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KERATOACANTHOMA (MOLLUSCUM SEBACEUM)

KERATOACANTHOMA (MOLLUSCUM SEBACEUM) Abstract REVIEW OF THE LITERATURE PRIOR to 1917, keratoacanthomata were regarded as cancer of the skin. Lassar1 reported three cases of epithelioma in elderly patients that were cured by oral potassium arsenite solution. One of these also received subcutaneous injections of the arsenical solution. The clinical descriptions of these patients fit keratoacanthoma. Gougert* began reporting this disease as verrucome in 1917. Subsequently case reports † were numerous in 1929. The clinicians, unable to dismiss extragenital primary syphilis from their minds even after negative dark-field and serologic examinations, "cured" several verrucomes with intravenous neoarsphenamine. Additional reports ‡ from the continent appeared with the title of verrucome or vegetating sebaceous cyst. MacCormac and Scarff8 reported 10 keratoacanthomata in 1936 as molluscum sebaceum. The salient feature of the tumor was a rapid proliferation over a four to six weeks' period. In no case was there more than References 1. Cited by Gougerot, H.; Blum, P., and Cousin.2 2. References 3 and 4. 3. References 5 to 7. 4. References 11 and 12. 5. Goodsitt, E., and Restifo, S. J.: Unpublished data. 6. Opportunity to study the pathologic changes in Fliegelman and Loveman's case was provided by Dr. Maurice Fliegelman. 7. Personal communication from Dr. Colin Wood. 8. Opportunity to study and publish this case was provided by Dr. John E. Rauschkolb. 9. This case is presented through the courtesy of the Cleveland Clinic, Department of Pathology. 10. This case is available through the courtesy of Drs. Cole, Driver, Chivington, and Sato. 11. Lassar, O.: Cancer of the Skin , Berl. klin. Wchnschr. 30:537-540, 1893 12. abstracted, Ann. dermat. et syph. 5:255, 1894. 13. Gougerot, H.; Blum, P., and Cousin: A New Case of Verrucome with Adenitis of Unknown Origin and with an Epitheliomatous Structure: Cured by Neoarsphenamine , Bull. Soc. franç. dermat. et syph. 36:255, 1929. 14. Gougerot, H.; Burnier, Eliaschoff, and Blum: Presentation of Cured Patients and of Histologic Sections of Verrucome with Adenitis and Epitheliomatous Structure: Cured by Neoarsphenamine , Bull. Soc. franç. dermat. et syph. 36:356, 1929. 15. Reference deleted. 16. Ramond, L.; Gougerot, and others: A New Case of Verrucome with Adenitis and with Epitheliomatous Structures; Cured by Neoarsphenamine , Bull. Soc. franç. dermat. et syph. 38:612, 1931. 17. Civatte, A.; Melki, G. R., and Goetschel, G. E.: Case Presentation of Verrucome , Bull. Soc. franç. dermat. et syph. 58:532, 1951. 18. Dupont, M. A.: Vegetating Sebaceous Cyst, Keratoacanthoma, Verrucome , Bull. Soc. franç. dermat. et syph. 59:340, 1952. 19. MacCormac, H., and Scarff, R. W.: Molluscum Sebaceum , Brit. J. Dermat. 48:624, 626, 1936.Crossref 20. MacCormac, H.: Molluscum Sebaceum , Proc. Roy. Soc. Med. 30:1053-1054, 1937. 21. Rook, A. J., and Whimster, I. W.: Keratoacanthoma , Arch. belges. dermat. et syph. 6:137-146, 1950. 22. Musso, L., and Gordon, H.: Spontaneous Resolution of Molluscum Sebaceum (Keratoacanthoma) , Proc. Roy. Soc. Med. 43:838, 1950. 23. Musso, L.: Spontaneous Resolution of Molluscum Sebaceum , Brit. J. Dermat. 63:151-153, 1951.Crossref 24. Whittle, C. H., and Lyell, A.: Molluscum Sebaceum (Kerotoacanthoma, Benign Epithelioma), Transactions of the Royal Society of Medicine, Section of Dermatology , Brit. J. Dermat. 64:424, 1952. 25. Beare, J. M.: Molluscum Sebaceum , in Proceedings of the 10th International Congress of Dermatology, London, 1952 , British Medical Association, 1953, pp. 476-477. 26. Hueper, W. C.: Occupational Tumors and Allied Diseases , Springfield, Ill., Charles C Thomas, Publisher, 1942, p. 165. 27. Fouracres, F. A., and Whittick, J. W.: The Relationship of Molluscum Sebaceum (Keratoacanthoma) to Spontaneously Healing Epithelioma of the Skin , Brit. J. Cancer 7:58-64, 1953.Crossref 28. Smith, J. F.: A Case of Multiple Primary Squamous Cell Carcinomata in a Young Man, with Spontaneous Healing , Brit. J. Dermat. 46:267-272, 1934.Crossref 29. Gryzbowski, M.: A Case of Peculiar Generalized Epithelial Tumors of the Skin , Brit. J. Dermat. 62:310-313, 1950.Crossref 30. Witten, V., and Zak, F. G.: Multiple Primary, Self-Healing Prickle Cell Epithelioma of the Skin , Cancer 5:539-550, 1952.Crossref 31. Sommerville, J., and Milne, J. A.: Familial Primary Self-Healing Squamous Epithelioma of Skin (Ferguson Smith Type) , Brit. J. Dermat. 62:485-490, 1950.Crossref 32. Poth, D. O.: Tumor-like Keratoses: Report of a Case , Arch. Dermat. & Syph. 39:228-238, 1939. 33. Fliegelman, M. T., and Loveman, A. B.: Tumor-like Keratoses , A. M. A. Arch. Dermat. & Syph. 66:353-357, 1952. 34. New, W. M., and Horton, S. H.: Multiple Acanthoma (Tumor-like Keratosis of Poth) in Transactions of Philadelphia Dermatological Society , A. M. A. Arch. Dermat. & Syph. 68:475-478, 1953. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

