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MEDICAL ASPECTS OF PANCREATITIS

MEDICAL ASPECTS OF PANCREATITIS The diagnosis of acute pancreatitis usually depends on the finding of a high serum amylase level in a patient with acute severe epigastric pain, abdominal tenderness, vomiting, fever, tachycardia, and leukocytosis. Increasingly exact methods of diagnosis have led to increasingly conservative methods of treatment. Therapy includes continuous aspiration of gastric contents, parenteral administration of solutions to preserve the water-electrolyte balance and combat shock, and use of antibiotics. The treatment must be adapted to the case, and surgery may be necessary. Chronic pancreatitis is usually seen in older patients after repeated attacks of acute pancreatitis, or during the progress of tuberculosis, syphilis, or hemochromatosis. Laboratory studies of the blood, especially determinations of pancreatic enzyme levels and glucose tolerance, are important in diagnosis. Chronic pancreatitis leads to diabetes, steatorrhea, and calcification, with the possibility of sudden fatal complications. Treatment is designed to eliminate, if possible, the cause of recurrences and to compensate, by means of insulin, pancreatin, and diet, for the loss of the internal and external secretions of the pancreas. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

MEDICAL ASPECTS OF PANCREATITIS

JAMA , Volume 169 (14) – Apr 4, 1959

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References (7)

Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1959.03000310023004
Publisher site
See Article on Publisher Site

Abstract

The diagnosis of acute pancreatitis usually depends on the finding of a high serum amylase level in a patient with acute severe epigastric pain, abdominal tenderness, vomiting, fever, tachycardia, and leukocytosis. Increasingly exact methods of diagnosis have led to increasingly conservative methods of treatment. Therapy includes continuous aspiration of gastric contents, parenteral administration of solutions to preserve the water-electrolyte balance and combat shock, and use of antibiotics. The treatment must be adapted to the case, and surgery may be necessary. Chronic pancreatitis is usually seen in older patients after repeated attacks of acute pancreatitis, or during the progress of tuberculosis, syphilis, or hemochromatosis. Laboratory studies of the blood, especially determinations of pancreatic enzyme levels and glucose tolerance, are important in diagnosis. Chronic pancreatitis leads to diabetes, steatorrhea, and calcification, with the possibility of sudden fatal complications. Treatment is designed to eliminate, if possible, the cause of recurrences and to compensate, by means of insulin, pancreatin, and diet, for the loss of the internal and external secretions of the pancreas.

Journal

JAMAAmerican Medical Association

Published: Apr 4, 1959

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