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LATE EFFECTS OF CHILDHOOD CANCER

LATE EFFECTS OF CHILDHOOD CANCER This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Twenty-five years ago the outlook for children with cancer was poor. Fewer than 25% survived for three or more years. Rare exceptions to this grim experience included children with localized and totally resected Wilms' tumor and neuroblastoma and with stage I Hodgkin's disease, and the occasional patient with acute lymphoblastic leukemia (ALL). Major advances in diagnosis and treatment have increased cure rates to over 50% for all major childhood cancers except acute nonlymphoblastic leukemia, malignant brain tumors, and selected metastatic (stage IV) solid tumors. Major contributors to this success are the effective use of multimodality therapy, improved supportive care, and, more recently, the identification of clinical and biological prognostic factors that determine the relative intensity and duration of treatment. It has been estimated that by 1990, 0.1% of all adults (1:1000) will be cured patients who had had pediatric cancer. Thus, physicians caring for children, adolescents, and young adults should be http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

LATE EFFECTS OF CHILDHOOD CANCER

LATE EFFECTS OF CHILDHOOD CANCER

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Twenty-five years ago the outlook for children with cancer was poor. Fewer than 25% survived for three or more years. Rare exceptions to this grim experience included children with localized and totally resected Wilms' tumor and neuroblastoma and with stage I Hodgkin's disease, and the occasional patient with acute lymphoblastic leukemia...
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Publisher
American Medical Association
Copyright
Copyright © 1988 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1988.02150110025011
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Twenty-five years ago the outlook for children with cancer was poor. Fewer than 25% survived for three or more years. Rare exceptions to this grim experience included children with localized and totally resected Wilms' tumor and neuroblastoma and with stage I Hodgkin's disease, and the occasional patient with acute lymphoblastic leukemia (ALL). Major advances in diagnosis and treatment have increased cure rates to over 50% for all major childhood cancers except acute nonlymphoblastic leukemia, malignant brain tumors, and selected metastatic (stage IV) solid tumors. Major contributors to this success are the effective use of multimodality therapy, improved supportive care, and, more recently, the identification of clinical and biological prognostic factors that determine the relative intensity and duration of treatment. It has been estimated that by 1990, 0.1% of all adults (1:1000) will be cured patients who had had pediatric cancer. Thus, physicians caring for children, adolescents, and young adults should be

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Nov 1, 1988

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