KERATOACANTHOMA (MOLLUSCUM SEBACEUM)

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References (23)

Publisher
American Medical Association
Copyright
Copyright © 1955 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1955.01540250068013
Publisher site
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Abstract

Abstract REVIEW OF THE LITERATURE PRIOR to 1917, keratoacanthomata were regarded as cancer of the skin. Lassar1 reported three cases of epithelioma in elderly patients that were cured by oral potassium arsenite solution. One of these also received subcutaneous injections of the arsenical solution. The clinical descriptions of these patients fit keratoacanthoma. Gougert* began reporting this disease as verrucome in 1917. Subsequently case reports † were numerous in 1929. The clinicians, unable to dismiss extragenital primary syphilis from their minds even after negative dark-field and serologic examinations, "cured" several verrucomes with intravenous neoarsphenamine. Additional reports ‡ from the continent appeared with the title of verrucome or vegetating sebaceous cyst. MacCormac and Scarff8 reported 10 keratoacanthomata in 1936 as molluscum sebaceum. The salient feature of the tumor was a rapid proliferation over a four to six weeks' period. In no case was there more than References 1. Cited by Gougerot, H.; Blum, P., and Cousin.2 2. References 3 and 4. 3. References 5 to 7. 4. References 11 and 12. 5. Goodsitt, E., and Restifo, S. J.: Unpublished data. 6. Opportunity to study the pathologic changes in Fliegelman and Loveman's case was provided by Dr. Maurice Fliegelman. 7. Personal communication from Dr. Colin Wood. 8. Opportunity to study and publish this case was provided by Dr. John E. Rauschkolb. 9. This case is presented through the courtesy of the Cleveland Clinic, Department of Pathology. 10. This case is available through the courtesy of Drs. Cole, Driver, Chivington, and Sato. 11. Lassar, O.: Cancer of the Skin , Berl. klin. Wchnschr. 30:537-540, 1893 12. abstracted, Ann. dermat. et syph. 5:255, 1894. 13. Gougerot, H.; Blum, P., and Cousin: A New Case of Verrucome with Adenitis of Unknown Origin and with an Epitheliomatous Structure: Cured by Neoarsphenamine , Bull. Soc. franç. dermat. et syph. 36:255, 1929. 14. Gougerot, H.; Burnier, Eliaschoff, and Blum: Presentation of Cured Patients and of Histologic Sections of Verrucome with Adenitis and Epitheliomatous Structure: Cured by Neoarsphenamine , Bull. Soc. franç. dermat. et syph. 36:356, 1929. 15. Reference deleted. 16. Ramond, L.; Gougerot, and others: A New Case of Verrucome with Adenitis and with Epitheliomatous Structures; Cured by Neoarsphenamine , Bull. Soc. franç. dermat. et syph. 38:612, 1931. 