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Lymphomatoid Granulomatosis of the Skin: A New Clinicopathologic Entity

Lymphomatoid Granulomatosis of the Skin: A New Clinicopathologic Entity Abstract Lymphomatoid granulomatosis is a necrotizing arteritis primarily affecting the lungs but also found in the skin, kidneys, central nervous system, and other extrapulmonary sites. Cutaneous involvement occurred in 45% of the cases described by Liebow in his original series. Light microscopy studies were performed. The IgA and IgG levels were slightly decreased and the IgE level was elevated. Cell-mediated immunity was impaired. No viruses were isolated or identified by immunofluorescence. A man had cutaneous lesions as the first sign of lymphomatoid granulomatosis. References 1. Liebow AA, Carrington CRB, Friedman PJ: Lymphomatoid granulomatosis . Hum Pathol 3:457-558, 1972.Crossref 2. Kay S, Fu YS, Minars N, et al: Lymphomatoid granulomatosis of the skin: Light microscopic and ultrastructural studies . Cancer , to be published. 3. Pagano JS, Huang CH, Levine P: Absence of Epstein-Barr viral DNA in American Burkitt's lymphoma . N Engl J Med 289:1395-1399, 1973.Crossref 4. Epstein MA, Achong BG: Various forms of Epstein-Barr virus infections in man: Established facts and a general concept . Lancet 2:836-839, 1973.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Lymphomatoid Granulomatosis of the Skin: A New Clinicopathologic Entity

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Publisher
American Medical Association
Copyright
Copyright © 1975 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1975.01630160083009
Publisher site
See Article on Publisher Site

Abstract

Abstract Lymphomatoid granulomatosis is a necrotizing arteritis primarily affecting the lungs but also found in the skin, kidneys, central nervous system, and other extrapulmonary sites. Cutaneous involvement occurred in 45% of the cases described by Liebow in his original series. Light microscopy studies were performed. The IgA and IgG levels were slightly decreased and the IgE level was elevated. Cell-mediated immunity was impaired. No viruses were isolated or identified by immunofluorescence. A man had cutaneous lesions as the first sign of lymphomatoid granulomatosis. References 1. Liebow AA, Carrington CRB, Friedman PJ: Lymphomatoid granulomatosis . Hum Pathol 3:457-558, 1972.Crossref 2. Kay S, Fu YS, Minars N, et al: Lymphomatoid granulomatosis of the skin: Light microscopic and ultrastructural studies . Cancer , to be published. 3. Pagano JS, Huang CH, Levine P: Absence of Epstein-Barr viral DNA in American Burkitt's lymphoma . N Engl J Med 289:1395-1399, 1973.Crossref 4. Epstein MA, Achong BG: Various forms of Epstein-Barr virus infections in man: Established facts and a general concept . Lancet 2:836-839, 1973.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Apr 1, 1975

References

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