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Melkersson - Rosenthal Syndrome

Melkersson - Rosenthal Syndrome Abstract The Melkersson-Rosenthal syndrome is an unusual condition which, except for a few isolated reports in otolaryngologic journals, is rarely described in American medical literature. It comprises a triad consisting of recurrent facial paralysis, intermittent facial edema which subsequently becomes permanent, and lingua plicata. The only case of this condition in an American dermatologic journal was reported by Klaus and Brunsting,1 but many more reports have appeared in European journals. Four cases were presented at the Eleventh International Congress of Dermatology.2 We have observed 2 patients having this condition and believe this report may further an awareness of the syndrome. Case Reports Case 1.— A 63-year-old woman had swelling of the lower lip for the past 6 months, and although the severity had fluctuated, no significant improvement had occurred. There was no evidence of dental involvement. About 10 years previously she had noted facial paralysis.On examination, there was a References 1. Klaus, S. N., and Brunsting, L. A.: Melkersson's Syndrome , Proc. Mayo Clin. 34:365, 1959. 2. Lodin, A., and Gentele, H.: One Hundred Clinical Cases presented at the Eleventh International Congress of Dermatology at Stockholm , (July 30) , 1957. 3. Ekbom, K. A.: Plicated Tongue in Melkersson's Syndrome and in Paralysis of the Facial Nerve , Acta Med. Scand. 138:42, 1950.Crossref 4. Miescher, G.: Über essentielle Granulomatose Makrocheilie (Cheilitis granulomatosa) , Dermatologica 91:57, 1945.Crossref 5. Findlay, G. H.: Idiopathic Enlargements of the Lips , Brit. J. Derm. 66:129, 1954.Crossref 6. Aderhold, K.; Kronke, E., and Pawlik, H. J.: Melkersson-Rosenthal Syndrome mit Megacolon congenitum , Deutsch. Gesundh. 12:513, 1957. 7. Panebianco, G., and Manara, E.: La sindrome di Melkersson-Rosenthal: Observazione di due case , Otorinolaring. Ital. 25:493, 1957. 8. Stumpf, W., and Schuppener, H. J.: Das Melkersson-Rosenthal Syndrom: Untersuchungen zur Psychogenese: Klin. Wschr. 35:882 ( (Sept.) ) 1957.Crossref 9. Kettel, K.: Melkersson's Syndrome: Report of 5 Cases with Special Reference to the Pathologic Observations , Arch. Otolaryng. 46:341 ( (Sept.) ) 1947.Crossref 10. Hilger, J. A.: The Nature of Bell's Palsy , Laryngoscope 59:228 ( (March) ) 1949. 11. New, G. B., and Kirch, W. A.: Permanent Enlargement of the Lips and Face Secondary to Recurring Swellings and Associated with Facial Paralysis: A Clinical Entity , J.A.M.A. 100:1230 ( (April 22) ) 1933.Crossref 12. Schuppener, H. J.: Zum Melkersson-Rosenthal Syndrom , Deutsch. Gesundh. 11:1958, 1956. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Melkersson - Rosenthal Syndrome

Archives of Dermatology , Volume 84 (5) – Nov 1, 1961

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Publisher
American Medical Association
Copyright
Copyright © 1961 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1961.01580170092012
Publisher site
See Article on Publisher Site

Abstract

Abstract The Melkersson-Rosenthal syndrome is an unusual condition which, except for a few isolated reports in otolaryngologic journals, is rarely described in American medical literature. It comprises a triad consisting of recurrent facial paralysis, intermittent facial edema which subsequently becomes permanent, and lingua plicata. The only case of this condition in an American dermatologic journal was reported by Klaus and Brunsting,1 but many more reports have appeared in European journals. Four cases were presented at the Eleventh International Congress of Dermatology.2 We have observed 2 patients having this condition and believe this report may further an awareness of the syndrome. Case Reports Case 1.— A 63-year-old woman had swelling of the lower lip for the past 6 months, and although the severity had fluctuated, no significant improvement had occurred. There was no evidence of dental involvement. About 10 years previously she had noted facial paralysis.On examination, there was a References 1. Klaus, S. N., and Brunsting, L. A.: Melkersson's Syndrome , Proc. Mayo Clin. 34:365, 1959. 2. Lodin, A., and Gentele, H.: One Hundred Clinical Cases presented at the Eleventh International Congress of Dermatology at Stockholm , (July 30) , 1957. 3. Ekbom, K. A.: Plicated Tongue in Melkersson's Syndrome and in Paralysis of the Facial Nerve , Acta Med. Scand. 138:42, 1950.Crossref 4. Miescher, G.: Über essentielle Granulomatose Makrocheilie (Cheilitis granulomatosa) , Dermatologica 91:57, 1945.Crossref 5. Findlay, G. H.: Idiopathic Enlargements of the Lips , Brit. J. Derm. 66:129, 1954.Crossref 6. Aderhold, K.; Kronke, E., and Pawlik, H. J.: Melkersson-Rosenthal Syndrome mit Megacolon congenitum , Deutsch. Gesundh. 12:513, 1957. 7. Panebianco, G., and Manara, E.: La sindrome di Melkersson-Rosenthal: Observazione di due case , Otorinolaring. Ital. 25:493, 1957. 8. Stumpf, W., and Schuppener, H. J.: Das Melkersson-Rosenthal Syndrom: Untersuchungen zur Psychogenese: Klin. Wschr. 35:882 ( (Sept.) ) 1957.Crossref 9. Kettel, K.: Melkersson's Syndrome: Report of 5 Cases with Special Reference to the Pathologic Observations , Arch. Otolaryng. 46:341 ( (Sept.) ) 1947.Crossref 10. Hilger, J. A.: The Nature of Bell's Palsy , Laryngoscope 59:228 ( (March) ) 1949. 11. New, G. B., and Kirch, W. A.: Permanent Enlargement of the Lips and Face Secondary to Recurring Swellings and Associated with Facial Paralysis: A Clinical Entity , J.A.M.A. 100:1230 ( (April 22) ) 1933.Crossref 12. Schuppener, H. J.: Zum Melkersson-Rosenthal Syndrom , Deutsch. Gesundh. 11:1958, 1956.

Journal

Archives of DermatologyAmerican Medical Association

Published: Nov 1, 1961

References