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JAMA Oncology

JAMA Oncology JAMA Oncology is committed to publishing influential original research, opinions, and reviews that advance the science of oncology and improve the clinical care of patients with cancer. Mission Statement: JAMA Oncology is the definitive journal for scientists, clinicians, and trainees in the field of oncology worldwide. Our original, innovative, and timely scientific and educational content provides a deeper understanding of cancer pathogenesis and recent treatment advances for our readers. JAMA Oncology aims to effectively convey the findings of important clinical research, major scientific breakthroughs, actionable discoveries, and state-of-the-art treatment pathways to the oncology community. Our goal is that successful communication of new knowledge will ultimately translate to clinical benefit for people living with and surviving cancer. Editor Mary L. (Nora) Disis, MD, Seattle, Washington Deputy Editors Lee M. Ellis, MD, Houston, Texas Charles R. Thomas Jr, MD, Portland, Oregon Associate Editor for Statistics Yu Shyr, PhD, Nashville, Tennessee Associate Editor for Editorials, Viewpoints, and Commentaries George W. Sledge Jr, MD, Stanford, California Associate Editor for Reviews and CME Monica Morrow, MD, New York, New York Web Editor Howard (Jack) West, MD, Seattle, Washington Editorial Manager Kim Agricola, Seattle, Washington Telephone: (206) 543-0483 jamaonc@jamanetwork.org Editorial Office Center for Translational Medicine in Women’s Health University of Washington 850 Republican St, Box 358050 Seattle, WA 98109-4714 Editorial Board Leslie Bernstein, PhD, Duarte, California Tito Fojo, MD, PhD, Bethesda, Maryland Charles Fuchs, MD, MPH, Boston, Massachusetts Reshma Jagsi, MD, DPhil, Ann Arbor, Michigan Rakesh Jain, PhD, Boston, Massachusetts David H. Johnson, MD, Dallas, Texas Steven Katz, MD, MPH, Ann Arbor, Michigan Edison Liu, MD, Bar Harbor, Maine Minesh Mehta, MBChB, Baltimore, Maryland Chadi Nabhan, MD, Chicago, Illinois Steven Narod, MD, Toronto, Ontario Howard Scher, MD, New York, New York Larry Schwartz, MD, New York, New York David Sidransky, MD, Baltimore, Maryland Lillian Siu, MD, FRCPC, Toronto, Ontario International Advisory Board Eric O. Aboagye, PhD, PharmD, London, England Fatima Cardoso, MD, Lisbon, Portugal Johann S. de Bono, MB, ChB, FRCP, MSc, PhD, Surrey, England Lesley Fallowfield, BSc, DPhil, FMedSci, East Sussex, England Heikki Joensuu, MD, Helsinki, Finland Yasufumi Kaneda, MD, PhD, Osaka, Japan Sibylle Loibl, MD, PhD, Neu-Isenburg, Germany Dong-Young Noh, MD, PhD, Seoul, South Korea Fred Saad, MD, FRCS, Montreal, Quebec, Canada Emile E. Voest, MD, PhD, Amsterdam, The Netherlands Shan Wang, MD, Beijing, China Robyn L. Ward, MD, PhD, Randwick, New South Wales, Australia Pan-Chyr Yang, MD, PhD, Taipei, Taiwan Publication Staff Offices 330 N Wabash Ave, Chicago, IL 60611 Editor in Chief, The JAMA Network Howard Bauchner, MD Executive Editor Phil B. Fontanarosa, MD, MBA Executive Managing Editor Annette Flanagin Managing Editor Brenda Gregoline Editorial Processing Manuscript Editing Manager Lauren Fischer Senior Manuscript Editor John McFadden Manuscript Editors Karen L. Boyd, Gabriel Dietz, Rochelle C. Lodder, Sam Wilder Freelance Manuscript Editing Manager Diane L. Cannon Freelance Manuscript Editing Coordinators Connie L. Manno, Fred Marshall Freelance Copy Editors and Copyreaders Catherine A. Alden, Stephanie Lang Beckmeyer, Jan Clavey, Mary Coerver-Connolly, Paula Glitman, Laura King, Kenneth W. Lane, Donna J. Thordsen, Caroline Woods Editorial Assistant Wanda Hill Editorial Operations