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LOCAL USE OF VITAMIN A PREPARATIONS IN OPHTHALMIC PRACTICE

LOCAL USE OF VITAMIN A PREPARATIONS IN OPHTHALMIC PRACTICE Abstract The local application of vitamin A is of greater significance in the field of ophthalmology than is oral or intramuscular administration. In moderate climates this method of application of vitamin A does not extend to the general avitaminoses (keratomalacia and similar diseases). Such conditions are rare in Hungary. The aspecific action of this vitamin consists of epithelization and protection of the epithelium. It is not impossible that some conditions which respond to this form of therapy are due to local vitamin deficiency without being a general avitaminosis. It has always been a custom among laymen to apply milk and butter to the eye for the treatment of various ocular diseases irrespective of their etiology ; nevertheless, such treatment must now be considered as local vitamin therapy, although sometimes it is falsely indicated. The mysterious cure of Tobias' disease (serpent ulcer?), which was effected by the local application of fish liver, may References 1. Balachovski, S.: Sur la possibilité d'insuffisances locales en vitamines , Presse méd. 42:1404, 1934. 2. Kaptsiovskaya, R. S.: Clinical Characteristics of Carotene Used in Treatment of External Diseases of the Eye , Sovet. vestnik oftal. 5:242, 1934. 3. Rachevskij, F. A.: Provitamin A as Anti-Inflammatory Factor in Diseases of the Eye , Sovet. vestnik oftal. 4:470, 1934 4. abstracted, Physiologische und therapeutische Wirkung von Kolloidallösungen des Provitamins A bei dessen lokaler Anwendung am Auge , Klin. Wchnschr. 13:918, 1934. 5. Towbin, B. G.: Ein Versuch der Carotinverwendung bei Hornhautverpflanzung , Ztschr. f. Augenh. 88:107, 1936. 6. Villard, H.; Viallefont, H., and Diacono, E.: Greffe de la cornée chez le lapin et vitamine A , Arch. Soc. d. sc. méd. et biol. de Montpellier 16:423, 1935. 7. Pashkovskij, V. M.: Effect of Carotene in Certain External Diseases of the Eye , Sovet. vestnik oftal. 7:500, 1935. 8. Meshcherskij, N. N.: Carotene in the Therapy of Herpetic Keratitis , Vestnik oftal. 10:419, 1937. 9. Stevenson, E.: Cod Liver Oil as a Local Treatment for External Affections of the Eyes , Brit. J. Ophth. 20:416, 1936.Crossref 10. Federici, E.: Le vitamine A e D nei processi di riparazione della cornea (studio sperimentale) , Boll. d'ocul. 16:357, 1937. 11. Rinaldi, S.: Le vitamine A e D nel trattamento locale di lesioni corneali (ricerche sperimentali e cliniche) , Ann. di ottal. e clin. ocul. 64:505, 1936. 12. Clausen: Demonstrationen (case 23) , Klin. Monatsbl. f. Augenh. 96:524, 1936. 13. Romeick, in discussion on Clausen, p. 526. 14. Villard, H. ; Viallefont, H., and Diacono, E. : Kératite ulcéreuse trophique guérie par vitaminothérapie locale , Arch. Soc. d. sc. méd. et biol. de Montpellier 16:302, 1935. 15. Heinsius, E.: Experimentelle Untersuchungen über den Einfluss des Vitamin A auf die Regeneration des Hornhautepithels , Arch. f. Ophth. 136:103, 1937 16. Lokale Verwendung von Vitamin-A-haltigen Salben in der Augenheilkunde , Klin. Monatsbl. f. Augenh. 98:246, 1937. 17. Viallefont, H., and Diacono, E. : Le rôle des vitamines en ophthalmologie , Arch. d'opht. 52:723, 1935. 18. Vanýsek, J.: Bedeutung des Vitamins A bei der Regeneration von Hornhautgewebe , Českoslov. oftal. 3:189, 1937. 19. Kentgens, S. K.: Ueber Vitamin-A-Therapie bei Hornhauterkrankungen , Ophthalmologica 96:3, 1938.Crossref 20. This product is prepared by Messrs. Gedeon Richter, Ltd., Budapest. 21. (a) Horn, Z., and Sándor, I.: Local Application of Vitamin A in Therapy of Wounds , Orvosi hetil. 78:261, 1934. 22. (b) Sándor, I.: Vitamin A (Vulnovitan) in the Local Treatment of Wounds , Orvosi hetil. 80:505, 1936. 23. Ferenczy, Z., cited by Sándor.16b 24. von Grósz, S.: Short-Wave Therapy in Ophthalmology , Orvosképzés 27: 94, 1937. 25. von Grósz, S.: Bedeutung der B-Vitamine in der Augenheilkunde , Arch. f. Ophth. 140:149, 1939. 26. Mellanby, E.: Durch mangelhafte Ernährung bedingte Erkrankungen des Nervensystems , Schweiz. med. Wchnschr. 67:349, 1936. 27. Hanke, V.: Die degenerativen und neurotrophischen Hornhauterkrankungen , Zentralbl. f. d. ges. Ophth. 36:465, 1936. 28. von Grósz, S.: Aetiologie und Therapie der Keratoconjunctivitis sicca , Klin. Monatsbl. f. Augenh. 97:472, 1936. 29. Cerise, L., and Thurel, R.: L'anesthésie pathologique de la cornée , Tours. Arrault & Cie, 1931. 30. Martin, P.: Effects of Irradiation of the Eye by Radium , Tr. Ophth. Soc. U. Kingdom 53:246, 1933. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

