Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Magnetic Resonance Imaging Screening to Identify Spinal and Paraspinal Infections Associated With Injections of Contaminated Methylprednisolone Acetate

Magnetic Resonance Imaging Screening to Identify Spinal and Paraspinal Infections Associated With... ORIGINAL CONTRIBUTION Magnetic Resonance Imaging Screening to Identify Spinal and Paraspinal Infections Associated With Injections of Contaminated Methylprednisolone Acetate Anurag N. Malani, MD Importance Injection of contaminated methylprednisolone has resulted in an unprec- David M. Vandenberg, MD edented nationwide outbreak of Exserohilum rostratum fungal infections, manifested ini- tially as meningitis and/or basilar stroke. Insidious onset of spinal or paraspinal infection Bonita Singal, MD, PhD at the injection site has been increasingly reported and is occurring months after receipt Michael Kasotakis, MD of injection with the contaminated drug. The clinical findings are often subtle and similar to those that led the patient to undergo the methylprednisolone injection. Spencer Koch, MD Objective To determine if patients who had not presented for medical care but who had Varsha Moudgal, MD received contaminated methylprednisolone developed spinal or paraspinal infection at the Rajasekhar Jagarlamudi, MD injection site using contrast-enhanced magnetic resonance imaging (MRI) screening. Anupama Neelakanta, MD Design, Setting, and Participants There were 172 patients who had received Michael H. Otto, MD an injection of contaminated methylprednisolone from a highly contaminated lot (No. 06292012@26) at a pain facility but had not presented for medical care related Lakshmi Halasyamani, MD to adverse effects after the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Magnetic Resonance Imaging Screening to Identify Spinal and Paraspinal Infections Associated With Injections of Contaminated Methylprednisolone Acetate

Loading next page...
 
/lp/american-medical-association/magnetic-resonance-imaging-screening-to-identify-spinal-and-paraspinal-QY1RP0KLPo
Publisher
American Medical Association
Copyright
Copyright 2013 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2013.6293
pmid
23780459
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL CONTRIBUTION Magnetic Resonance Imaging Screening to Identify Spinal and Paraspinal Infections Associated With Injections of Contaminated Methylprednisolone Acetate Anurag N. Malani, MD Importance Injection of contaminated methylprednisolone has resulted in an unprec- David M. Vandenberg, MD edented nationwide outbreak of Exserohilum rostratum fungal infections, manifested ini- tially as meningitis and/or basilar stroke. Insidious onset of spinal or paraspinal infection Bonita Singal, MD, PhD at the injection site has been increasingly reported and is occurring months after receipt Michael Kasotakis, MD of injection with the contaminated drug. The clinical findings are often subtle and similar to those that led the patient to undergo the methylprednisolone injection. Spencer Koch, MD Objective To determine if patients who had not presented for medical care but who had Varsha Moudgal, MD received contaminated methylprednisolone developed spinal or paraspinal infection at the Rajasekhar Jagarlamudi, MD injection site using contrast-enhanced magnetic resonance imaging (MRI) screening. Anupama Neelakanta, MD Design, Setting, and Participants There were 172 patients who had received Michael H. Otto, MD an injection of contaminated methylprednisolone from a highly contaminated lot (No. 06292012@26) at a pain facility but had not presented for medical care related Lakshmi Halasyamani, MD to adverse effects after the

Journal

JAMAAmerican Medical Association

Published: Jun 19, 2013

References