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Long-Term Triamcinolone Acetonide Therapy-Reply

Long-Term Triamcinolone Acetonide Therapy-Reply This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.— We, too, have treated many patients with periodic injections of triamcinolone acetonide for control of various dermatologic conditions and plan to continue to do so. We saw very few important side effects and initiated the published study to determine whether or not relatively higher doses of triamcinolone acetonide could be safely administered for more severe conditions (eg, lupus erythematosus, rheumatoid arthritis, exfoliative erythroderma).Prospectively, we obtained metyrapone tartrate tests every two weeks following discontinuation of treatment with triamcinolone acetonide to determine how long it takes the hypothalamic-pituitary-adrenal axis to recover from the steroid suppression. Spot checks of the stored blood samples showed us that we anticipated much too early a recovery, and the reported results represent only a few of the metyrapone tests obtained. Also, the finding of steroid cataracts in two of the five subjects studied, in our opinion, is most meaningful.Our study and findings were http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Long-Term Triamcinolone Acetonide Therapy-Reply

Archives of Dermatology , Volume 112 (9) – Sep 1, 1976

Long-Term Triamcinolone Acetonide Therapy-Reply

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.— We, too, have treated many patients with periodic injections of triamcinolone acetonide for control of various dermatologic conditions and plan to continue to do so. We saw very few important side effects and initiated the published study to determine whether or not relatively higher doses of triamcinolone acetonide could be safely...
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Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1976.01630330081037
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.— We, too, have treated many patients with periodic injections of triamcinolone acetonide for control of various dermatologic conditions and plan to continue to do so. We saw very few important side effects and initiated the published study to determine whether or not relatively higher doses of triamcinolone acetonide could be safely administered for more severe conditions (eg, lupus erythematosus, rheumatoid arthritis, exfoliative erythroderma).Prospectively, we obtained metyrapone tartrate tests every two weeks following discontinuation of treatment with triamcinolone acetonide to determine how long it takes the hypothalamic-pituitary-adrenal axis to recover from the steroid suppression. Spot checks of the stored blood samples showed us that we anticipated much too early a recovery, and the reported results represent only a few of the metyrapone tests obtained. Also, the finding of steroid cataracts in two of the five subjects studied, in our opinion, is most meaningful.Our study and findings were

Journal

Archives of DermatologyAmerican Medical Association

Published: Sep 1, 1976

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