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Mediastinal and Cervical Histoplasmosis Simulating Malignancy

Mediastinal and Cervical Histoplasmosis Simulating Malignancy Abstract • A 12-year-old boy had a purulent mass in the anterior cervical region in association with an anterior mediastinal mass caused by Histoplasma capsulatum. The cervical mass probably represented spread of the disease, perhaps along the same pathways followed in Hodgkin's disease and other conditions that are known to involve the anterior mediastinum and the anterior cervical nodes simultaneously. An infectious disease (histoplasmosis) can cause a constellation of symptoms suggestive of a lymphoma or other malignancy. (Am J Dis Child 133:47-49, 1979) References 1. Rusby NL: Dermoid cysts and teratoma of mediastinum: Review . J Thorac Surg 13:169-222, 1944. 2. Keefer CS: Acute and chronic mediastinitis: Study of 60 cases . Arch Intern Med 62:109-136, 1938.Crossref 3. Caplan H: Patterns of Anatomic Distribution in Hodgkin's Disease . Cambridge, Mass, Harvard University Press, 1972, pp 196-243. 4. Haller JA, Mazur DO, Morgan WW Jr: Diagnosis and management of mediastinal masses in children . J Thorac Cardiovasc Surg 58:385-393, 1969. 5. Levin S: The fungal skin test as a prognostic hindrance . J Infect Dis 122:343-344, 1970.Crossref 6. Hughes WT: Histoplasmosis capsulation and atypical Mycobacterium . Am J Dis Child 110:89, 1965.Crossref 7. Goodwin RA, Nickell JA, Des Prez RM: Mediastinal fibrosis complicating healed primary histoplasmosis and tuberculosis . Medicine 51:227-246, 1972.Crossref 8. Scully RE, Galdabini JJ, McNeely BU: Case records of the Massachusetts General Hospital: Weekly clinicopathological exercises . N Engl J Med 295:381-388, 1976.Crossref 9. Zajtchuk R, Strevey TE, Heydorn WH, et al: Mediastinal histoplasmosis: Surgical considerations . J Thorac Cardiovasc Surg 66:300-304, 1973. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Mediastinal and Cervical Histoplasmosis Simulating Malignancy

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References (13)

Publisher
American Medical Association
Copyright
Copyright © 1979 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1979.02130010053009
Publisher site
See Article on Publisher Site

Abstract

Abstract • A 12-year-old boy had a purulent mass in the anterior cervical region in association with an anterior mediastinal mass caused by Histoplasma capsulatum. The cervical mass probably represented spread of the disease, perhaps along the same pathways followed in Hodgkin's disease and other conditions that are known to involve the anterior mediastinum and the anterior cervical nodes simultaneously. An infectious disease (histoplasmosis) can cause a constellation of symptoms suggestive of a lymphoma or other malignancy. (Am J Dis Child 133:47-49, 1979) References 1. Rusby NL: Dermoid cysts and teratoma of mediastinum: Review . J Thorac Surg 13:169-222, 1944. 2. Keefer CS: Acute and chronic mediastinitis: Study of 60 cases . Arch Intern Med 62:109-136, 1938.Crossref 3. Caplan H: Patterns of Anatomic Distribution in Hodgkin's Disease . Cambridge, Mass, Harvard University Press, 1972, pp 196-243. 4. Haller JA, Mazur DO, Morgan WW Jr: Diagnosis and management of mediastinal masses in children . J Thorac Cardiovasc Surg 58:385-393, 1969. 5. Levin S: The fungal skin test as a prognostic hindrance . J Infect Dis 122:343-344, 1970.Crossref 6. Hughes WT: Histoplasmosis capsulation and atypical Mycobacterium . Am J Dis Child 110:89, 1965.Crossref 7. Goodwin RA, Nickell JA, Des Prez RM: Mediastinal fibrosis complicating healed primary histoplasmosis and tuberculosis . Medicine 51:227-246, 1972.Crossref 8. Scully RE, Galdabini JJ, McNeely BU: Case records of the Massachusetts General Hospital: Weekly clinicopathological exercises . N Engl J Med 295:381-388, 1976.Crossref 9. Zajtchuk R, Strevey TE, Heydorn WH, et al: Mediastinal histoplasmosis: Surgical considerations . J Thorac Cardiovasc Surg 66:300-304, 1973.

Journal

American Journal of Diseases of Children – American Medical Association

Published: Jan 1, 1979

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