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Longitudinal Structure-Function Relationships With Scanning Laser Ophthalmoscopy and Standard Achromatic Perimetry

Longitudinal Structure-Function Relationships With Scanning Laser Ophthalmoscopy and Standard... CLINICAL SCIENCES Longitudinal Structure-Function Relationships With Scanning Laser Ophthalmoscopy and Standard Achromatic Perimetry Nariman Nassiri, MD; Naveed Nilforushan, MD; Anne L. Coleman, MD, PhD; Simon K. Law, MD, PharmD; Joseph Caprioli, MD; Kouros Nouri-Mahdavi, MD, MSc Objective: To explore longitudinal correlations be- mm /y). Glaucoma progressed in 38 (35.2%) and 20 tween structural and functional rates of glaucoma pro- (18.5%) eyes based on event and trend mean deviation gression with confocal scanning laser ophthalmoscopy criteria, respectively. The highest correlations of rates were and standard achromatic perimetry. observed between the superonasal or superotemporal RA and inferior VF clusters ( = 0.25-0.39; P .03). Fol- Methods: In this retrospective longitudinal study, 108 low-up time, baseline RA, and their interaction were the eyes with suspected or established glaucoma and 5 or more only significant predictors for RA change; belonging to good-quality scanning laser ophthalmoscopy examina- the group with progression was not associated with higher tions (global pixel SD 50 µm) and 6 or more reliable rates of RA progression. visual field (VF) examinations were included. Global and regional rates of progression for VF sensitivity and rim Conclusions: Longitudinal structure-function relation- area (RA) were calculated with linear regression analy- ships are fair at http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Ophthalmology American Medical Association

Longitudinal Structure-Function Relationships With Scanning Laser Ophthalmoscopy and Standard Achromatic Perimetry

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References (33)

Publisher
American Medical Association
Copyright
Copyright 2012 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6165
eISSN
2168-6173
DOI
10.1001/archophthalmol.2012.1057
pmid
22776919
Publisher site
See Article on Publisher Site

Abstract

CLINICAL SCIENCES Longitudinal Structure-Function Relationships With Scanning Laser Ophthalmoscopy and Standard Achromatic Perimetry Nariman Nassiri, MD; Naveed Nilforushan, MD; Anne L. Coleman, MD, PhD; Simon K. Law, MD, PharmD; Joseph Caprioli, MD; Kouros Nouri-Mahdavi, MD, MSc Objective: To explore longitudinal correlations be- mm /y). Glaucoma progressed in 38 (35.2%) and 20 tween structural and functional rates of glaucoma pro- (18.5%) eyes based on event and trend mean deviation gression with confocal scanning laser ophthalmoscopy criteria, respectively. The highest correlations of rates were and standard achromatic perimetry. observed between the superonasal or superotemporal RA and inferior VF clusters ( = 0.25-0.39; P .03). Fol- Methods: In this retrospective longitudinal study, 108 low-up time, baseline RA, and their interaction were the eyes with suspected or established glaucoma and 5 or more only significant predictors for RA change; belonging to good-quality scanning laser ophthalmoscopy examina- the group with progression was not associated with higher tions (global pixel SD 50 µm) and 6 or more reliable rates of RA progression. visual field (VF) examinations were included. Global and regional rates of progression for VF sensitivity and rim Conclusions: Longitudinal structure-function relation- area (RA) were calculated with linear regression analy- ships are fair at

Journal

JAMA Ophthalmology – American Medical Association

Published: Jul 1, 2012

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