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Leptospirosis as a Cause of Uveitis

Leptospirosis as a Cause of Uveitis Abstract To the Editor.—Although Rosenbaum showed clearly that an evaluation for systemic disease in a patient with uveitis is useful, no specific diagnosis could be made in a quarter of his patients. The cause remained undefined in over half the patients reported in another large study.2 Adding leptospirosis to the list of causes of uveal tract inflammation could perhaps improve the ability to determine a specific cause. This disease remains a major public health problem in parts of the developing world, and is frequently underdiagnosed in the United States: in one series only 17% of 483 proven cases were initially thought to be leptospirosis.3 The precise incidence of uveitis in leptospirosis is unknown, but has been reported to range from 10% to 44%.4 The anterior uveal tract is usually affected 4 to 8 months after initial disease symptoms appear, at a time when other clinical features have References 1. Rosenbaum JT. Uveitis: an internist's view . Arch Intern Med . 1989;149:1173-1176.Crossref 2. Perkins ES, Folk J. Uveitis in London and Iowa . Ophthalmologica . 1984;189:36-40.Crossref 3. Heath CW Jr, Alexander AD, Galton MM. Leptospirosis in the United States . N Engl J Med . 1965;273:857-922.Crossref 4. Gsell 0, Wiesmann E. Leptospirosen Medizin . Bern, Switzerland: Hans Huber Verlag; 1950. 5. Feigin RD, Anderson DC. Human leptospirosis . CRC Crit Rev Clin Lab Sci . 1975;5:413-467.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Leptospirosis as a Cause of Uveitis

Archives of Internal Medicine , Volume 150 (5) – May 1, 1990

Leptospirosis as a Cause of Uveitis

Abstract

Abstract To the Editor.—Although Rosenbaum showed clearly that an evaluation for systemic disease in a patient with uveitis is useful, no specific diagnosis could be made in a quarter of his patients. The cause remained undefined in over half the patients reported in another large study.2 Adding leptospirosis to the list of causes of uveal tract inflammation could perhaps improve the ability to determine a specific cause. This disease remains a major public health problem in parts of...
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Publisher
American Medical Association
Copyright
Copyright © 1990 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1990.00390170152044
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.—Although Rosenbaum showed clearly that an evaluation for systemic disease in a patient with uveitis is useful, no specific diagnosis could be made in a quarter of his patients. The cause remained undefined in over half the patients reported in another large study.2 Adding leptospirosis to the list of causes of uveal tract inflammation could perhaps improve the ability to determine a specific cause. This disease remains a major public health problem in parts of the developing world, and is frequently underdiagnosed in the United States: in one series only 17% of 483 proven cases were initially thought to be leptospirosis.3 The precise incidence of uveitis in leptospirosis is unknown, but has been reported to range from 10% to 44%.4 The anterior uveal tract is usually affected 4 to 8 months after initial disease symptoms appear, at a time when other clinical features have References 1. Rosenbaum JT. Uveitis: an internist's view . Arch Intern Med . 1989;149:1173-1176.Crossref 2. Perkins ES, Folk J. Uveitis in London and Iowa . Ophthalmologica . 1984;189:36-40.Crossref 3. Heath CW Jr, Alexander AD, Galton MM. Leptospirosis in the United States . N Engl J Med . 1965;273:857-922.Crossref 4. Gsell 0, Wiesmann E. Leptospirosen Medizin . Bern, Switzerland: Hans Huber Verlag; 1950. 5. Feigin RD, Anderson DC. Human leptospirosis . CRC Crit Rev Clin Lab Sci . 1975;5:413-467.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: May 1, 1990

References