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Meesmann's Corneal Dystrophy: A Pathological Study

Meesmann's Corneal Dystrophy: A Pathological Study Abstract A rare form of familial dystrophy of the corneal epithelium was described clinically by Pameijer1 in 1935. In 1938 Meesmann2 studied this dystrophy pathologically and found an abundance of glycogen in the corneal epithelium. Although other authors have described this dystrophy,3-6 none has identified conclusively as glycogen the deposits which Meesmann reported. The purpose of this communication is to report a case with histochemical and finestructural studies and to suggest a possible pathogenesis of the disease. Report of Case The propositus was a 31-year-old white female, who was first seen in the clinic of the Massachusetts Eye and Ear Infirmary in September, 1961. She had been sent on referral for diagnosis of "black spots" of unknown duration in the cornea. Her only subjective complaint was occasional ocular irritation.Vision with correction for myopic astigmatism in each eye was 20/40-2 OD and 20/60 OS. The corneas were studded References 1. Pameijer, J. K.: Über eine fremdartige familiäre oberflächliche Hornhautveränderung , Klin Mbl Augenheilk 95:516-517, 1935. 2. Meesmann, A., and Wilke, F.: Klinische und anatomische Untersuchungen über eine bisher unbekannte, dominant vererbte Epitheldystrophie der Hornhaut , Klin Mbl Augenheilk 103:361-391, 1939. 3. Böck, J.: Demonstration , Klin Mbl Augenheilk 107:97, 1941. 4. Bürki, E.: Zur Kenntnis der erblichen Epitheldystrophie der Hornhaut , Ophthalmologica 111:134-139, 1946.Crossref 5. Snyder, W. B.: Hereditary Epithelial Corneal Dystrophy , Amer J Ophthal 55:56-61, 1963. 6. Stocker, W., and Holt, L. B.: Rare Form of Hereditary Epithelial Dystrophy , AMA Arch Ophthal 53:536-541, 1955.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Meesmann's Corneal Dystrophy: A Pathological Study

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Publisher
American Medical Association
Copyright
Copyright © 1964 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1964.00970010692015
Publisher site
See Article on Publisher Site

Abstract

Abstract A rare form of familial dystrophy of the corneal epithelium was described clinically by Pameijer1 in 1935. In 1938 Meesmann2 studied this dystrophy pathologically and found an abundance of glycogen in the corneal epithelium. Although other authors have described this dystrophy,3-6 none has identified conclusively as glycogen the deposits which Meesmann reported. The purpose of this communication is to report a case with histochemical and finestructural studies and to suggest a possible pathogenesis of the disease. Report of Case The propositus was a 31-year-old white female, who was first seen in the clinic of the Massachusetts Eye and Ear Infirmary in September, 1961. She had been sent on referral for diagnosis of "black spots" of unknown duration in the cornea. Her only subjective complaint was occasional ocular irritation.Vision with correction for myopic astigmatism in each eye was 20/40-2 OD and 20/60 OS. The corneas were studded References 1. Pameijer, J. K.: Über eine fremdartige familiäre oberflächliche Hornhautveränderung , Klin Mbl Augenheilk 95:516-517, 1935. 2. Meesmann, A., and Wilke, F.: Klinische und anatomische Untersuchungen über eine bisher unbekannte, dominant vererbte Epitheldystrophie der Hornhaut , Klin Mbl Augenheilk 103:361-391, 1939. 3. Böck, J.: Demonstration , Klin Mbl Augenheilk 107:97, 1941. 4. Bürki, E.: Zur Kenntnis der erblichen Epitheldystrophie der Hornhaut , Ophthalmologica 111:134-139, 1946.Crossref 5. Snyder, W. B.: Hereditary Epithelial Corneal Dystrophy , Amer J Ophthal 55:56-61, 1963. 6. Stocker, W., and Holt, L. B.: Rare Form of Hereditary Epithelial Dystrophy , AMA Arch Ophthal 53:536-541, 1955.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: May 1, 1964

References

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