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LONG-TERM TREATMENT WITH IDOXURIDINE AND STEROIDS

LONG-TERM TREATMENT WITH IDOXURIDINE AND STEROIDS This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor: A note of caution should be added to the article by Drs. Dohlman and Zucker on "Long-term Treatment with Idoxuridine and Steroids," (Arch Ophthal 74:172-174, 1965). Concomitant administration of topical antibiotics with idoxuridine and steroids may prevent secondary bacterial infections, but an additional risk is undertaken—that of secondary mycotic keratitis.I recently saw a 25-year-old landscaper with a left herpetic keratitis (with slight stromal involvement) and iritis. Treatment consisted of idoxuridine ointment and suspension of prednisolone acetate 0.5% with polymyxin B sulfate and neomycin sulfate five times a day, and atropine. By the seventh day the stroma was clear and the dendrite was almost gone; treatment was continued. Three days later a white corneal ulcer appeared at the site of the former dendrite. Two days later, the infection appeared typically mycotic. Scraping and culture revealed Cephalosporium. Previous medication was replaced with hourly instillations of amphotericin B. When http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

LONG-TERM TREATMENT WITH IDOXURIDINE AND STEROIDS

Archives of Ophthalmology , Volume 74 (5) – Nov 1, 1965

LONG-TERM TREATMENT WITH IDOXURIDINE AND STEROIDS

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor: A note of caution should be added to the article by Drs. Dohlman and Zucker on "Long-term Treatment with Idoxuridine and Steroids," (Arch Ophthal 74:172-174, 1965). Concomitant administration of topical antibiotics with idoxuridine and steroids may prevent secondary bacterial infections, but an additional risk is...
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Publisher
American Medical Association
Copyright
Copyright © 1965 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1965.00970040703025
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor: A note of caution should be added to the article by Drs. Dohlman and Zucker on "Long-term Treatment with Idoxuridine and Steroids," (Arch Ophthal 74:172-174, 1965). Concomitant administration of topical antibiotics with idoxuridine and steroids may prevent secondary bacterial infections, but an additional risk is undertaken—that of secondary mycotic keratitis.I recently saw a 25-year-old landscaper with a left herpetic keratitis (with slight stromal involvement) and iritis. Treatment consisted of idoxuridine ointment and suspension of prednisolone acetate 0.5% with polymyxin B sulfate and neomycin sulfate five times a day, and atropine. By the seventh day the stroma was clear and the dendrite was almost gone; treatment was continued. Three days later a white corneal ulcer appeared at the site of the former dendrite. Two days later, the infection appeared typically mycotic. Scraping and culture revealed Cephalosporium. Previous medication was replaced with hourly instillations of amphotericin B. When

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Nov 1, 1965

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