LOCAL USE OF VITAMIN A PREPARATIONS IN OPHTHALMIC PRACTICE

Archives of Ophthalmology , Volume 22 (5) – Nov 1, 1939

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Publisher
American Medical Association
Copyright
Copyright © 1939 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1939.00860110013001
Publisher site
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Abstract

Abstract The local application of vitamin A is of greater significance in the field of ophthalmology than is oral or intramuscular administration. In moderate climates this method of application of vitamin A does not extend to the general avitaminoses (keratomalacia and similar diseases). Such conditions are rare in Hungary. The aspecific action of this vitamin consists of epithelization and protection of the epithelium. It is not impossible that some conditions which respond to this form of therapy are due to local vitamin deficiency without being a general avitaminosis. It has always been a custom among laymen to apply milk and butter to the eye for the treatment of various ocular diseases irrespective of their etiology ; nevertheless, such treatment must now be considered as local vitamin therapy, although sometimes it is falsely indicated. The mysterious cure of Tobias' disease (serpent ulcer?), which was effected by the local application of fish liver, may References 1. Balachovski, S.: Sur la possibilité d'insuffisances locales en vitamines , Presse méd. 42:1404, 1934. 2. Kaptsiovskaya, R. S.: Clinical Characteristics of Carotene Used in Treatment of External Diseases of the Eye , Sovet. vestnik oftal. 5:242, 1934. 3. Rachevskij, F. A.: Provitamin A as Anti-Inflammatory Factor in Diseases of the Eye , Sovet. vestnik oftal. 4:470, 1934 4. abstracted, Physiologische und therapeutische Wirkung von Kolloidallösungen des Provitamins A bei dessen lokaler Anwendung am Auge , Klin. Wchnschr. 13:918, 1934. 5. Towbin, B. G.: Ein Versuch der Carotinverwendung bei Hornhautverpflanzung , Ztschr. f. Augenh. 88:107, 1936. 6. Villard, H.; Viallefont, H., and Diacono, E.: Greffe de la cornée chez le lapin et vitamine A , Arch. Soc. d. sc. méd. et biol. de Montpellier 16:423, 1935. 7. Pashkovskij, V. M.: Effect of Carotene in Certain External Diseases of the Eye , Sovet. vestnik oftal. 7:500, 1935. 8. Meshcherskij, N. N.: Carotene in the Therapy of Herpetic Keratitis , Vestnik oftal. 10:419, 1937. 9. Stevenson, E.: Cod Liver Oil as a Local Treatment for External Affections of the Eyes , Brit. J. Ophth. 20:416, 1936.Crossref 10. Federici, E.: Le vitamine A e D nei processi di riparazione della cornea (studio sperimentale) , Boll. d'ocul. 16:357, 1937. 11. Rinaldi, S.: Le vitamine A e D nel trattamento locale di lesioni corneali (ricerche sperimentali e cliniche) , Ann. di ottal. e clin. ocul. 64:505, 1936. 12. Clausen: Demonstrationen (case 23) , Klin. Monatsbl. f. Augenh. 96:524, 1936. 13. Romeick, in discussion on Clausen, p. 526. 14. Villard, H. ; Viallefont, H., and Diacono, E. : Kératite ulcéreuse trophique guérie par vitaminothérapie locale , Arch. Soc. d. sc. méd. et biol. de Montpellier 16:302, 1935. 15. Heinsius, E.: Experimentelle Untersuchungen über den Einfluss des Vitamin A auf die Regeneration des Hornhautepithels , Arch. f. Ophth. 136:103, 1937 16. Lokale Verwendung von Vitamin-A-haltigen Salben in der Augenheilkunde , Klin. Monatsbl. f. Augenh. 98:246, 1937. 17. Viallefont, H., and Diacono, E. : Le rôle des vitamines en ophthalmologie , Arch. d'opht. 52:723, 1935. 18. Vanýsek, J.: Bedeutung des Vitamins A bei der Regeneration von Hornhautgewebe , Českoslov. oftal. 3:189, 1937. 19. Kentgens, S. K.: Ueber Vitamin-A-Therapie bei Hornhauterkrankungen , Ophthalmologica 96:3, 1938.Crossref 20. This product is prepared by Messrs. Gedeon Richter, Ltd., Budapest. 21. (a) Horn, Z., and Sándor, I.: Local Application of Vitamin A in Therapy of Wounds , Orvosi hetil. 78:261, 1934. 22. (b) Sándor, I.: Vitamin A (Vulnovitan) in the Local Treatment of Wounds , Orvosi hetil. 80:505, 1936. 23. Ferenczy, Z., cited by Sándor.16b 24. von Grósz, S.: Short-Wave Therapy in Ophthalmology , Orvosképzés 27: 94, 1937. 25. von Grósz, S.: Bedeutung der B-Vitamine in der Augenheilkunde , Arch. f. Ophth. 140:149, 1939. 26. Mellanby, E.: Durch mangelhafte Ernährung bedingte Erkrankungen des Nervensystems , Schweiz. med. Wchnschr. 67:349, 1936. 27. Hanke, V.: Die degenerativen und neurotrophischen Hornhauterkrankungen , Zentralbl. f. d. ges. Ophth. 36:465, 1936. 28. von Grósz, S.: Aetiologie und Therapie der Keratoconjunctivitis sicca , Klin. Monatsbl. f. Augenh. 97:472, 1936. 29. Cerise, L., and Thurel, R.: L'anesthésie pathologique de la cornée , Tours. Arrault & Cie, 1931. 30. Martin, P.: Effects of Irradiation of the Eye by Radium , Tr. Ophth. Soc. U. Kingdom 53:246, 1933.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Nov 1, 1939

References