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MEDICAL NEWS

MEDICAL NEWS Clinical Trials Support Amantadine Clinical studies with amantadine hydrochloride indicate it is effective against the Hong Kong A2 strain of influenza virus, three investigators told a recent conference on antiviral substances, sponsored by the New York Academy of Sciences. Amantadine is a synthetic organic amine that appears to delay viral penetration of cells and interferes with viral replication. It has been used for treatment of Asian flu, but the US Food and Drug Administration last spring ordered E. I. du Pont de Nemours and Co. not to refer to amantadine as a drug that could protect against the Hong Kong flu because controlled clinical trials using the newly arisen strain had not been completed (JAMAMedical News206:489 [Oct 14] and 206:1188 [Nov 4] 1968). Investigators who made the studies are Richard B. Hornick, MD, of the University of Maryland School of Medicine; Capt Robert O. Peckinpaugh, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

MEDICAL NEWS

JAMA , Volume 208 (13) – Jun 30, 1969
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Publisher
American Medical Association
Copyright
Copyright © 1969 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1969.03160130005003
Publisher site
See Article on Publisher Site

Abstract

Clinical Trials Support Amantadine Clinical studies with amantadine hydrochloride indicate it is effective against the Hong Kong A2 strain of influenza virus, three investigators told a recent conference on antiviral substances, sponsored by the New York Academy of Sciences. Amantadine is a synthetic organic amine that appears to delay viral penetration of cells and interferes with viral replication. It has been used for treatment of Asian flu, but the US Food and Drug Administration last spring ordered E. I. du Pont de Nemours and Co. not to refer to amantadine as a drug that could protect against the Hong Kong flu because controlled clinical trials using the newly arisen strain had not been completed (JAMAMedical News206:489 [Oct 14] and 206:1188 [Nov 4] 1968). Investigators who made the studies are Richard B. Hornick, MD, of the University of Maryland School of Medicine; Capt Robert O. Peckinpaugh,

Journal

JAMA – American Medical Association

Published: Jun 30, 1969

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