and Systems Directors Larry Bryant, Monica Mungle, Elaine Williams Managers and Staff Kathryn Brokke, Fanny L. Brown, Paul Frank, Lenette Gardner-Gullens, Peter K. Kim, Rachell Lozano, Michaela Mark, Elizabeth Zak Scientific Online Resources Deputy Editor and Director Michael Berkwits, MD Director, Development and Design Michelle Kurzynski Staff Eric Butkus, Will English IV, Mustafa Ishaq, Daniel Morrow, Reuben Rios Editorial Graphics Deputy Editor and Director Ronna Henry, MD Staff Joshua Bird, Karen Bucher, Samantha Welker, David Song Clinical Review & Education Deputy Editor Edward H. Livingston, MD CME Editor Thomas B. Cole, MD, MPH Administration Director Marla A. Hall Staff Deanna Willis, Yolanda Davis Editorial Counsel Joseph P. Thornton, JD Media Relations Staff Preeti Malani, MD, MSJ, Deanna Bellandi, Jim Michalski Periodical Publishing Staff Senior Vice President and Publisher, Periodical Publications Thomas J. Easley Vice President, Publishing Business Operations Brian Shields Staff Monica Smith Advertising Print & Online Sales & Marketing Director Jeffery J. Bonistalli Manager Kathy Russell Staff Mirna Monal Sales Representatives Maureen A. Reichert, Nancy E. Souza Director, Marketing Mark Thornbury Staff Tricia Castellano Classified Advertising Manager Thalia Moss Staff Mike Harvey,Susan J. Henning Reprint Communications Manager Susan Lovenberg Circulation Print & Online Sales & Marketing Director, Worldwide Sales Vida Damijonaitis Managers Saskia Bolore, Gretchen Linder, Brian McCartney Staff David Baum,Rebecca Haas, Christine Hearne, Natasha Nekola, Ron Thomas Marketing and Product Development Directors Paul Gee,Matt Herron, Elizabeth Solaro Associate Publisher/Senior Product Development Geoffrey Flick Managers Rick Bell, Lindsay Dawson, Craig McCaffrey, Michael McGraw, Romando Rossini, Stacy Tucker Staff Millette Jackson-Bates Business Operations Directors Karen Adams-Taylor, Karl Elvin, Jaye Mize, Sean O’Donnell, Sue Sherrill Managers David Antos, Chris Borden, Debbie Camp, Lydia Cruz, Scott Curl, Diane Darnell, Colleen Kelly, Chris Meyer, Annemarie Neff, J.D. Neff, Sean Ohlson, Phil O'Leary, Bill Pedone, Susan Price, Denise Steinhauser, Joe Wixted Advertising and Production Services Kim Boler, Rhonda Bailey Brown, Daniel DeGroot, Jordynn Farrar, Euwanaha Joiner-Smith, Tiffany Jones, Cindy Rendlen, Ellen Yoshihara Circulation Services Julie Burton, Dexter Golden, Erin Hinchcliff, Noemi Rivera, Geneine Van Someren Composition and New Media Gail Barrett, Regina Brownlee, Amanda Camino, Brenda Chandler-Grayer, Emily Dunn, Amy Evers, Teri Hutchison, Mary Ann Kuranda, Joshua Lampinen, Nathan Mitre, Patricia E. Panek, La'son Diggs Sledge, George Thomson Graphics Joe Amft, Maria Duda, Fred Furtner, Carolyn Hall, Maria Kowalkowski Proofreading Carol Joy Farrell, Daniel James, Judith A. Literskis, Teresa H. Omiotek, Michael Ryder AMA Executives Executive Vice President, Chief Executive Officer James L. Madara, MD Chief Operating Officer Bernard L. Hengesbaugh The JAMA Network is a consortium of peer-reviewed print and online medical publications that includes JAMA®, JAMA Oncology and other specialty journals. All articles published, including editorials, letters, and book reviews, represent the opinions of the authors and do not reflect the policy of the American Medical Association, the Editorial Board, or the institution with which the author is affiliated, unless this is clearly specified. © 2015 American Medical Association. All rights reserved. Reproduction without permission is prohibited. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Oncology American Medical Association

