JAMA Oncology

JAMA Oncology Editor Editor in Chief, JAMA Network Mary L. (Nora) Disis, MD Howard Bauchner, MD JAMA Oncology is committed to publishing infl uential original research, opinions, and reviews that advance the science of oncology and improve the clinical care of patients with cancer. Mission Statement JAMA Oncology is the defi nitive journal for scientists, clinicians, and trainees in the fi eld of oncology worldwide. Our original, innovative, and timely scientifi c and educational content provides a deeper understanding of cancer pathogenesis and recent treatment advances for our readers. JAMA Oncology aims to eff ectively convey the fi ndings of important clinical research, major scientifi c breakthroughs, actionable discoveries, and state-of-the-art treatment pathways to the oncology community. Our goal is that successful communication of new knowledge will ultimately translate to clinical benefi t for people living with and surviving cancer. Deputy Editors Editorial Manager Reshma Jagsi, MD, DPhil Lesley Fallowfi eld, BSc, DPhil, FMedSci Ann Arbor, Michigan East Sussex, England Lee M. Ellis, MD Kristine Pipit Houston, Texas Seattle, Washington Steven Katz, MD, MPH Heikki Joensuu, MD Telephone: (206) 543-0483 Ann Arbor, Michigan Helsinki, Finland Charles R. Thomas Jr, MD jamaonc@jamanetwork.org Portland, Oregon Michael P. Link, MD Yasufumi Kaneda, MD, PhD Editorial Assistant Palo Alto, California Osaka, Japan Associate Editor for Statistics Kate Hawkins Chadi Nabhan, MD, MBA Sibylle Loibl, MD, PhD Yu Shyr, PhD Chicago, Illinois Neu-Isenburg, Germany Nashville, Tennessee Editorial Offi ce Nathan A. Pennell, MD, PhD Dong-Young Noh, MD, PhD Center for Translational Medicine Assistant Editor for Statistics Cleveland, Ohio Seoul, South Korea in Women’s Health Fei Ye, PhD University of Washington David F. Ransohoff , MD Fred Saad, MD, FRCS Nashville, Tennessee 850 Republican St Chapel Hill, North Carolina Montreal, Quebec, Canada Associate Editor for Editorials, Box 358050 Howard Scher, MD Emile E. Voest, MD, PhD Viewpoints, and Commentaries Seattle, WA 98109-4714 New York, New York Amsterdam, The Netherlands George W. Sledge Jr, MD Telephone: (206) 543-0483 Neha Vapiwala, MD Shan Wang, MD Stanford, California jamaonc@jamanetwork.org Philadelphia, Pennsylvania Beijing, China Associate Editor for Reviews and CME EDITORIAL BOARD Robyn L. Ward, MD, PhD INTERNATIONAL ADVISORY BOARD Monica Morrow, MD Stephen M. Ansell, MD, PhD Randwick, New South Wales, Australia New York, New York Eric O. Aboagye, PhD, PharmD Rochester, Minnesota Pan-Chyr Yang, MD, PhD London, England Web Editor Taipei, Taiwan Michael J. Becich, MD, PhD Fatima Cardoso, MD Howard (Jack) West, MD Pittsburgh, Pennsylvania Lisbon, Portugal Duarte, California John C. Byrd, MD Johann S. de Bono, MB, ChB, FRCP , MSc, PhD Columbus, Ohio Surrey, England PUBLICATION STAFF Editorial Operations & Systems PERIODICAL PUBLISHING STAFF Associate Publisher/Senior Product Development Geoff rey Flick Directors Larry Bryant, Executive Editor SVP and Publisher, Periodical Publications Managers Lindsay Dawson, Ellen Gibson, Jacob Kendall-Taylor, Monica Mungle Phil B. Fontanarosa, MD, MBA Thomas J. Easley Craig McCaff rey, Michael McGraw, Managers and Staff Fanny L. Brown, Executive Managing Editor VP, Publishing Strategy & Business Daniel Pickhardt, Romando Rossini, Anna Bukowski, Lee Calibeo, Annette Flanagin Operations Sarah Subramanian, Stacy Tucker, KC Walsh Lenette Gardner-Gullens, Tosca Hall, Brian Shields Managing Editor Business Analyst Sirisha Alluri Erin Kato, Rachell Lozano, Brenda Gregoline VP, Publishing Production Operations Caroline Sietmann Staff Millette Jackson-Bates, Tom Miller, Karen Adams-Taylor Deputy Managing Editor Morgan Osgood Scientifi c Online Resources John McFadden VP, Digital Product Management and Deputy Editor and Director Business Operations Michael Berkwits, MD Development Paul Gee Manuscript Editors Directors Karl Elvin, Nancy Essex, Cheryl T. Davidow, Gabriel Dietz, Staff Monica Smith Jaye Mize, Sean