ORIGINAL ARTICLE Local Steroid Injection via the Cricothyroid Membrane in Patients With a Vocal Nodule Sang-Hyuk Lee, MD, PhD; Jang-Ok Yeo, MD; Jeong-Im Choi, SLP; Hee-Jin Jin; Jin-Pyeong Kim, MD, PhD; Seung-Hoon Woo, MD; Sung-Min Jin, MD, PhD Objective: To analyze the usefulness and safety of a ste- Results: The nodules disappeared in 35 patients by the roid injection into vocal nodules via the cricothyroid mem- fourth week after the injection (44%), and 39 patients showed improvement (49%). Jitter, shimmer, maxi- brane. Local administration of steroid directly into the mum phonation time, and mean voice handicap index larynx has been reported in many laryngeal diseases with also improved significantly after the steroid injection different methods. (P.05 for all). Six patients with voice-related occupa- tions showed improvement at the second week (8%), but Design: Prospective case series at an academic tertiary the nodules had recurred after 4 weeks. Four patients ex- care hospital. perienced mild vocal fold atrophy, and 2 patients showed a white plaque formation on the vocal fold that resolved Patients: Eighty patients with vocal nodules were en- spontaneously 1 to 2 months after the injection. rolled between December 2008 and May 2010. Conclusions: A local steroid injection
JAMA Otolaryngology - Head & Neck Surgery – American Medical Association
Published: Oct 1, 2011
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