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Lesions Mistaken for Malignant Melanoma of the Iris

Lesions Mistaken for Malignant Melanoma of the Iris Abstract In many instances enucleation of an eye that is erroneously thought to contain a malignant melanoma is a tragic loss for the patient. In a recent retrospective study it was shown that 19% of eyes removed because of a diagnosis of malignant melanoma of the choroid or posterior ciliary body, on the basis of an ophthalmoscopically visible lesion, were found on pathologic examination1 to harbor a lesion other than malignant melanoma. The rather startling observation that one in every five eyes with an ophthalmoscopically visible lesion diagnosed clinically as malignant melanoma proves to be an instance of erroneous diagnosis led us to investigate the incidence of incorrect clinical diagnosis in the case of malignant melanoma of the iris. These tumors are less common than malignant melanomas of the ciliary body and choroid, and the clinician has even less experience in dealing with them than with those that involve the References 1. Ferry, A. P.: Lesions Mistaken for Malignant Melanoma of Posterior Uvea , Arch Ophthal 72: 463-469, 1964.Crossref 2. Dunphy, E. B., et al: Diagnosis and Management of Intraocular Melanomas: Symposium , Trans Amer Acad Ophthal Otolaryng 62:517-555, 1958. 3. Reese, A. B.: Tumors of Eye , ed 2, New York: Hoeber Medical Division of Harper & Row Publishers, Inc., 1963. 4. Rones, B., and Zimmerman, L. E.: Prognosis of Primary Tumors of Iris Treated by Iridectomy , Arch Ophthal 60:193-205, 1958.Crossref 5. Ferry, A. P., and Zimmerman, L. E.: Black Cornea: Complication of Topical Use of Epinephrine , Amer J Ophthal 58:205-210, 1964. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Lesions Mistaken for Malignant Melanoma of the Iris

Archives of Ophthalmology , Volume 74 (1) – Jul 1, 1965

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Publisher
American Medical Association
Copyright
Copyright © 1965 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1965.00970040011004
Publisher site
See Article on Publisher Site

Abstract

Abstract In many instances enucleation of an eye that is erroneously thought to contain a malignant melanoma is a tragic loss for the patient. In a recent retrospective study it was shown that 19% of eyes removed because of a diagnosis of malignant melanoma of the choroid or posterior ciliary body, on the basis of an ophthalmoscopically visible lesion, were found on pathologic examination1 to harbor a lesion other than malignant melanoma. The rather startling observation that one in every five eyes with an ophthalmoscopically visible lesion diagnosed clinically as malignant melanoma proves to be an instance of erroneous diagnosis led us to investigate the incidence of incorrect clinical diagnosis in the case of malignant melanoma of the iris. These tumors are less common than malignant melanomas of the ciliary body and choroid, and the clinician has even less experience in dealing with them than with those that involve the References 1. Ferry, A. P.: Lesions Mistaken for Malignant Melanoma of Posterior Uvea , Arch Ophthal 72: 463-469, 1964.Crossref 2. Dunphy, E. B., et al: Diagnosis and Management of Intraocular Melanomas: Symposium , Trans Amer Acad Ophthal Otolaryng 62:517-555, 1958. 3. Reese, A. B.: Tumors of Eye , ed 2, New York: Hoeber Medical Division of Harper & Row Publishers, Inc., 1963. 4. Rones, B., and Zimmerman, L. E.: Prognosis of Primary Tumors of Iris Treated by Iridectomy , Arch Ophthal 60:193-205, 1958.Crossref 5. Ferry, A. P., and Zimmerman, L. E.: Black Cornea: Complication of Topical Use of Epinephrine , Amer J Ophthal 58:205-210, 1964.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Jul 1, 1965

References