O’Donnell, Sue Sherrill Digital Media Production Amy Nicoletti, Jamie Scott Eric Butkus, Jesse McQuarters (managers); Managers David Antos, Anthony Bautista, Advertising Sales and Marketing Freelance Manuscript Editing Manager Elena Guobyte, Emily Ling, Daniel Morrow Chris Borden, Debbie Camp, Jennifer Director Jeff ery J. Bonistalli Connie L. Manno (producers) Carney, Lydia Cruz, Scott Curl, Diane Darnell, Manager Kathy Russell Nanette Diaz, Jordynn Farrar, Allison Social Media Eman Hassaballa Aly Senior Freelance Manuscript Editing Staff Mirna Monal Hughes, Tiff any Jones, Colleen Kelly, John (manager); Reuben Rios (coordinator) Coordinator Lash, Chris Meyer, Annemarie Neff , J.D. Sara M. Billings Sales Representatives Electronic Media Systems and Services Neff , Sean Ohlson, Phil O’Leary, Bill Pedone, Maureen A. Reichert, Nancy E. Souza Mary Lynn Ferkaluk Freelance Manuscript Editing Susan Price, Jaynam Shah, Erin Spencer, Director, Marketing Mark Thornbury Coordinators Editorial Graphics Denise Steinhauser, Joe Wixted Timothy Gray, Juliet A. Orellana, Paul Ruich, Staff Tricia Castellano Staff Karen Bucher, Andy Rekito, Advertising and Production Services Kirby Snell Recruitment Advertising Nick Reback, Lohitha Kethu, David Song Ahmed Avendano, Kim Boler, Freelance Copy Editors and Copyreaders Director Anna Frazier Rhonda Bailey Brown, Fin Carter, Clinical Review and Education Catherine A. Alden, Michael Deegan, Daniel DeGroot, Manager Thalia Moss Deputy Editor Edward H. Livingston, MD Stephanie Lang Beckmeyer, Jane Calayag, Euwanaha Joiner-Smith, Joshua Lane, Staff Sade DeRamus-Townsend, CME Editor Thomas B. Cole, MD, MPH Jan Clavey, Mary Coerver-Connolly, Cindy Rendlen, Ellen Yoshihara Tony Ralenkotter Paula Glitman, Laura King, Budgets and Administration Circulation Services Julie Burton, Reprint Sales Divya Screekumar, Regina Z. Lilly, Charon Director Marla A. Hall Ronna Hewitt, Mary Sieck, Pierson, Rebecca J. Ritke, Thressa D. Smith, Sales Representatives Marsha Fogler, Geneine Van Someren, Jamaal Vargas Staff Deanna Willis, Yolanda Davis Donna J. Thordsen, Christine Tilles, Rachel Sisholtz Content Production Systems Caroline A. V. Woods Editorial Counsel Circulation Sales and Marketing Mike Bujewski, Nathan Mitre Joseph P. Thornton, JD Editorial Assistant Director, Worldwide Sales Digital Production Media Relations Wanda Hill Vida Damijonaitis Regina Brownlee, Amanda Camino, Manager Deanna Bellandi Managers Saskia Bolore, Brenda Chandler-Grayer, Emily Dunn, Staff Jim Michalski Gretchen Linder, Brian McCartney Amy Evers, Maleeka Holden, Teri Hutchison, Dan Knowles, Joshua Lampinen, Sales Representatives Natalie Marsh, Patricia E. Panek, Marla Seidell, Christine Hearne, Natasha Nekola La’son Diggs Sledge, Julian Wiley Staff Henry Aguillar, David Baum, Graphics Joe Amft, James Collver, Ron Thomas Maria Duda, Fred Furtner, Carolyn Hall, Marketing and Product Development Maria Kowalkowski Directors Rick Bell, Elizabeth Solaro, Proofreading Carol Joy Farrell, Sara Zimmerman Maria Giannini, Sasha Grossman, Judith A. Literskis, Teresa H. Omiotek, Michael Ryder JAMA Network is a consortium of peer-reviewed medical publications that includes JAMA® and the AMA EXECUTIVES JAMA Network journals. JAMA Oncology does not hold itself responsible for statements made by any Executive Vice President, contributor. All articles published, including opinion articles, represent the views of the authors and do Chief Executive Offi cer not refl ect the policy of the Journal, the American Medical Association, or the institution with which James L. Madara, MD the author is affi liated, unless otherwise indicated. © 2020 American Medical Association. All rights reserved. Reproduction without permission is prohibited. jamaoncology.com JAMA Oncology February 2020 Volume 6, Number 2 173 Copyright 2020 American Medical Association. All rights reserved. Copyright 2020 American Medical Association. All rights reserved. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Oncology American Medical Association