JAMA Oncology

JAMA Oncology , Volume 1 (9) – Dec 1, 2015

JAMA Oncology

Abstract

JAMA Oncology is committed to publishing influential original research, opinions, and reviews that advance the science of oncology and improve the clinical care of patients with cancer. Mission Statement: JAMA Oncology is the definitive journal for scientists, clinicians, and trainees in the field of oncology worldwide. Our original, innovative, and timely scientific and educational content provides a deeper understanding of cancer pathogenesis and recent treatment advances for our readers....
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Publisher
American Medical Association
Copyright
Copyright © 2015 American Medical Association. All Rights Reserved.
ISSN
2374-2437
eISSN
2374-2445
DOI
10.1001/jamaoncol.2014.252
Publisher site
See Article on Publisher Site

Abstract

JAMA Oncology is committed to publishing influential original research, opinions, and reviews that advance the science of oncology and improve the clinical care of patients with cancer. Mission Statement: JAMA Oncology is the definitive journal for scientists, clinicians, and trainees in the field of oncology worldwide. Our original, innovative, and timely scientific and educational content provides a deeper understanding of cancer pathogenesis and recent treatment advances for our readers. JAMA Oncology aims to effectively convey the findings of important clinical research, major scientific breakthroughs, actionable discoveries, and state-of-the-art treatment pathways to the oncology community. Our goal is that successful communication of new knowledge will ultimately translate to clinical benefit for people living with and surviving cancer. Editor Mary L. (Nora) Disis, MD, Seattle, Washington Deputy Editors Lee M. Ellis, MD, Houston, Texas Charles R. Thomas Jr, MD, Portland, Oregon Associate Editor for Statistics Yu Shyr, PhD, Nashville, Tennessee Associate Editor for Editorials, Viewpoints, and Commentaries George W. Sledge Jr, MD, Stanford, California Associate Editor for Reviews and CME Monica Morrow, MD, New York, New York Web Editor Howard (Jack) West, MD, Seattle, Washington Editorial Manager Kim Agricola, Seattle, Washington Telephone: (206) 543-0483 jamaonc@jamanetwork.org Editorial Office Center for Translational Medicine in Women’s Health University of Washington 850 Republican St, Box 358050 Seattle, WA 98109-4714 Editorial Board Leslie Bernstein, PhD, Duarte, California Tito Fojo, MD, PhD, Bethesda, Maryland Charles Fuchs, MD, MPH, Boston, Massachusetts Reshma Jagsi, MD, DPhil, Ann Arbor, Michigan Rakesh Jain, PhD, Boston, Massachusetts David H. Johnson, MD, Dallas, Texas Steven Katz, MD, MPH, Ann Arbor, Michigan Edison Liu, MD, Bar Harbor, Maine Minesh Mehta, MBChB, Baltimore, Maryland Chadi Nabhan, MD, Chicago, Illinois Steven Narod, MD, Toronto, Ontario Howard Scher, MD, New York, New York Larry Schwartz, MD, New York, New York David Sidransky, MD, Baltimore, Maryland Lillian Siu, MD, FRCPC, Toronto, Ontario International Advisory Board Eric O. Aboagye, PhD, PharmD, London, England Fatima Cardoso, MD, Lisbon, Portugal Johann S. de Bono, MB, ChB, FRCP, MSc, PhD, Surrey, England Lesley Fallowfield, BSc, DPhil, FMedSci, East Sussex, England Heikki Joensuu, MD, Helsinki, Finland Yasufumi Kaneda, MD, PhD, Osaka, Japan Sibylle Loibl, MD, PhD, Neu-Isenburg, Germany Dong-Young Noh, MD, PhD, Seoul, South Korea Fred Saad, MD, FRCS, Montreal, Quebec, Canada Emile E. Voest, MD, PhD, Amsterdam, The Netherlands Shan Wang, MD, Beijing, China Robyn L. Ward, MD, PhD, Randwick, New South Wales, Australia Pan-Chyr Yang, MD, PhD, Taipei, Taiwan Publication Staff Offices 330 N Wabash Ave, Chicago, IL 60611 Editor in Chief, The JAMA Network Howard Bauchner, MD Executive Editor Phil B. Fontanarosa, MD, MBA Executive Managing Editor Annette Flanagin Managing Editor Brenda Gregoline Editorial Processing Manuscript Editing Manager Lauren Fischer Senior Manuscript Editor John McFadden Manuscript Editors Karen L. Boyd, Gabriel Dietz, Rochelle C. Lodder, Sam