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KERATODERMA CLIMACTERICUM (HAXTHAUSEN): HYPOESTROGENIC KERATODERMATITIS

KERATODERMA CLIMACTERICUM (HAXTHAUSEN): HYPOESTROGENIC KERATODERMATITIS Abstract Although not the first to describe a peculiar keratotic thickening of the palms and soles associated with the climacteric, Haxthausen1 in 1934 presented a clear description of the eruption and noted its association with other evidences of the climacteric. He applied the term keratoderma climactericum to a "distinct clinical picture consisting of circumscribed hyperkeratosis, mainly of the palms and soles, occurring in women in association with the climacteric and accompanied by various general signs and symptoms, of which obesity and arterial hypertension are those most frequently encountered." This disease had received little attention before Haxthausen's report and even now is not often considered. There have been a few reports of cases, but both the dermatologic textbooks and those on endocrine diseases have given it little attention. Dermatologists should be more familiar with this keratosis, first, because it is more common than is generally realized; second, because its presence indicates References 1. Haxthausen, H.: Keratoderma Climactericum , Brit. J. Dermat. 46:161, 1934.Crossref 2. Brooke, H. G.: Notes on Some Keratoses of the Palms and Soles , Brit. J. Dermat. 3:19, 1891. 3. Brooke, H. G.: Erythema Keratodes of Palms and Soles , Brit. J. Dermat. 3:335, 1891. 4. Dubreuilh, W.: Erythema Keratodes of the Palms and Soles , Brit. J. Dermat. 4:185, 1892.Crossref 5. Moncorps, C., in Jadassohn, J.: Handbuch der Haut- und Geschlechtskrankheiten , Berlin, Julius Springer, 1931, vol. 8, pt. (2) , p. 300. 6. Brunsting, L. A., in discussion on Becker, S. W., and Obermayer, M. E.: Keratoderma Climactericum , Arch. Dermat. & Syph. 36:646 ( (Sept.) ) 1937. 7. Engman, M. F., Jr., in discussion on Becker and Obermayer. 8. Weiss, R. S., in discussion on Becker and Obermayer. 9. Becker, S. W., and Obermayer, M. E.: Modern Dermatology and Syphilology , Philadelphia, J. B. Lippincott Company, 1940, p. 182. 10. Goldberg, L. C.: Keratoderma Climactericum , Arch. Dermat. & Syph. 40:67 ( (July) ) 1939. 11. Bishop, P. M. F., and Barber, H. W.: Keratoderma Climactericum (Haxthausen) Treated with Oestrone , Proc. Roy. Soc. Med. 30:738, 1937. 12. Wolf, J.: Keratoderma Climactericum , Arch. Dermat. & Syph. 43:731 ( (April) ) 1941. 13. Gans, O.: Histologie der Hautkrankheiten , Berlin, Julius Springer, 1925, vol. 1, p. 55. 14. Fox, H.: Standard Nomenclature of Disease , Arch. Dermat. & Syph. 46:534 ( (Oct.) ) 1942. 15. Becker, S. W.: Personal communication to the author. 16. Smith, M. S.: Lichen Simplex Chronicus (Neurodermatitis) of the Palms and Soles , Brit. J. Dermat. 54:255, 1942. 17. Barber, H. W.: Symmetrical Hyperkeratosis of the Palms and Soles , Brit. J. Dermat. 46:95, 1934. 18. Mierzecki: Keratoderma palmare et plantare hereditarium , Zentralbl. f. Haut- u. Geschlechtskr. 21:141, 1926. 19. Sutejec, G.: Klinik und Pathogenese der familiären symmetrischen Keratodermie , Zentralbl. f. Haut- u. Geschlechtskr. 24:798, 1927. 20. Olmsted, H. C.: Keratodermia Plantaris et Palmaris Congenitalis , Am. J. Dis. Child. 33:757 ( (May) ) 1927. 21. Henschen, C.: Ueber das Keratoderma senile volae manuum et plantae pedum und seine Heilung durch Perandren , Schweiz. med. Wchnschr. 70:690, 1940. 22. Bechet, P.: Keratosis Plantaris , Arch. Dermat. & Syph. 46:762 ( (Nov.) ) 1942. 23. MacKee, G. M., in discussion on Bechet. 24. Mussio-Fournier, J. C.: Kératodermie plantaire et palmaire chez une hypothyroïdienne , Bull. et mém. Soc. méd. d. hôp. de Paris 48:1236, 1932. 25. Niles, H. D.: A Case for Diagnosis (Keratoderma Palmare Symmetricum) , Arch. Dermat. & Syph. 34:1051 ( (Dec.) ) 1936. 26. Guy, W. H., and Jacob, F. M.: Keratoderma Plantare , Arch. Dermat. & Syph. 36:1285 ( (Dec.) ) 1937. 27. Cervino, J. M.; Bertolini, A., and Larrosa Helguera, R. A.: Keratodermias of the Hands and Feet and Thyroid Deficiency , Endocrinology 22:615, 1938. 28. Engman.6b 29. Weiss.6c http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

