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Melanoma In Situ of the Sole That Extended Into a Skin Graft: Reflections on the Biology of Melanoma

Melanoma In Situ of the Sole That Extended Into a Skin Graft: Reflections on the Biology of Melanoma Abstract We report the unusual case of a 77-year-old black man who developed a recurrent melanoma on his right heel, encompassing the indigenous acral skin and the skin that had been taken from the donor site in the groin and grafted to the acral surface. Microscopic examination of the recurrent in situ melanoma growing in the two types of skin has provided a fresh perspective on the ''controversy'' regarding the pathophysiology of melanoma. Report of a Case. A 77-year-old black man presented at Columbia-Presbyterian Medical Center, New York, NY, with a pigmented lesion on the right heel.Ten years before, the patient had presented to another institution with a pigmented lesion at the same site that was present for an unknown length of time. An excisional biopsy specimen revealed in situ melanoma. The microscopic margins of resection were free of tumor; however, the gross description suggested that the area of pigmentation References 1. Clark WH Jr, Goldman LI, Mastrangelo MJ, eds. Human Malignant Melanoma . New York, NY: Grune & Stratton; 1979:33-123. 2. Elder DE, Jucovy PM, Tuthill RJ, Clark WH Jr. The classification of malignant melanoma . Am J Dermatopathol. 1980;2:315-319.Crossref 3. Elder DE, Jucovy PM, Clark WH Jr. Melanoma classification . Am J Dermatopathol. 1982;4:435-445.Crossref 4. Ackerman AB. Malignant melanoma: a unifying concept . Am J Dermatopathol. 1980;2:309-313.Crossref 5. Lieblich LM. Classification of malignant melanomas: a view of the current controversy . Am J Dermatopathol. 1982;4:435-441.Crossref 6. Ackerman AB. Disagreements about classification of malignant melanomas . Am J Dermatopathol. 1982;4:447-452.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Melanoma In Situ of the Sole That Extended Into a Skin Graft: Reflections on the Biology of Melanoma

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Publisher
American Medical Association
Copyright
Copyright © 1995 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1995.01690240134034
Publisher site
See Article on Publisher Site

Abstract

Abstract We report the unusual case of a 77-year-old black man who developed a recurrent melanoma on his right heel, encompassing the indigenous acral skin and the skin that had been taken from the donor site in the groin and grafted to the acral surface. Microscopic examination of the recurrent in situ melanoma growing in the two types of skin has provided a fresh perspective on the ''controversy'' regarding the pathophysiology of melanoma. Report of a Case. A 77-year-old black man presented at Columbia-Presbyterian Medical Center, New York, NY, with a pigmented lesion on the right heel.Ten years before, the patient had presented to another institution with a pigmented lesion at the same site that was present for an unknown length of time. An excisional biopsy specimen revealed in situ melanoma. The microscopic margins of resection were free of tumor; however, the gross description suggested that the area of pigmentation References 1. Clark WH Jr, Goldman LI, Mastrangelo MJ, eds. Human Malignant Melanoma . New York, NY: Grune & Stratton; 1979:33-123. 2. Elder DE, Jucovy PM, Tuthill RJ, Clark WH Jr. The classification of malignant melanoma . Am J Dermatopathol. 1980;2:315-319.Crossref 3. Elder DE, Jucovy PM, Clark WH Jr. Melanoma classification . Am J Dermatopathol. 1982;4:435-445.Crossref 4. Ackerman AB. Malignant melanoma: a unifying concept . Am J Dermatopathol. 1980;2:309-313.Crossref 5. Lieblich LM. Classification of malignant melanomas: a view of the current controversy . Am J Dermatopathol. 1982;4:435-441.Crossref 6. Ackerman AB. Disagreements about classification of malignant melanomas . Am J Dermatopathol. 1982;4:447-452.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Dec 1, 1995

References