Wilder Freelance Manuscript Editing Manager Diane L. Cannon Freelance Manuscript Editing Coordinators Connie L. Manno, Fred Marshall Freelance Copy Editors and Copyreaders Catherine A. Alden, Stephanie Lang Beckmeyer, Jan Clavey, Mary Coerver-Connolly, Paula Glitman, Laura King, Kenneth W. Lane, Donna J. Thordsen, Caroline Woods Editorial Assistant Wanda Hill Editorial Operations and Systems Directors Larry Bryant, Monica Mungle, Elaine Williams Managers and Staff Kathryn Brokke, Fanny L. Brown, Paul Frank, Lenette Gardner-Gullens, Peter K. Kim, Rachell Lozano, Michaela Mark, Elizabeth Zak Scientific Online Resources Deputy Editor and Director Michael Berkwits, MD Director, Development and Design Michelle Kurzynski Staff Eric Butkus, Will English IV, Mustafa Ishaq, Daniel Morrow, Reuben Rios Editorial Graphics Deputy Editor and Director Ronna Henry, MD Staff Joshua Bird, Karen Bucher, Samantha Welker, David Song Clinical Review & Education Deputy Editor Edward H. Livingston, MD CME Editor Thomas B. Cole, MD, MPH Administration Director Marla A. Hall Staff Deanna Willis, Yolanda Davis Editorial Counsel Joseph P. Thornton, JD Media Relations Staff Preeti Malani, MD, MSJ, Deanna Bellandi, Jim Michalski Periodical Publishing Staff Senior Vice President and Publisher, Periodical Publications Thomas J. Easley Vice President, Publishing Business Operations Brian Shields Staff Monica Smith Advertising Print & Online Sales & Marketing Director Jeffery J. Bonistalli Manager Kathy Russell Staff Mirna Monal Sales Representatives Maureen A. Reichert, Nancy E. Souza Director, Marketing Mark Thornbury Staff Tricia Castellano Classified Advertising Manager Thalia Moss Staff Mike Harvey,Susan J. Henning Reprint Communications Manager Susan Lovenberg Circulation Print & Online Sales & Marketing Director, Worldwide Sales Vida Damijonaitis Managers Saskia Bolore, Gretchen Linder, Brian McCartney Staff David Baum,Rebecca Haas, Christine Hearne, Natasha Nekola, Ron Thomas Marketing and Product Development Directors Paul Gee,Matt Herron, Elizabeth Solaro Associate Publisher/Senior Product Development Geoffrey Flick Managers Rick Bell, Lindsay Dawson, Craig McCaffrey, Michael McGraw, Romando Rossini, Stacy Tucker Staff Millette Jackson-Bates Business Operations Directors Karen Adams-Taylor, Karl Elvin, Jaye Mize, Sean O’Donnell, Sue Sherrill Managers David Antos, Chris Borden, Debbie Camp, Lydia Cruz, Scott Curl, Diane Darnell, Colleen Kelly, Chris Meyer, Annemarie Neff, J.D. Neff, Sean Ohlson, Phil O'Leary, Bill Pedone, Susan Price, Denise Steinhauser, Joe Wixted Advertising and Production Services Kim Boler, Rhonda Bailey Brown, Daniel DeGroot, Jordynn Farrar, Euwanaha Joiner-Smith, Tiffany Jones, Cindy Rendlen, Ellen Yoshihara Circulation Services Julie Burton, Dexter Golden, Erin Hinchcliff, Noemi Rivera, Geneine Van Someren Composition and New Media Gail Barrett, Regina Brownlee, Amanda Camino, Brenda Chandler-Grayer, Emily Dunn, Amy Evers, Teri Hutchison, Mary Ann Kuranda, Joshua Lampinen, Nathan Mitre, Patricia E. Panek, La'son Diggs Sledge, George Thomson Graphics Joe Amft, Maria Duda, Fred Furtner, Carolyn Hall, Maria Kowalkowski Proofreading Carol Joy Farrell, Daniel James, Judith A. Literskis, Teresa H. Omiotek, Michael Ryder AMA Executives Executive Vice President, Chief Executive Officer James L. Madara, MD Chief Operating Officer Bernard L. Hengesbaugh The JAMA Network is a consortium of peer-reviewed print and online medical publications that includes JAMA®, JAMA Oncology and other specialty journals. All articles published, including editorials, letters, and book reviews, represent the opinions of the authors and do not reflect the policy of the American Medical Association, the Editorial Board, or the institution with which the author is affiliated, unless this is clearly specified. © 2015 American Medical Association. All rights reserved. Reproduction without permission is prohibited.

Journal

JAMA OncologyAmerican Medical Association

Published: Dec 1, 2015

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