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Keratosis Blennorrhagica (Reiter's Disease?) and Its Treatment

Keratosis Blennorrhagica (Reiter's Disease?) and Its Treatment Abstract The keratotic skin lesions of keratosis blennorrhagica, which usually follow gonorrheal urethritis and polyarthritis, have been treated with many drugs, but none has found universal approval. In recent years the antibiotics and the corticosteroid hormones have been used with varying success, ranging from complete cure to little or no effect whatsoever. It is difficult to evaluate the true benefit of therapeutic agents in keratosis blennorrhagica because (1) the condition is usually self-limited and (2) the disorder is encountered too infrequently for any investigator to have an adequate number of control cases. The purpose of this paper is to review some of the literature on the treatment of keratosis blennorrhagica and to report our experience with the use of the antibiotics and corticosteroid hormones. References 1. Ladany, E., and Hughes, J. D.: Etiological Considerations of Keratosis Blennorrhagica , Arch. Dermat. & Syph. 54:150, 1946. 2. Lever, W. F., and Crawford, G. M.: Keratosis Blennorrhagica Without Gonorrhea (Reiter's Disease?) , Arch. Dermat. & Syph. 49:389, 1944. 3. Baxter, C. R.: Reiter's Disease , Brit. M. J. 2:858, 1946. 4. Epstein, E.: Reiter's Disease: A Comparison with Keratosis Blennorrhagica and with Psoriasis Arthropathica , Arch. Dermat. & Syph. 56:191, 1947. 5. Peters, J. H.: Reiter's Syndrome with Keratotic Dermatitis: Report of a Case , Arch. Dermat. & Syph. 59:217, 1949. 6. Hall, W. H., and Finegold, S.: A Study of 23 Cases of Reiter's Syndrome , Ann. Int. Med. 38:533, 1953. 7. Cameron, J. M.: Keratodermia Blennorrhagica , Brit. J. Ven. Dis. 32:7, 1956. 8. Spencer, G. A.: Keratosis Blennorrhagica , Arch. Dermat. & Syph. 54:455, 1946. 9. Carr, J. L., and Friedman, M.: Keratodermia Blennorrhagicum: Report of a Case with Autopsy , Am. J. Path. 20:709, 1944. 10. Emmet, R.: Keratosis Blennorrhagica: Its Response to Penicillin , Arch. Dermat. & Syph. 53:278, 1946. 11. Miale, J. B., and Singletary, W. V.: Cutaneous Manifestations of Gonococcic Infection , Arch. Dermat. & Syph. 57:151, 1948. 12. Chinn, B. D.; Putnam, L. E.; Taggart, S. R., and Hervich, R. P.: The Treatment of Gonorrhea with Streptomycin , Am. J. Syph. 31:268, 1947. 13. Thompson, R. G.; White, C. B., and Hailey, H.: Keratosis Blennorrhagica: Response to Streptomycin: Report of a Case , Arch. Dermat. & Syph. 59:284, 1949. 14. Shallard, B., and Kanee, B.: ACTH in the Treatment of Keratodermia Blennorrhagica , Canad. M. A. J. 68:561, 1953. 15. Myerson, R. M., and Katzenstein, L.: Keratosis Blennorrhagica Successfully Treated with Corticotropin (ACTH) , J. A. M. A. 149:838, 1952. 16. Ikejiani, O.: Keratosis Blennorrhagica: Report of 2 Cases Successfully Treated with Corticotropin (ACTH) , West African M. J. 4:196, 1955. 17. Schwarz, H., and Kingma, H.: Keratodermia Blennorrhagica Treated with Cortisone , Brit. J. Dermat. 64:388, 1952. 18. Beck, L.: Keratosis Blennorrhagica or Reiter's Syndrome? New York J. Med. 54:1801, 1954. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

Keratosis Blennorrhagica (Reiter's Disease?) and Its Treatment

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Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1959.01560170079012
Publisher site
See Article on Publisher Site

Abstract

Abstract The keratotic skin lesions of keratosis blennorrhagica, which usually follow gonorrheal urethritis and polyarthritis, have been treated with many drugs, but none has found universal approval. In recent years the antibiotics and the corticosteroid hormones have been used with varying success, ranging from complete cure to little or no effect whatsoever. It is difficult to evaluate the true benefit of therapeutic agents in keratosis blennorrhagica because (1) the condition is usually self-limited and (2) the disorder is encountered too infrequently for any investigator to have an adequate number of control cases. The purpose of this paper is to review some of the literature on the treatment of keratosis blennorrhagica and to report our experience with the use of the antibiotics and corticosteroid hormones. References 1. Ladany, E., and Hughes, J. D.: Etiological Considerations of Keratosis Blennorrhagica , Arch. Dermat. & Syph. 54:150, 1946. 2. Lever, W. F., and Crawford, G. M.: Keratosis Blennorrhagica Without Gonorrhea (Reiter's Disease?) , Arch. Dermat. & Syph. 49:389, 1944. 3. Baxter, C. R.: Reiter's Disease , Brit. M. J. 2:858, 1946. 4. Epstein, E.: Reiter's Disease: A Comparison with Keratosis Blennorrhagica and with Psoriasis Arthropathica , Arch. Dermat. & Syph. 56:191, 1947. 5. Peters, J. H.: Reiter's Syndrome with Keratotic Dermatitis: Report of a Case , Arch. Dermat. & Syph. 59:217, 1949. 6. Hall, W. H., and Finegold, S.: A Study of 23 Cases of Reiter's Syndrome , Ann. Int. Med. 38:533, 1953. 7. Cameron, J. M.: Keratodermia Blennorrhagica , Brit. J. Ven. Dis. 32:7, 1956. 8. Spencer, G. A.: Keratosis Blennorrhagica , Arch. Dermat. & Syph. 54:455, 1946. 9. Carr, J. L., and Friedman, M.: Keratodermia Blennorrhagicum: Report of a Case with Autopsy , Am. J. Path. 20:709, 1944. 10. Emmet, R.: Keratosis Blennorrhagica: Its Response to Penicillin , Arch. Dermat. & Syph. 53:278, 1946. 11. Miale, J. B., and Singletary, W. V.: Cutaneous Manifestations of Gonococcic Infection , Arch. Dermat. & Syph. 57:151, 1948. 12. Chinn, B. D.; Putnam, L. E.; Taggart, S. R., and Hervich, R. P.: The Treatment of Gonorrhea with Streptomycin , Am. J. Syph. 31:268, 1947. 13. Thompson, R. G.; White, C. B., and Hailey, H.: Keratosis Blennorrhagica: Response to Streptomycin: Report of a Case , Arch. Dermat. & Syph. 59:284, 1949. 14. Shallard, B., and Kanee, B.: ACTH in the Treatment of Keratodermia Blennorrhagica , Canad. M. A. J. 68:561, 1953. 15. Myerson, R. M., and Katzenstein, L.: Keratosis Blennorrhagica Successfully Treated with Corticotropin (ACTH) , J. A. M. A. 149:838, 1952. 16. Ikejiani, O.: Keratosis Blennorrhagica: Report of 2 Cases Successfully Treated with Corticotropin (ACTH) , West African M. J. 4:196, 1955. 17. Schwarz, H., and Kingma, H.: Keratodermia Blennorrhagica Treated with Cortisone , Brit. J. Dermat. 64:388, 1952. 18. Beck, L.: Keratosis Blennorrhagica or Reiter's Syndrome? New York J. Med. 54:1801, 1954.

Journal

A.M.A. Archives of DermatologyAmerican Medical Association

Published: May 1, 1959

References