JAMA Oncology

JAMA Oncology, Volume 6 (2) – Feb 1, 2020

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Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
2374-2437
eISSN
2374-2445
DOI
10.1001/jamaoncol.2019.4203
Publisher site
See Article on Publisher Site

Abstract

Editor Editor in Chief, JAMA Network Mary L. (Nora) Disis, MD Howard Bauchner, MD JAMA Oncology is committed to publishing infl uential original research, opinions, and reviews that advance the science of oncology and improve the clinical care of patients with cancer. Mission Statement JAMA Oncology is the defi nitive journal for scientists, clinicians, and trainees in the fi eld of oncology worldwide. Our original, innovative, and timely scientifi c and educational content provides a deeper understanding of cancer pathogenesis and recent treatment advances for our readers. JAMA Oncology aims to eff ectively convey the fi ndings of important clinical research, major scientifi c breakthroughs, actionable discoveries, and state-of-the-art treatment pathways to the oncology community. Our goal is that successful communication of new knowledge will ultimately translate to clinical benefi t for people living with and surviving cancer. Deputy Editors Editorial Manager Reshma Jagsi, MD, DPhil Lesley Fallowfi eld, BSc, DPhil, FMedSci Ann Arbor, Michigan East Sussex, England Lee M. Ellis, MD Kristine Pipit Houston, Texas Seattle, Washington Steven Katz, MD, MPH Heikki Joensuu, MD Telephone: (206) 543-0483 Ann Arbor, Michigan Helsinki, Finland Charles R. Thomas Jr, MD jamaonc@jamanetwork.org Portland, Oregon Michael P. Link, MD Yasufumi Kaneda, MD, PhD Editorial Assistant Palo Alto, California Osaka, Japan Associate Editor for Statistics Kate Hawkins Chadi Nabhan, MD, MBA Sibylle Loibl, MD, PhD Yu Shyr, PhD Chicago, Illinois Neu-Isenburg, Germany Nashville, Tennessee Editorial Offi ce Nathan A. Pennell, MD, PhD Dong-Young Noh, MD, PhD Center for Translational Medicine Assistant Editor for Statistics Cleveland, Ohio Seoul, South Korea in Women’s Health Fei Ye, PhD University of Washington David F. Ransohoff , MD Fred Saad, MD, FRCS Nashville, Tennessee 850 Republican St Chapel Hill, North Carolina Montreal, Quebec, Canada Associate Editor for Editorials, Box 358050 Howard Scher, MD Emile E. Voest, MD, PhD Viewpoints, and Commentaries Seattle, WA 98109-4714 New York, New York Amsterdam, The Netherlands George W. Sledge Jr, MD Telephone: (206) 543-0483 Neha Vapiwala, MD Shan Wang, MD Stanford, California jamaonc@jamanetwork.org Philadelphia, Pennsylvania Beijing, China Associate Editor for Reviews and CME EDITORIAL BOARD Robyn L. Ward, MD, PhD INTERNATIONAL ADVISORY BOARD Monica Morrow, MD Stephen M. Ansell, MD, PhD Randwick, New South Wales, Australia New York, New York Eric O. Aboagye, PhD, PharmD