Case , Arch. Dermat. & Syph. 23:245 ( (Feb.) ) 1931. 2. Peters, J. H.; Horn, R. H., and Greeman, L.: Idiopathic Calcinosis Universalis Cutis Without Disability , Ann. Int. Med. 32:138 ( (Jan.) ) 1950. 3. Nunez, B. E., and Arthur, P. S.: Calcinosis: Report of 2 Cases , M. Ann. District of Columbia 12:301 ( (Aug.) ) 1943. 4. Rothstein, J. L., and Welt, S.: Calcinosis Universalis and Calcinosis Circumscripta in Infancy and in Childhood: 3 Cases of Calcinosis Universalis, with Review of Literature , Am. J. Dis. Child. 52:368 ( (Aug.) ) 1936. 5. Moggi, D., cited by Rothstein and Welt.3b 6. Hein, B. J.: Calcinosis Universalis , Arch. Surg. 26:389 ( (March) ) 1933. 7. Tyson, R. M., and Weiss, S.: Calcinosis Interstitialis Universalis: Report of Case with Improvement , Arch. Pediat. 53:550 ( (Aug.) ) 1936. 8. Staub, V., cited by Barr, D. P.: Pathological Calcification , Physiol. Rev. 12:593 ( (Oct.) ) 1932. 9. Costello, M. J.: Cutaneous Calcinosis , New York J. Med. 35:1266 ( (Dec. 15) ) 1935. 10. Thannhauser, S. J., cited by Barr, D. P.: Pathological Calcification , Physiol. Rev. 12:593 ( (Oct.) ) 1932. 11. Tisdall, F. F., and Erb, I. H.: Report of 2 Cases with Unusual Calcareous Deposits , Am. J. Dis. Child. 27:28 ( (Jan.) ) 1924. 12. Morse, J. L.: Calcification of Skin in Child , Am. J. Dis. Child. 22:412 ( (Oct.) ) 1921. 13. Weidman, F. D., and Shaffer, L. W.: Calcification of the Skin, Including the Epiderm in Connection with Extensive Bone Resorption , Arch. Dermat. & Syph. 14:503 ( (Nov.) ) 1926. 14. Bauer, W.; Marble, A., and Bennett, G. A.: Further Studies in Case of Calcification of Subcutaneous Tissue ("Calcinosis Universalis") in Child , Am. J. M. Sc. 182:237 ( (Aug.) ) 1931. 15. Steinitz, H., cited by Rothstein and Welt.3b 16. Swanson, W. W.; Forster, W. G., and Iob, L. V.: Calcinosis Circumscripta , Am. J. Dis. Child. 45:590 ( (March) ) 1933. 17. Bloxsom, A., and Johnston, R. A.: Calcinosis Universalis with Unusual Features , Am. J. Dis. Child. 56:103 ( (July) ) 1938. 18. Epstein, E.: Idiopathic Calcinosis Cutis: A Review, with a Report of 2 Cases , Arch. Dermat. & Syph. 34:367 ( (Sept.) ) 1936. 19. Craig, J., and Lyall, A.: A Case of Calcinosis Universalis, and a Suggested Method of Treatment , Brit. J. Child. Dis. 28:29 ( (Jan.) -March) 1931. 20. Brooks, W. D. W.: Calcinosis , Quart. J. Med. 3:293 ( (July) ) 1934. 21. Jacobowitz, H., cited by Rothstein and Welt.3b 22. Kennedy, R. L. J.: Calcinosis: Case , Proc. Staff Meet., Mayo Clin. 7:329 ( (June 8) ) 1932. 23. Zarfl, M., cited by Rothstein and Welt.3b 24. This case was referred to us for study by Dr. Joseph Doll, of the Pediatric Department, Pawtucket Memorial Hospital.

Journal

A.M.A. Archives of Dermatology & SyphilologyAmerican Medical Association

Published: Dec 1, 1953

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