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MELKERSSON'S SYNDROME

MELKERSSON'S SYNDROME Abstract IN 1928 Melkersson1 described an unusual syndrome consisting of recurrent peripheral facial paralysis associated with chronic edema of the face and lips. Inasmuch as the cause and the pathologic changes in this puzzling condition remain uncertain, the experience with an additional case is deemed worthy of reporting. According to Kettel,2 Melkersson's syndrome is recognized at the present time as a triad of findings: (a) peripheral facial paralysis, (b) chronic angioneurotic facial edema and (c) lingua plicata. The peripheral facial paralysis in this syndrome is indistinguishable from Bell's palsy. The angioneurotic edema is chronic and is most often localized to the lips, usually the upper lip. The deeply furrowed tongue, or lingua plicata, was added to the syndrome by Rosenthal3 in 1931. Kettel has pointed out that the disease frequently begins in childhood or youth, in the majority of cases before the eighteenth year. Swelling of the face may occur at References 1. Melkersson, E.: Hygiea 90:737, 1928. 2. Kettel, K.: Melkersson's Syndrome: Report of Five Cases, with Special Reference to Pathologic Observations , Arch. Otolaryng. 46:341 ( (Sept.) ) 1947.Crossref 3. Rosenthal, C.: Ztschr. f. d. ges. Neurol. u. Psychiat. 131:475, 1931.Crossref 4. New, G. B., and Kirch, W. A.: Permanent Enlargement of Lips and Face Secondary to Recurring Swellings and Associated with Facial Paralysis: Clinical Entity , J. A. M. A. 1230 ( (April 22) ) 1933. 5. Hilger, J. A.: Laryngoscope 59:228 ( (March) ) 1949. 6. Conway, H.: Surg., Gynec. & Obst. 66:1024 ( (June) ) 1938. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

MELKERSSON'S SYNDROME

McGOVERN, FRANCIS H.
Archives of Otolaryngology , Volume 51 (3) – Mar 1, 1950
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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1950 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1950.00700020393008
Publisher site
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Abstract

Abstract IN 1928 Melkersson1 described an unusual syndrome consisting of recurrent peripheral facial paralysis associated with chronic edema of the face and lips. Inasmuch as the cause and the pathologic changes in this puzzling condition remain uncertain, the experience with an additional case is deemed worthy of reporting. According to Kettel,2 Melkersson's syndrome is recognized at the present time as a triad of findings: (a) peripheral facial paralysis, (b) chronic angioneurotic facial edema and (c) lingua plicata. The peripheral facial paralysis in this syndrome is indistinguishable from Bell's palsy. The angioneurotic edema is chronic and is most often localized to the lips, usually the upper lip. The deeply furrowed tongue, or lingua plicata, was added to the syndrome by Rosenthal3 in 1931. Kettel has pointed out that the disease frequently begins in childhood or youth, in the majority of cases before the eighteenth year. Swelling of the face may occur at References 1. Melkersson, E.: Hygiea 90:737, 1928. 2. Kettel, K.: Melkersson's Syndrome: Report of Five Cases, with Special Reference to Pathologic Observations , Arch. Otolaryng. 46:341 ( (Sept.) ) 1947.Crossref 3. Rosenthal, C.: Ztschr. f. d. ges. Neurol. u. Psychiat. 131:475, 1931.Crossref 4. New, G. B., and Kirch, W. A.: Permanent Enlargement of Lips and Face Secondary to Recurring Swellings and Associated with Facial Paralysis: Clinical Entity , J. A. M. A. 1230 ( (April 22) ) 1933. 5. Hilger, J. A.: Laryngoscope 59:228 ( (March) ) 1949. 6. Conway, H.: Surg., Gynec. & Obst. 66:1024 ( (June) ) 1938.

Journal

Archives of Otolaryngology – American Medical Association

Published: Mar 1, 1950

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