Abstract • Eighty-seven patients (35 with primary open-angle glaucoma, 20 with angle-closure glaucoma, and 32 controls) underwent HLA typing of peripheral lymphocytes. Sixteen specificities were detected at the A locus, 19 at the B locus, and four at the C locus. No significant differences were found between patients with either type of glaucoma and control patients. References 1. McDevitt HO, Bodmer WF: HL-A, immune response genes, and disease . Lancet 1:1269-1275, 1974.Crossref 2. Ritzmann SE: HLA patterns and disease associations . JAMA 236:2305-2309, 1976.Crossref 3. Sasazuki T, McDevitt HO, Grumet FC: The association between genes in the major histocompatibility complex and disease susceptibility . Annu Rev Med 28:425-452, 1977.Crossref 4. Aviner Z, Henley WL, Fotino M, et al: Histocompatibility (HL-A) antigens and primary open-angle glaucoma . Tissue Antigens 7:193-200, 1976.Crossref 5. Shin DH, Becker B, Waltman SR, et al: The prevalence of HLA-B12 and HLA-B7 antigens in primary open-angle glaucoma . Arch Ophthalmol 95:224-225, 1977.Crossref 6. Grabner G, Mayr WR: Histokompatibilitätsantigene (HLA-Antigene) und Offenwinkel-Glaukom . Albrecht von Graefes Arch Klin Ophthalmol 202:75-79, 1977.Crossref 7. Fotino M, Merson E, Allen FH: Instant lymphocytes . Vox Sang 21:469-470, 1971.Crossref 8. Svejgaard A, Jersild C, Staub Nielsen L, et al: HL-A antigens and disease: Statistical and genetical considerations . Tissue Antigens 4:95-105, 1974.Crossref 9. Walsh FS, Crumpton MJ: Orientation of cell-surface antigens in the lipid bilayer of lymphocyte plasma membrane . Nature 269:307-311, 1977.Crossref 10. Suciu-Foca N, Rubinstein P: Genetic fine structure of the HLA region . Transplant Proc 9:385-391, 1977. 11. Bach FH, Van Rood JJ: The major histocompatibility complex—genetics and biology . N Engl J Med 295:806-813, 1976.Crossref 12. Woolf B: On estimating the relation between blood group and disease . Ann Hum Genet 19:251-253, 1955.Crossref 13. Becker B, Shin DH: HLA antigens and primary open-angle glaucoma in black Americans . Invest Ophthalmol 16:175-176, 1977. 14. Shin DH, Becker B: The prognostic value of HLA-B12 and HLA-B7 antigens in patients with increased intraocular pressure . Am J Ophthalmol 82:871-874, 1976. 15. Becker B, Shin DH, Palmberg PF, et al: HLA antigens and corticosteroid response . Science 194:1427-1430, 1976.Crossref 16. Becker B, Palmberg PF, Shin DH: Glucocorticoid responsiveness associated with HLA-B12 . Invest Ophthalmol 16:61-63, 1977. 17. Shin DH, Kass MA, Becker B: HLA-B12 and intraocular pressure response to topical epinephrine. Presented at the Association for Research in Vision and Ophthalmology, Sarasota, Fla, May 1977. 18. Shin DH, Kass MA, Becker B: The association of HLA-B7 and HLA-B12 antigens with cup/disk ratio, family history of glaucoma, and intraocular pressure . Am J Ophthalmol 83:347-349, 1977. 19. Shin DH, Becker B: HLA-A11 and HLABw35 and resistance to glaucoma in white patients with ocular hypertension . Arch Ophthalmol 95:423-424, 1977.Crossref 20. Rosenberg LE, Kidd KK: HLA and disease susceptibility: A primer . N Engl J Med 297:1060-1063, 1977.Crossref 21. Becker B, Unger HH, Coleman SL, et al: Plasma cells and gamma-globulin in trabecular meshwork of eyes with primary open-angle glaucoma . Arch Ophthalmol 70:38-41, 1963.Crossref 22. Felberg NT, Leon AS, Gasparini J, et al: A comparison of antinuclear antibodies of DNAbinding antibodies in chronic open-angle glaucoma . Invest Ophthalmol 16:757-760, 1977.
Archives of Ophthalmology – American Medical Association
Published: Dec 1, 1978
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