Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Isolated Pupil-Sparing Third-Nerve Palsy as the Presenting Sign of Multiple Sclerosis

Isolated Pupil-Sparing Third-Nerve Palsy as the Presenting Sign of Multiple Sclerosis Abstract • A 27-year-old man presented with an isolated, pupil-sparing, partial third-nerve palsy. Etiologic investigations proved unrevealing. Subsequent development of an optic neuropathy prompted magnetic resonance imaging, which confirmed the clinical suspicion of multiple sclerosis. Rarely does multiple sclerosis present with oculomotor nerve involvement. References 1. Rucker CW. Paralysis of the third, fourth and sixth cranial nerves . Am J Ophthalmol . 1958;46:787-794. 2. Goldstein JE, Cogan DG. Diabetic ophthalmoplegia with special reference to the pupil . Arch Ophthalmol . 1960;64:592-600.Crossref 3. Green WR, Hackett ER, Schlezinger NS. Neuro-ophthalmologic evaluation of oculomotor nerve paralysis . Arch ophthalmol . 1964;72:154-167.Crossref 4. Rucker CW. The causes of paralysis of the third, fourth and sixth cranial nerves . Am J Ophthalmol . 1966;61:1293-1298. 5. Rush JA, Younge BR. Paralysis of cranial nerves III, IV, and VI: cause and prognosis in 1000 cases . Arch Ophthalmol . 1981;99:76-79.Crossref 6. McAlpine D, Compston ND, Lumsden CE. Early symptomatology—continued . In: Multiple Sclerosis . Edinburgh, Scotland: E & S Livingstone; 1955:94.96. 7. Walsh FB, Hoyt WF. Heredofamilial and degenerative diseases . In: Clinical Neuroophthalmology . 3rd ed. Baltimore, Md: Williams & Wilkins; 1969:985-986. 8. Matthews WB, Acheson ED, Batchelor JR, Weller RO. Symptoms and signs (contd) . In: McAlpine's Multiple Sclerosis . New York, NY: Churchill Livingstone Inc; 1985:130-131. 9. Nadeau SE, Trobe JD. Pupil sparing in oculomotor palsy: a brief review . Ann Neurol . 1983;13:143-148.Crossref 10. Breen LA, Farris BK, Gutmann L, Hopf HC. Pupil-sparing oculomotor nerve palsy due to a midbrain infarct . Neurology . 1989;39( (suppl 1) ):355.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Isolated Pupil-Sparing Third-Nerve Palsy as the Presenting Sign of Multiple Sclerosis

Archives of Neurology , Volume 47 (7) – Jul 1, 1990

Loading next page...
 
/lp/american-medical-association/isolated-pupil-sparing-third-nerve-palsy-as-the-presenting-sign-of-VqW9j6Z4Jy
Publisher
American Medical Association
Copyright
Copyright © 1990 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1990.00530070117021
Publisher site
See Article on Publisher Site

Abstract

Abstract • A 27-year-old man presented with an isolated, pupil-sparing, partial third-nerve palsy. Etiologic investigations proved unrevealing. Subsequent development of an optic neuropathy prompted magnetic resonance imaging, which confirmed the clinical suspicion of multiple sclerosis. Rarely does multiple sclerosis present with oculomotor nerve involvement. References 1. Rucker CW. Paralysis of the third, fourth and sixth cranial nerves . Am J Ophthalmol . 1958;46:787-794. 2. Goldstein JE, Cogan DG. Diabetic ophthalmoplegia with special reference to the pupil . Arch Ophthalmol . 1960;64:592-600.Crossref 3. Green WR, Hackett ER, Schlezinger NS. Neuro-ophthalmologic evaluation of oculomotor nerve paralysis . Arch ophthalmol . 1964;72:154-167.Crossref 4. Rucker CW. The causes of paralysis of the third, fourth and sixth cranial nerves . Am J Ophthalmol . 1966;61:1293-1298. 5. Rush JA, Younge BR. Paralysis of cranial nerves III, IV, and VI: cause and prognosis in 1000 cases . Arch Ophthalmol . 1981;99:76-79.Crossref 6. McAlpine D, Compston ND, Lumsden CE. Early symptomatology—continued . In: Multiple Sclerosis . Edinburgh, Scotland: E & S Livingstone; 1955:94.96. 7. Walsh FB, Hoyt WF. Heredofamilial and degenerative diseases . In: Clinical Neuroophthalmology . 3rd ed. Baltimore, Md: Williams & Wilkins; 1969:985-986. 8. Matthews WB, Acheson ED, Batchelor JR, Weller RO. Symptoms and signs (contd) . In: McAlpine's Multiple Sclerosis . New York, NY: Churchill Livingstone Inc; 1985:130-131. 9. Nadeau SE, Trobe JD. Pupil sparing in oculomotor palsy: a brief review . Ann Neurol . 1983;13:143-148.Crossref 10. Breen LA, Farris BK, Gutmann L, Hopf HC. Pupil-sparing oculomotor nerve palsy due to a midbrain infarct . Neurology . 1989;39( (suppl 1) ):355.Crossref

Journal

Archives of NeurologyAmerican Medical Association

Published: Jul 1, 1990

References