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- Publisher
- American Medical Association
- Copyright
- Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
- ISSN
- 2168-6106
- eISSN
- 2168-6114
- DOI
- 10.1001/archinternmed.2010.311
- pmid
- 20876406
- Publisher site
- See Article on Publisher Site
Abstract
ORIGINAL INVESTIGATION Follow-up of a Randomized Trial in Older Women With Osteopenia Raija Korpelainen, PhD; Sirkka Keinänen-Kiukaanniemi, MD, PhD; Pentti Nieminen, PhD; Jorma Heikkinen, MD, PhD; Kalervo Väänänen, MD, PhD; Juha Korpelainen, MD, PhD Background: Long-term evidence from randomized The bone mineral density decreased similarly across time trials of the effectiveness of exercise in preventing dis- in both groups. The incidence rate of fractures during ability and fall-related fractures in elderly people has the total follow-up among women in the exercise group been lacking. vs women in the control group was 0.05 vs 0.08 per 1000 person-years (Poisson incidence rate ratio, 0.68; 95% con- Methods: We performed extended follow-up of 160 fidence interval, 0.34-1.32). There were no hip frac- women (aged 70-73 years at baseline) with osteopenia tures in the exercise group, whereas 5 hip fractures oc- in a population-based, randomized, controlled exercise curred in the control group. One woman in the exercise trial. The trial was conducted from April 1 through April group and 8 women in the control group died (Poisson 30, 2001. Follow-up was conducted from May 1, 2001, incidence rate ratio, 0.11; 95% confidence interval, 0.01- through December 31, 2005. Mean total time in obser-
Journal
JAMA Internal Medicine – American Medical Association
Published: Sep 27, 2010