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Is the Risk of Incidence or Progression of Age-Related Macular Degeneration Increased After Cataract Surgery?

Is the Risk of Incidence or Progression of Age-Related Macular Degeneration Increased After... EDITORIAL Is the Risk of Incidence or Progression of Age-Related Macular Degeneration Increased After Cataract Surgery? INCE THE LATE 1980S, THERE HAVE BEEN tween cataract surgery and early or late AMD. Prevalence several reports of an association between cata- analyses from the Rotterdam Study showed no increased ract surgery and age-related macular degen- risk of wet or dry AMD in pseudophakic eyes but did re- 1-11 17 eration (AMD). Some report a cross- port increased risk of early AMD. 1,2,8 S sectional association ; some, incidence of Five-yearincidenceanalysesofpooleddatafromtheBea- 9,10 AMD after surgery ; and yet others report progression ver Dam Eye Study and the Blue Mountains Eye Study (any 4,5,10 to more severe AMD. Still, there are some studies that late AMD, odds ratio [OR], 5.7; 95% confidence interval do not find a significant association after controlling for [CI], 2.4-13.6) and the Rotterdam Study (only dry AMD, 12,13 17 relevant confounders. What might explain the dispar- OR, 3.44; 95% CI, 1.68-7.08) reported a positive associa- ate results? In my estimation, the diversity of findings in tion of late AMD and cataract surgery. Such data are more no small part begins with differences in study design. persuasive because of the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Ophthalmology American Medical Association

Is the Risk of Incidence or Progression of Age-Related Macular Degeneration Increased After Cataract Surgery?

Klein, Barbara E. K.
JAMA Ophthalmology , Volume 127 (11) – Nov 1, 2009
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Publisher
American Medical Association
Copyright
Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6165
eISSN
2168-6173
DOI
10.1001/archophthalmol.2009.258
pmid
19901222
Publisher site
See Article on Publisher Site

Abstract

EDITORIAL Is the Risk of Incidence or Progression of Age-Related Macular Degeneration Increased After Cataract Surgery? INCE THE LATE 1980S, THERE HAVE BEEN tween cataract surgery and early or late AMD. Prevalence several reports of an association between cata- analyses from the Rotterdam Study showed no increased ract surgery and age-related macular degen- risk of wet or dry AMD in pseudophakic eyes but did re- 1-11 17 eration (AMD). Some report a cross- port increased risk of early AMD. 1,2,8 S sectional association ; some, incidence of Five-yearincidenceanalysesofpooleddatafromtheBea- 9,10 AMD after surgery ; and yet others report progression ver Dam Eye Study and the Blue Mountains Eye Study (any 4,5,10 to more severe AMD. Still, there are some studies that late AMD, odds ratio [OR], 5.7; 95% confidence interval do not find a significant association after controlling for [CI], 2.4-13.6) and the Rotterdam Study (only dry AMD, 12,13 17 relevant confounders. What might explain the dispar- OR, 3.44; 95% CI, 1.68-7.08) reported a positive associa- ate results? In my estimation, the diversity of findings in tion of late AMD and cataract surgery. Such data are more no small part begins with differences in study design. persuasive because of the

Journal

JAMA Ophthalmology – American Medical Association

Published: Nov 1, 2009

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