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Leiner's Disease

Leiner's Disease Abstract Generalized exfoliative eruptions of infancy, though observed only infrequently in America, are nevertheless of interest because of continuing confusion as to the existence and nature of Leiner's "erythrodermia desquamativa." In the experience of Leiner and other European pediatricians this disease was observed with frequency, but dermatoses of all types were then commoner, Leiner having remarked that children without some eruption were the exception. Many experienced American dermatologists have never made a diagnosis of Leiner's disease. Cole, Hodges, and Silver1 discussed the subject several years ago, and more recently Crotty,2 in Military Service, reported four instances observed in Europe but (presumably) occurring in infants born of American parents. My interest in this disorder was activated by observance of a patient on the Pediatric Service of the University of Minnesota Hospitals. Report of a Case* A boy, born Nov. 1, 1955, of a diabetic References 1. This case is presented by courtesy of the Department of Pediatrics, University of Minnesota, Dr. John A. Anderson, Director. 2. Cole, H. N., Jr.; Hodges, R. G., and Silver, F. F.: Relationship between Ritter's and Leiner's Diseases , A. M. A. Arch. Dermat. & Syph. 70:443, 1954. 3. Crotty, R. Q.: Erythroderma Desquamativum (Leiner's Disease) , A. M. A. Arch. Dermat. 71:587, 1955. 4. Leiner, C.: Eczema universale seborrhoicum, case presentation before Vienna Dermatologic Society in 1903, cited by Leiner,6 p. 181. 5. Leiner, C.: Erythroderma desquamativa, eine eigentartige universelle Dermatose bei Brustkinder , Wien. med. Wchnschr. 57:2459, 1907. 6. Leiner, C.: Erythrodermia Desquamativa (Universal Dermatitis of Children at the Breast) , Brit. J. Child. Dis. 5:244, 1908. 7. Leiner, C.: Über Erythroderma desquamativa, eine eigentartige universelle Dermatose der Brustkinder , Arch. Dermat. u. Syph. 89:163, 1908. 8. Leiner, C.: Hautkrankheiten im Säuglingsalter, in Jadassohn's Handbuch der Haut- und Geschlechtskrankheiten , Vol. 14, Berlin, SpringerVerlag, 1930, p. 459. 9. Moro, E.: Ekzema infantum und Dermatitis seborrhoides , Berlin, Springer-Verlag, 1932. 10. Winkler, F., and Unna, P. G.: Das seborrhoische Ekzem, in Jadassohn's Handbuch der Haut- und Geschlechtskrankheiten , Vol. 6, Berlin, Springer-Verlag, 1927, p. 446. 11. Kreibich, C.: Eczema seborrhoicum, in Jadassohn's Handbuch der Haut- und Geschlechtstkrankheiten , Vol. 6, Berlin, Springer-Verlag, 1927, p. 136. 12. Hill, L. W.: Erythroderma desquamativa , J. Pediat. 4:436, 1934. 13. Hill, L. W.: The Treatment of Eczema in Infants and Children , St. Louis, The C. V. Mosby Company, 1956. 14. Gans, O., and Steigleder, G. K.: Histologie der Hautkrankheiten , Ed. 2, Berlin, Springer-Verlag, 1955, Vol. 1, p. 352. 15. Ivady, G.; Koltay, M., and Ebery, P.: Examinations Referring to the Pathogenesis of Leiner's Disease , Orv. Hetil. , 2:41, 1955 16. abstracted, Excerpta Med. XIII , 10:349, 1956. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1957 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1957.01550170097016
Publisher site
See Article on Publisher Site

Abstract

Abstract Generalized exfoliative eruptions of infancy, though observed only infrequently in America, are nevertheless of interest because of continuing confusion as to the existence and nature of Leiner's "erythrodermia desquamativa." In the experience of Leiner and other European pediatricians this disease was observed with frequency, but dermatoses of all types were then commoner, Leiner having remarked that children without some eruption were the exception. Many experienced American dermatologists have never made a diagnosis of Leiner's disease. Cole, Hodges, and Silver1 discussed the subject several years ago, and more recently Crotty,2 in Military Service, reported four instances observed in Europe but (presumably) occurring in infants born of American parents. My interest in this disorder was activated by observance of a patient on the Pediatric Service of the University of Minnesota Hospitals. Report of a Case* A boy, born Nov. 1, 1955, of a diabetic References 1. This case is presented by courtesy of the Department of Pediatrics, University of Minnesota, Dr. John A. Anderson, Director. 2. Cole, H. N., Jr.; Hodges, R. G., and Silver, F. F.: Relationship between Ritter's and Leiner's Diseases , A. M. A. Arch. Dermat. & Syph. 70:443, 1954. 3. Crotty, R. Q.: Erythroderma Desquamativum (Leiner's Disease) , A. M. A. Arch. Dermat. 71:587, 1955. 4. Leiner, C.: Eczema universale seborrhoicum, case presentation before Vienna Dermatologic Society in 1903, cited by Leiner,6 p. 181. 5. Leiner, C.: Erythroderma desquamativa, eine eigentartige universelle Dermatose bei Brustkinder , Wien. med. Wchnschr. 57:2459, 1907. 6. Leiner, C.: Erythrodermia Desquamativa (Universal Dermatitis of Children at the Breast) , Brit. J. Child. Dis. 5:244, 1908. 7. Leiner, C.: Über Erythroderma desquamativa, eine eigentartige universelle Dermatose der Brustkinder , Arch. Dermat. u. Syph. 89:163, 1908. 8. Leiner, C.: Hautkrankheiten im Säuglingsalter, in Jadassohn's Handbuch der Haut- und Geschlechtskrankheiten , Vol. 14, Berlin, SpringerVerlag, 1930, p. 459. 9. Moro, E.: Ekzema infantum und Dermatitis seborrhoides , Berlin, Springer-Verlag, 1932. 10. Winkler, F., and Unna, P. G.: Das seborrhoische Ekzem, in Jadassohn's Handbuch der Haut- und Geschlechtskrankheiten , Vol. 6, Berlin, Springer-Verlag, 1927, p. 446. 11. Kreibich, C.: Eczema seborrhoicum, in Jadassohn's Handbuch der Haut- und Geschlechtstkrankheiten , Vol. 6, Berlin, Springer-Verlag, 1927, p. 136. 12. Hill, L. W.: Erythroderma desquamativa , J. Pediat. 4:436, 1934. 13. Hill, L. W.: The Treatment of Eczema in Infants and Children , St. Louis, The C. V. Mosby Company, 1956. 14. Gans, O., and Steigleder, G. K.: Histologie der Hautkrankheiten , Ed. 2, Berlin, Springer-Verlag, 1955, Vol. 1, p. 352. 15. Ivady, G.; Koltay, M., and Ebery, P.: Examinations Referring to the Pathogenesis of Leiner's Disease , Orv. Hetil. , 2:41, 1955 16. abstracted, Excerpta Med. XIII , 10:349, 1956.

Journal

A.M.A. Archives of DermatologyAmerican Medical Association

Published: May 1, 1957

References