Abstract IN TWO recent papers the entity of lymphocytoma of the skin was discussed for the first time in the American dermatologic literature.1 The disease has been recognized for many years, however, both as lymphocytoma and as Spiegler-Fendt sarcoid, as reported by Lewis2 and others. In 1943 the subject was comprehensively reviewed in a monograph by Bäfverstedt.3 This author, like Lewis, distinguished two clinical types: the isolated or regionally localized type, and the multiple disseminated type. Clinically, lymphocytoma presents a variable picture, with lesions usually on the face, characterized by small size, slow growth, absence or paucity of subjective symptoms, and no intrusion of cancerous change. Histologically, the lesions consist of a highly differentiated lymphoid tissue, with or without germinal centers. Pursuing a benign course, they may persist indefinitely or they may disappear spontaneously. As a rule they exhibit marked sensitivity to roentgen irradiation. The following case is References 1. Loveman, A. B., and Fliegelman, M. T.: Lymphocytoma Cutis: Report of Two Cases , A. M. A. Arch. Dermat. & Syph. 63:169-181 ( (Feb.) ) 1951. 2. Mopper, C., and Rogin, J. R.: Benign Solitary Lymphocytoma: Report of Three Cases , A. M. A. Arch. Dermat. & Syph. 63:184-190 ( (Feb.) ) 1951. 3. Lewis, G. M.: Is Spiegler-Fendt Sarcoid a Clinical or Histologic Entity? Arch. Dermat. & Syph. 31:67-81, 1935. 4. Bäfverstedt, B.: Über Lymphadenosis benigna cutis: eine klinische und pathologischanatomische Studie , Acta dermat.-venereol. ( (supp. 11) ) 24:1-202, 1943. 5. Epstein, S.: Lymphocytome der Haut mit Beteiligung der Conjunctiva bulbi , Arch. Dermat. u. Syph. 173:181-195, 1935. 6. Dr. Hamilton Montgomery examined the slides and gave helpful advice. 7. Maximow, A. A., and Bloom, W.: A Textbook of Histology , Philadelphia, W. B. Saunders Company, 1948, pp. 260-269. 8. Bianchi, G. E.: Die Penicillinbehandlung der Lymphozytome , Dermatologica 100:270-273, 1950. 9. Miescher, cited by Gräflin, G.: Granulomatosen noch ungeklärter Natur , Dermatologica 100:397-407, 1950. 10. Ormsby, O. S., and Montgomery, H.: Diseases of the Skin , Philadelphia, Lea & Febiger, 1948, p. 873.
A.M.A. Archives of Dermatology & Syphilology – American Medical Association
Published: Dec 1, 1951