Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

LIVER EXTRACT THERAPY IN CIRRHOSIS OF THE LIVER: RELATION OF LIVER DYSFUNCTION TO NONSTORAGE OF ANTI-ANEMIC SUBSTANCE IN PRODUCING A BLOOD PICTURE RESEMBLING PERNICIOUS ANEMIA IN A PATIENT SECRETING FREE HYDROCHLORIC ACID

LIVER EXTRACT THERAPY IN CIRRHOSIS OF THE LIVER: RELATION OF LIVER DYSFUNCTION TO NONSTORAGE OF... Abstract The following case is reported in the hope that it may possibly throw new light on a group of patients who have been described as having a blood picture resembling that of pernicious anemia, but who have the ability to secrete hydrochloric acid in their stomachs. REPORT OF A CASE History. —R. M., a white man, aged 58, was admitted to the University Hospital on Oct. 27, 1931, complaining chiefly of "pain in the abdomen." Three months previously, he first noted a dragging and generalized discomfort in the abdomen below the umbilicus. This sensation became progressively worse and after nine weeks nausea developed. The pain was not related to the intake of food. Although the patient did not go to bed because of the pain, it was necessary for him to stop working. One week before admission, he noted that his stools were black and watery; he thought that this References 1. Bethell, F. H., and Goldhamer, S. M.: Standards for Maximum Reticulocyte Values Following Ventriculin and Intravenous Liver Extract Therapy in Pernicous Anemia , Am. J. M. Sc. 186:480 ( (Oct.) ) 1933.Crossref 2. Castle, W. B.: Observations on the Etiologic Relationship of Achylia Gastrica to Pernicious Anemia , Am. J. M. Sc. 178:748 ( (Dec.) ) 1929.Crossref 3. Strauss, M. B., and Castle, W. B.: The Nature of the Extrinsic Factor of the Deficiency State in Pernicious Anemia and in Related Macrocytic Anemias , New England J. Med. 207:55 ( (July 14) ) 1932.Crossref 4. Sturgis, C. C., and Isaacs, R.: Desiccated Stomach in the Treatment of Pernicious Anemia , J. A. M. A. 93:747 ( (Sept. 7) ) 1929.Crossref 5. Minot, G. R., and Murphy, W. P.: Treatment of Pernicious Anemia by a Special Diet , J. A. M. A. 87:470 ( (Aug. 14) ) 1926.Crossref 6. Richter, O., Ivy, A. C., and Kim, M. S.: Action of Human "Pernicious Anemia Liver Extract," Proc. Soc. Exper. Biol. & Med. 29:1093 ( (June) ) 1932. 7. Castle, W. B., Heath, C. W., and Strauss, M. B.: Observations on the Etiologic Relationship of Achylia Gastrica to Pernicious Anemia , Am. J. M. Sc. 182:741 ( (Dec.) ) 1931. 8. Holler, G., and Kudelka, O.: Resultate von Bestimmungen des Erythrozytendurchmessers beim Menschen unter physiologischen und pathologischen Verhältnissen , Folia haemat. 35:197 ( (Nov.) ) 1928. 9. Cheney, G., and Niemand, F.: The Treatment of Secondary Anemia with "Secondary Anemia Liver Extract" and Iron , Am. J. M. Sc. 184:314 ( (Sept.) ) 1932. 10. Masina, N.: Das Blutbild bei Leberzirrhose mit besonderer Berücksichtigung der Monozytengranulation , Folia haemat. 46:335 ( (March) ) 1932. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

LIVER EXTRACT THERAPY IN CIRRHOSIS OF THE LIVER: RELATION OF LIVER DYSFUNCTION TO NONSTORAGE OF ANTI-ANEMIC SUBSTANCE IN PRODUCING A BLOOD PICTURE RESEMBLING PERNICIOUS ANEMIA IN A PATIENT SECRETING FREE HYDROCHLORIC ACID

Archives of Internal Medicine , Volume 53 (1) – Jan 1, 1934

Loading next page...
 
/lp/american-medical-association/liver-extract-therapy-in-cirrhosis-of-the-liver-relation-of-liver-FlztJ0APIP
Publisher
American Medical Association
Copyright
Copyright © 1934 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1934.00160070059005
Publisher site
See Article on Publisher Site

Abstract

Abstract The following case is reported in the hope that it may possibly throw new light on a group of patients who have been described as having a blood picture resembling that of pernicious anemia, but who have the ability to secrete hydrochloric acid in their stomachs. REPORT OF A CASE History. —R. M., a white man, aged 58, was admitted to the University Hospital on Oct. 27, 1931, complaining chiefly of "pain in the abdomen." Three months previously, he first noted a dragging and generalized discomfort in the abdomen below the umbilicus. This sensation became progressively worse and after nine weeks nausea developed. The pain was not related to the intake of food. Although the patient did not go to bed because of the pain, it was necessary for him to stop working. One week before admission, he noted that his stools were black and watery; he thought that this References 1. Bethell, F. H., and Goldhamer, S. M.: Standards for Maximum Reticulocyte Values Following Ventriculin and Intravenous Liver Extract Therapy in Pernicous Anemia , Am. J. M. Sc. 186:480 ( (Oct.) ) 1933.Crossref 2. Castle, W. B.: Observations on the Etiologic Relationship of Achylia Gastrica to Pernicious Anemia , Am. J. M. Sc. 178:748 ( (Dec.) ) 1929.Crossref 3. Strauss, M. B., and Castle, W. B.: The Nature of the Extrinsic Factor of the Deficiency State in Pernicious Anemia and in Related Macrocytic Anemias , New England J. Med. 207:55 ( (July 14) ) 1932.Crossref 4. Sturgis, C. C., and Isaacs, R.: Desiccated Stomach in the Treatment of Pernicious Anemia , J. A. M. A. 93:747 ( (Sept. 7) ) 1929.Crossref 5. Minot, G. R., and Murphy, W. P.: Treatment of Pernicious Anemia by a Special Diet , J. A. M. A. 87:470 ( (Aug. 14) ) 1926.Crossref 6. Richter, O., Ivy, A. C., and Kim, M. S.: Action of Human "Pernicious Anemia Liver Extract," Proc. Soc. Exper. Biol. & Med. 29:1093 ( (June) ) 1932. 7. Castle, W. B., Heath, C. W., and Strauss, M. B.: Observations on the Etiologic Relationship of Achylia Gastrica to Pernicious Anemia , Am. J. M. Sc. 182:741 ( (Dec.) ) 1931. 8. Holler, G., and Kudelka, O.: Resultate von Bestimmungen des Erythrozytendurchmessers beim Menschen unter physiologischen und pathologischen Verhältnissen , Folia haemat. 35:197 ( (Nov.) ) 1928. 9. Cheney, G., and Niemand, F.: The Treatment of Secondary Anemia with "Secondary Anemia Liver Extract" and Iron , Am. J. M. Sc. 184:314 ( (Sept.) ) 1932. 10. Masina, N.: Das Blutbild bei Leberzirrhose mit besonderer Berücksichtigung der Monozytengranulation , Folia haemat. 46:335 ( (March) ) 1932.

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Jan 1, 1934

References