Rochester, Minnesota Pan-Chyr Yang, MD, PhD London, England Web Editor Taipei, Taiwan Michael J. Becich, MD, PhD Fatima Cardoso, MD Howard (Jack) West, MD Pittsburgh, Pennsylvania Lisbon, Portugal Duarte, California John C. Byrd, MD Johann S. de Bono, MB, ChB, FRCP , MSc, PhD Columbus, Ohio Surrey, England PUBLICATION STAFF Editorial Operations & Systems PERIODICAL PUBLISHING STAFF Associate Publisher/Senior Product Development Geoff rey Flick Directors Larry Bryant, Executive Editor SVP and Publisher, Periodical Publications Managers Lindsay Dawson, Ellen Gibson, Jacob Kendall-Taylor, Monica Mungle Phil B. Fontanarosa, MD, MBA Thomas J. Easley Craig McCaff rey, Michael McGraw, Managers and Staff Fanny L. Brown, Executive Managing Editor VP, Publishing Strategy & Business Daniel Pickhardt, Romando Rossini, Anna Bukowski, Lee Calibeo, Annette Flanagin Operations Sarah Subramanian, Stacy Tucker, KC Walsh Lenette Gardner-Gullens, Tosca Hall, Brian Shields Managing Editor Business Analyst Sirisha Alluri Erin Kato, Rachell Lozano, Brenda Gregoline VP, Publishing Production Operations Caroline Sietmann Staff Millette Jackson-Bates, Tom Miller, Karen Adams-Taylor Deputy Managing Editor Morgan Osgood Scientifi c Online Resources John McFadden VP, Digital Product Management and Deputy Editor and Director Business Operations Michael Berkwits, MD Development Paul Gee Manuscript Editors Directors Karl Elvin, Nancy Essex, Cheryl T. Davidow, Gabriel Dietz, Staff Monica Smith Jaye Mize, Sean O’Donnell, Sue Sherrill Digital Media Production Amy Nicoletti, Jamie Scott Eric Butkus, Jesse McQuarters (managers); Managers David Antos, Anthony Bautista, Advertising Sales and Marketing Freelance Manuscript Editing Manager Elena Guobyte, Emily Ling, Daniel Morrow Chris Borden, Debbie Camp, Jennifer Director Jeff ery J. Bonistalli Connie L. Manno (producers) Carney, Lydia Cruz, Scott Curl, Diane Darnell, Manager Kathy Russell Nanette Diaz, Jordynn Farrar, Allison Social Media Eman Hassaballa Aly Senior Freelance Manuscript Editing Staff Mirna Monal Hughes, Tiff any Jones, Colleen Kelly, John (manager); Reuben Rios (coordinator) Coordinator Lash, Chris Meyer, Annemarie Neff , J.D. Sara M. Billings Sales Representatives Electronic Media Systems and Services Neff , Sean Ohlson, Phil O’Leary, Bill Pedone, Maureen A. Reichert, Nancy E. Souza Mary Lynn Ferkaluk Freelance Manuscript Editing Susan Price, Jaynam Shah, Erin Spencer, Director, Marketing Mark Thornbury Coordinators Editorial Graphics Denise Steinhauser, Joe Wixted Timothy Gray, Juliet A. Orellana, Paul Ruich, Staff Tricia Castellano Staff Karen Bucher, Andy Rekito, Advertising and Production Services Kirby Snell Recruitment Advertising Nick Reback, Lohitha Kethu, David Song Ahmed Avendano, Kim Boler, Freelance Copy