17. Civatte, A.; Melki, G. R., and Goetschel, G. E.: Case Presentation of Verrucome , Bull. Soc. franç. dermat. et syph. 58:532, 1951. 18. Dupont, M. A.: Vegetating Sebaceous Cyst, Keratoacanthoma, Verrucome , Bull. Soc. franç. dermat. et syph. 59:340, 1952. 19. MacCormac, H., and Scarff, R. W.: Molluscum Sebaceum , Brit. J. Dermat. 48:624, 626, 1936.Crossref 20. MacCormac, H.: Molluscum Sebaceum , Proc. Roy. Soc. Med. 30:1053-1054, 1937. 21. Rook, A. J., and Whimster, I. W.: Keratoacanthoma , Arch. belges. dermat. et syph. 6:137-146, 1950. 22. Musso, L., and Gordon, H.: Spontaneous Resolution of Molluscum Sebaceum (Keratoacanthoma) , Proc. Roy. Soc. Med. 43:838, 1950. 23. Musso, L.: Spontaneous Resolution of Molluscum Sebaceum , Brit. J. Dermat. 63:151-153, 1951.Crossref 24. Whittle, C. H., and Lyell, A.: Molluscum Sebaceum (Kerotoacanthoma, Benign Epithelioma), Transactions of the Royal Society of Medicine, Section of Dermatology , Brit. J. Dermat. 64:424, 1952. 25. Beare, J. M.: Molluscum Sebaceum , in Proceedings of the 10th International Congress of Dermatology, London, 1952 , British Medical Association, 1953, pp. 476-477. 26. Hueper, W. C.: Occupational Tumors and Allied Diseases , Springfield, Ill., Charles C Thomas, Publisher, 1942, p. 165. 27. Fouracres, F. A., and Whittick, J. W.: The Relationship of Molluscum Sebaceum (Keratoacanthoma) to Spontaneously Healing Epithelioma of the Skin , Brit. J. Cancer 7:58-64, 1953.Crossref 28. Smith, J. F.: A Case of Multiple Primary Squamous Cell Carcinomata in a Young Man, with Spontaneous Healing , Brit. J. Dermat. 46:267-272, 1934.Crossref 29. Gryzbowski, M.: A Case of Peculiar Generalized Epithelial Tumors of the Skin , Brit. J. Dermat. 62:310-313, 1950.Crossref 30. Witten, V., and Zak, F. G.: Multiple Primary, Self-Healing Prickle Cell Epithelioma of the Skin , Cancer 5:539-550, 1952.Crossref 31. Sommerville, J., and Milne, J. A.: Familial Primary Self-Healing Squamous Epithelioma of Skin (Ferguson Smith Type) , Brit. J. Dermat. 62:485-490, 1950.Crossref 32. Poth, D. O.: Tumor-like Keratoses: Report of a Case , Arch. Dermat. & Syph. 39:228-238, 1939. 33. Fliegelman, M. T., and Loveman, A. B.: Tumor-like Keratoses , A. M. A. Arch. Dermat. & Syph. 66:353-357, 1952. 34. New, W. M., and Horton, S. H.: Multiple Acanthoma (Tumor-like Keratosis of Poth) in Transactions of Philadelphia Dermatological Society , A. M. A. Arch. Dermat. & Syph. 68:475-478, 1953.

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A.M.A. Archives of Dermatology – American Medical Association

Published: Jan 1, 1955

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