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Mediterranean Diet and White Matter Hyperintensity Volume in the Northern Manhattan Study

Mediterranean Diet and White Matter Hyperintensity Volume in the Northern Manhattan Study ORIGINAL CONTRIBUTION Mediterranean Diet and White Matter Hyperintensity Volume in the Northern Manhattan Study Hannah Gardener, ScD; Nikolaos Scarmeas, MD, MS; Yian Gu, PhD; Bernadette Boden-Albala, MPH, DrPh; Mitchell S. V. Elkind, MD, MS; Ralph L. Sacco, MD, MS; Charles DeCarli, MD; Clinton B. Wright, MD, MS Objective: To examine the association between a Medi- ciation between the MeDi score and the log-transformed terranean-style diet (MeDi) and brain magnetic resonance WMHV as a proportion of total cranial volume, control- imaging white matter hyperintensity volume (WMHV). ling for sociodemographic and vascular risk factors. Design: A cross-sectional analysis within a longitudi- Results: On the MeDi scale, 11.6% scored 0 to 2, 15.8% nal population-based cohort study. A semiquantitative scored 3, 23.0% scored 4, 23.5% scored 5, and 26.1% food frequency questionnaire was administered, and a scored 6 to 9. Each 1-point increase in MeDi score was score (range, 0-9) was calculated to reflect increasing simi- associated with a lower log WMHV ( = −.04, P = .01). The larity to the MeDi pattern. only MeDi score component that was an independent pre- dictor of WMHV was the ratio of monounsaturated to Setting: The Northern Manhattan Study. saturated fat ( = −.20, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

Mediterranean Diet and White Matter Hyperintensity Volume in the Northern Manhattan Study

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References (38)

Publisher
American Medical Association
Copyright
Copyright 2012 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/archneurol.2011.548
pmid
22332193
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL CONTRIBUTION Mediterranean Diet and White Matter Hyperintensity Volume in the Northern Manhattan Study Hannah Gardener, ScD; Nikolaos Scarmeas, MD, MS; Yian Gu, PhD; Bernadette Boden-Albala, MPH, DrPh; Mitchell S. V. Elkind, MD, MS; Ralph L. Sacco, MD, MS; Charles DeCarli, MD; Clinton B. Wright, MD, MS Objective: To examine the association between a Medi- ciation between the MeDi score and the log-transformed terranean-style diet (MeDi) and brain magnetic resonance WMHV as a proportion of total cranial volume, control- imaging white matter hyperintensity volume (WMHV). ling for sociodemographic and vascular risk factors. Design: A cross-sectional analysis within a longitudi- Results: On the MeDi scale, 11.6% scored 0 to 2, 15.8% nal population-based cohort study. A semiquantitative scored 3, 23.0% scored 4, 23.5% scored 5, and 26.1% food frequency questionnaire was administered, and a scored 6 to 9. Each 1-point increase in MeDi score was score (range, 0-9) was calculated to reflect increasing simi- associated with a lower log WMHV ( = −.04, P = .01). The larity to the MeDi pattern. only MeDi score component that was an independent pre- dictor of WMHV was the ratio of monounsaturated to Setting: The Northern Manhattan Study. saturated fat ( = −.20,

Journal

JAMA NeurologyAmerican Medical Association

Published: Feb 1, 2012

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