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Melanoma Resembling Spindle and Epithelioid Cell Nevus: Report of Three Cases

Melanoma Resembling Spindle and Epithelioid Cell Nevus: Report of Three Cases Abstract Three cases of malignant melanoma resembling spindle and epithelioid cell nevus histologically are presented. Lesions having histologic features of spindle and epithelioid cell nevus (Spitz nevus or juvenile melanoma) at or after puberty should be regarded with caution, particularly when they are heavily melanized. Such lesions are in a histologic "gray zone" and may be malignant. (Arch Dermatol 115:1416-1420, 1979) References 1. Spitz S: Spindle and epithelioid cell nevi in the adult . Am J Pathol 25:591-609, 1948. 2. Echevarria R, Ackerman LV: Spindle and epithelioid cell nevi in the adult . Cancer 20:175-189, 1967.Crossref 3. Kernen JA, Ackerman LV: Spindle cell nevi and epithelioid cell nevi (so-called juvenile melanomas) in children and adults: A clinicopathological study of 27 cases . Cancer 13:612-625, 1960.Crossref 4. Helwig B: Malignant melanoma in children , in Freitag SB, Culhane DL, Demec JC (eds): Neoplasms of the Skin and Malignant Melanoma . Chicago, Year Book Medical Publishers Inc, 1976, p 19. 5. Paniago-Pereira C, Maize JC, Ackerman AB: Nevus of large spindle and/or epithelioid cells (Spitz's nevus) . Arch Dermatol 114:1811-1823, 1978.Crossref 6. Lever WF, Schaumburg-Lever G: Histopathology of the Skin . Philadelphia, JB Lippincott Co, 1975, p 671. 7. Okun M, Edelstein L: Gross and Microscopic Pathology of the Skin . Boston, Dermatopathology Foundation Press, 1976, vol 2, pp 958, 985. 8. McGovern V: Malignant Melanoma: Clinical and Histologic Diagnosis . New York, John Wiley & Sons Inc, 1976, p 149. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Melanoma Resembling Spindle and Epithelioid Cell Nevus: Report of Three Cases

Archives of Dermatology , Volume 115 (12) – Dec 1, 1979

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Publisher
American Medical Association
Copyright
Copyright © 1979 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1979.04010120014007
Publisher site
See Article on Publisher Site

Abstract

Abstract Three cases of malignant melanoma resembling spindle and epithelioid cell nevus histologically are presented. Lesions having histologic features of spindle and epithelioid cell nevus (Spitz nevus or juvenile melanoma) at or after puberty should be regarded with caution, particularly when they are heavily melanized. Such lesions are in a histologic "gray zone" and may be malignant. (Arch Dermatol 115:1416-1420, 1979) References 1. Spitz S: Spindle and epithelioid cell nevi in the adult . Am J Pathol 25:591-609, 1948. 2. Echevarria R, Ackerman LV: Spindle and epithelioid cell nevi in the adult . Cancer 20:175-189, 1967.Crossref 3. Kernen JA, Ackerman LV: Spindle cell nevi and epithelioid cell nevi (so-called juvenile melanomas) in children and adults: A clinicopathological study of 27 cases . Cancer 13:612-625, 1960.Crossref 4. Helwig B: Malignant melanoma in children , in Freitag SB, Culhane DL, Demec JC (eds): Neoplasms of the Skin and Malignant Melanoma . Chicago, Year Book Medical Publishers Inc, 1976, p 19. 5. Paniago-Pereira C, Maize JC, Ackerman AB: Nevus of large spindle and/or epithelioid cells (Spitz's nevus) . Arch Dermatol 114:1811-1823, 1978.Crossref 6. Lever WF, Schaumburg-Lever G: Histopathology of the Skin . Philadelphia, JB Lippincott Co, 1975, p 671. 7. Okun M, Edelstein L: Gross and Microscopic Pathology of the Skin . Boston, Dermatopathology Foundation Press, 1976, vol 2, pp 958, 985. 8. McGovern V: Malignant Melanoma: Clinical and Histologic Diagnosis . New York, John Wiley & Sons Inc, 1976, p 149.

Journal

Archives of DermatologyAmerican Medical Association

Published: Dec 1, 1979

References

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