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MANAGEMENT OF RHEUMATOID ARTHRITIS

MANAGEMENT OF RHEUMATOID ARTHRITIS Abstract MOST CURRENT reports on rheumatic diseases deal with treatment; many compare the effects of particular pharmaceutical agents. Properly regarded as fragments of clinical investigation, such reports do not mean that the successful management of rheumatoid arthritis depends on the administration of one or the other medicine. To be sure, several drugs have definite, more or less circumscribed usefulness. Some rheumatoid patients treated with a new preparation may also have been substantially improved at some time. But if one in practice were to rely foremost on his selection of antirheumatic drugs, he would oftener than not make merely a choice of embarrassments. Rationale There is as yet no remedy which can be counted upon to arrest rheumatoid arthritis. None has induced remissions as consistently as have either pregnancy or jaundice. But even though Factor X, credited by Hench with reversibility of rheumatoid arthritis, remains unknown, the disease also commonly abates under References 1. Baker, F.: The Rationale for Physical Therapy in Arthritis , Bull. Rheumat. Dis. 4:40, 1953. 2. Bunim, J. J.; Pechet, M. M., and Bollet, A. J.: Studies on Metacortandralone and Metacortandracin in Rheumatoid Arthritis: Antirheumatic Potency, Metabolic Effects, and Hormonal Properties , J.A.M.A. 157:311, 1955.Crossref 3. Duthie, J. J. R.: The Value of Long-Term Conservative Treatment in Rheumatoid Arthritis , Bull. Rheumat. Dis. 4:54, 1954. 4. Empire Rheumatism Council: Multi-Centre Controlled Trial Comparing Cortisone Acetate and Acetyl Salicylic Acid in the Long-Term Treatment of Rheumatoid Arthritis: Results up to One Year Ann. Rheumat. Dis. 14:353, 1955.Crossref 5. Fredell, E. W.; Johnson, H. P.; Krupp, M. A.; Engleman, E. P., and McGrath, A. K.: Adrenocortical Function During Long-Term Cortisone Therapy: Further Observations , A.M.A. Arch. Int. Med. 95:411, 1955.Crossref 6. Freyberg, R. H.: Present Status of Gold Therapy for Rheumatoid Arthritis , J.A.M.A. 143:418, 1950.Crossref 7. Hench, P. S.: Potential Reversibility of Rheumatoid Arthritis , Ann. Rheumat. Dis. 8:90, 1949.Crossref 8. Hollander, J. L.; Abrams, N. R., and others: Comroe's Arthritis and Allied Conditions. Ed. 5, Philadelphia, Lea & Febiger, 1953. Jellinek, K., to be published. 9. Lowman, E. W.; Lee, P. R., and Rusk, H. A.: Total Rehabilitation of the Rheumatoid Arthritic Cripple , J.A.M.A. 158:1335, 1955.Crossref 10. Meyer, K., and Ragan, C.: The Antirheumatic Effect of Sodium Gentisate , Science 108:281, 1948.Crossref 11. Ragan, C.: The Present-Day Management of Arthritis , J. Chron. Dis. 1:253, 1955.Crossref 12. Reynolds, W. E.; Bauer, W., and Beauregard, J. M.: Rheumatoid Arthritis with Remissions: A Study of 80 Patients , Ann. Rheumat. Dis. 13:362, 1954. 13. Short, C. L., and Bauer, W.: Course of Rheumatoid Arthritis in Patients Receiving Simple Medical and Orthopedic Measures , New England J. Med. 238:142, 1948.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Internal Medicine American Medical Association

MANAGEMENT OF RHEUMATOID ARTHRITIS

A.M.A. Archives of Internal Medicine , Volume 98 (3) – Sep 1, 1956

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Publisher
American Medical Association
Copyright
Copyright © 1956 American Medical Association. All Rights Reserved.
ISSN
0888-2479
DOI
10.1001/archinte.1956.00250270076009
Publisher site
See Article on Publisher Site

Abstract

Abstract MOST CURRENT reports on rheumatic diseases deal with treatment; many compare the effects of particular pharmaceutical agents. Properly regarded as fragments of clinical investigation, such reports do not mean that the successful management of rheumatoid arthritis depends on the administration of one or the other medicine. To be sure, several drugs have definite, more or less circumscribed usefulness. Some rheumatoid patients treated with a new preparation may also have been substantially improved at some time. But if one in practice were to rely foremost on his selection of antirheumatic drugs, he would oftener than not make merely a choice of embarrassments. Rationale There is as yet no remedy which can be counted upon to arrest rheumatoid arthritis. None has induced remissions as consistently as have either pregnancy or jaundice. But even though Factor X, credited by Hench with reversibility of rheumatoid arthritis, remains unknown, the disease also commonly abates under References 1. Baker, F.: The Rationale for Physical Therapy in Arthritis , Bull. Rheumat. Dis. 4:40, 1953. 2. Bunim, J. J.; Pechet, M. M., and Bollet, A. J.: Studies on Metacortandralone and Metacortandracin in Rheumatoid Arthritis: Antirheumatic Potency, Metabolic Effects, and Hormonal Properties , J.A.M.A. 157:311, 1955.Crossref 3. Duthie, J. J. R.: The Value of Long-Term Conservative Treatment in Rheumatoid Arthritis , Bull. Rheumat. Dis. 4:54, 1954. 4. Empire Rheumatism Council: Multi-Centre Controlled Trial Comparing Cortisone Acetate and Acetyl Salicylic Acid in the Long-Term Treatment of Rheumatoid Arthritis: Results up to One Year Ann. Rheumat. Dis. 14:353, 1955.Crossref 5. Fredell, E. W.; Johnson, H. P.; Krupp, M. A.; Engleman, E. P., and McGrath, A. K.: Adrenocortical Function During Long-Term Cortisone Therapy: Further Observations , A.M.A. Arch. Int. Med. 95:411, 1955.Crossref 6. Freyberg, R. H.: Present Status of Gold Therapy for Rheumatoid Arthritis , J.A.M.A. 143:418, 1950.Crossref 7. Hench, P. S.: Potential Reversibility of Rheumatoid Arthritis , Ann. Rheumat. Dis. 8:90, 1949.Crossref 8. Hollander, J. L.; Abrams, N. R., and others: Comroe's Arthritis and Allied Conditions. Ed. 5, Philadelphia, Lea & Febiger, 1953. Jellinek, K., to be published. 9. Lowman, E. W.; Lee, P. R., and Rusk, H. A.: Total Rehabilitation of the Rheumatoid Arthritic Cripple , J.A.M.A. 158:1335, 1955.Crossref 10. Meyer, K., and Ragan, C.: The Antirheumatic Effect of Sodium Gentisate , Science 108:281, 1948.Crossref 11. Ragan, C.: The Present-Day Management of Arthritis , J. Chron. Dis. 1:253, 1955.Crossref 12. Reynolds, W. E.; Bauer, W., and Beauregard, J. M.: Rheumatoid Arthritis with Remissions: A Study of 80 Patients , Ann. Rheumat. Dis. 13:362, 1954. 13. Short, C. L., and Bauer, W.: Course of Rheumatoid Arthritis in Patients Receiving Simple Medical and Orthopedic Measures , New England J. Med. 238:142, 1948.Crossref

Journal

A.M.A. Archives of Internal MedicineAmerican Medical Association

Published: Sep 1, 1956

References