KERATODERMA CLIMACTERICUM (HAXTHAUSEN): HYPOESTROGENIC KERATODERMATITIS

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Publisher
American Medical Association
Copyright
Copyright © 1943 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1943.01510030023004
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Abstract

Abstract Although not the first to describe a peculiar keratotic thickening of the palms and soles associated with the climacteric, Haxthausen1 in 1934 presented a clear description of the eruption and noted its association with other evidences of the climacteric. He applied the term keratoderma climactericum to a "distinct clinical picture consisting of circumscribed hyperkeratosis, mainly of the palms and soles, occurring in women in association with the climacteric and accompanied by various general signs and symptoms, of which obesity and arterial hypertension are those most frequently encountered." This disease had received little attention before Haxthausen's report and even now is not often considered. There have been a few reports of cases, but both the dermatologic textbooks and those on endocrine diseases have given it little attention. Dermatologists should be more familiar with this keratosis, first, because it is more common than is generally realized; second, because its presence indicates References 1. Haxthausen, H.: Keratoderma Climactericum , Brit. J. Dermat. 46:161, 1934.Crossref 2. Brooke, H. G.: Notes on Some Keratoses of the Palms and Soles , Brit. J. Dermat. 3:19, 1891. 3. Brooke, H. G.: Erythema Keratodes of Palms and Soles , Brit. J. Dermat. 3:335, 1891. 4. Dubreuilh, W.: Erythema Keratodes of the Palms and Soles , Brit. J. Dermat. 4:185, 1892.Crossref 5. Moncorps, C., in Jadassohn, J.: Handbuch der Haut- und Geschlechtskrankheiten , Berlin, Julius Springer, 1931, vol. 8, pt. (2) , p. 300. 6. Brunsting, L. A., in discussion on Becker, S. W., and Obermayer, M. E.: Keratoderma Climactericum , Arch. Dermat. & Syph. 36:646 ( (Sept.) ) 1937. 7. Engman, M. F., Jr., in discussion on Becker and Obermayer. 8. Weiss, R. S., in discussion on Becker and Obermayer. 9. Becker, S. W., and Obermayer, M. E.: Modern Dermatology and Syphilology , Philadelphia, J. B. Lippincott Company, 1940, p. 182. 10. Goldberg, L. C.: Keratoderma Climactericum , Arch. Dermat. & Syph. 40:67 ( (July) ) 1939. 11. Bishop, P. M. F., and Barber, H. W.: Keratoderma Climactericum (Haxthausen) Treated with Oestrone , Proc. Roy. Soc. Med. 30:738, 1937. 12. Wolf, J.: Keratoderma Climactericum , Arch. Dermat. & Syph. 43:731 ( (April) ) 1941. 13. Gans, O.: Histologie der Hautkrankheiten , Berlin, Julius Springer, 1925, vol. 1, p. 55. 14. Fox, H.: Standard Nomenclature of Disease , Arch. Dermat. & Syph. 46:534 ( (Oct.) ) 1942. 15. Becker, S. W.: Personal communication to the author. 16. Smith, M. S.: Lichen Simplex Chronicus (Neurodermatitis) of the Palms and Soles , Brit. J. Dermat. 54:255, 1942. 17. Barber, H. W.: Symmetrical Hyperkeratosis of the Palms and Soles , Brit. J. Dermat. 46:95, 1934. 18. Mierzecki: Keratoderma palmare et plantare hereditarium , Zentralbl. f. Haut- u. Geschlechtskr. 21:141, 1926. 19. Sutejec, G.: Klinik und Pathogenese der familiären symmetrischen Keratodermie , Zentralbl. f. Haut- u. Geschlechtskr. 24:798, 1927. 20. Olmsted, H. C.: Keratodermia Plantaris et Palmaris Congenitalis , Am. J. Dis. Child. 33:757 ( (May) ) 1927. 21. Henschen, C.: Ueber das Keratoderma senile volae manuum et plantae pedum und seine Heilung durch Perandren , Schweiz. med. Wchnschr. 70:690, 1940. 22. Bechet, P.: Keratosis Plantaris , Arch. Dermat. & Syph. 46:762 ( (Nov.) ) 1942. 23. MacKee, G. M., in discussion on Bechet. 24. Mussio-Fournier, J. C.: Kératodermie plantaire et palmaire chez une hypothyroïdienne , Bull. et mém. Soc. méd. d. hôp. de Paris 48:1236, 1932. 25. Niles, H. D.: A Case for Diagnosis (Keratoderma Palmare Symmetricum) , Arch. Dermat. & Syph. 34:1051 ( (Dec.) ) 1936. 26. Guy, W. H., and Jacob, F. M.: Keratoderma Plantare , Arch. Dermat. & Syph. 36:1285 ( (Dec.) ) 1937. 27. Cervino, J. M.; Bertolini, A., and Larrosa Helguera, R. A.: Keratodermias of the Hands and Feet and Thyroid Deficiency , Endocrinology 22:615, 1938. 28. Engman.6b 29. Weiss.6c

Journal

Archives of Dermatology and SyphilologyAmerican Medical Association

Published: Sep 1, 1943

References