Editors and Copyreaders Director Anna Frazier Rhonda Bailey Brown, Fin Carter, Clinical Review and Education Catherine A. Alden, Michael Deegan, Daniel DeGroot, Manager Thalia Moss Deputy Editor Edward H. Livingston, MD Stephanie Lang Beckmeyer, Jane Calayag, Euwanaha Joiner-Smith, Joshua Lane, Staff Sade DeRamus-Townsend, CME Editor Thomas B. Cole, MD, MPH Jan Clavey, Mary Coerver-Connolly, Cindy Rendlen, Ellen Yoshihara Tony Ralenkotter Paula Glitman, Laura King, Budgets and Administration Circulation Services Julie Burton, Reprint Sales Divya Screekumar, Regina Z. Lilly, Charon Director Marla A. Hall Ronna Hewitt, Mary Sieck, Pierson, Rebecca J. Ritke, Thressa D. Smith, Sales Representatives Marsha Fogler, Geneine Van Someren, Jamaal Vargas Staff Deanna Willis, Yolanda Davis Donna J. Thordsen, Christine Tilles, Rachel Sisholtz Content Production Systems Caroline A. V. Woods Editorial Counsel Circulation Sales and Marketing Mike Bujewski, Nathan Mitre Joseph P. Thornton, JD Editorial Assistant Director, Worldwide Sales Digital Production Media Relations Wanda Hill Vida Damijonaitis Regina Brownlee, Amanda Camino, Manager Deanna Bellandi Managers Saskia Bolore, Brenda Chandler-Grayer, Emily Dunn, Staff Jim Michalski Gretchen Linder, Brian McCartney Amy Evers, Maleeka Holden, Teri Hutchison, Dan Knowles, Joshua Lampinen, Sales Representatives Natalie Marsh, Patricia E. Panek, Marla Seidell, Christine Hearne, Natasha Nekola La’son Diggs Sledge, Julian Wiley Staff Henry Aguillar, David Baum, Graphics Joe Amft, James Collver, Ron Thomas Maria Duda, Fred Furtner, Carolyn Hall, Marketing and Product Development Maria Kowalkowski Directors Rick Bell, Elizabeth Solaro, Proofreading Carol Joy Farrell, Sara Zimmerman Maria Giannini, Sasha Grossman, Judith A. Literskis, Teresa H. Omiotek, Michael Ryder JAMA Network is a consortium of peer-reviewed medical publications that includes JAMA® and the AMA EXECUTIVES JAMA Network journals. JAMA Oncology does not hold itself responsible for statements made by any Executive Vice President, contributor. All articles published, including opinion articles, represent the views of the authors and do Chief Executive Offi cer not refl ect the policy of the Journal, the American Medical Association, or the institution with which James L. Madara, MD the author is affi liated, unless otherwise indicated. © 2020 American Medical Association. All rights reserved. Reproduction without permission is prohibited. jamaoncology.com JAMA Oncology February 2020 Volume 6, Number 2 173 Copyright 2020 American Medical Association. All rights reserved. Copyright 2020 American Medical Association. All rights reserved.

Journal

JAMA OncologyAmerican Medical Association

Published: Feb 1, 2020

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