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Is the Pediatric End-stage Liver Disease Score Truly a Detriment to Pediatric Liver Allocation?

Is the Pediatric End-stage Liver Disease Score Truly a Detriment to Pediatric Liver Allocation? Editorial Opinion born protection and that the avoidance of the other antigens ceive Tdap during pregnancy.” Practically, if the aP vaccine in Tdap might ameliorate issues related to suppression of in- were universally available, it could be administered within the fant responses to routine vaccination. existing hepatitis B vaccine program at birth. However, aP as Finally and importantly, given the implementation of ma- a standalone vaccine is not available in the United States and ternal immunization programs in many countries, how do we many other locales and the administration of DTaP as a birth put this commendable work by Wood et al into context? As dose has been associated with significant immune interfer- outlined by the authors, the “administration of the aP vac- ence. Acellular pertussis vaccination at birth could have a role cine at birth has the potential to reduce the risk of death and in countries in which aP exists and maternal immunization pro- severe morbidity from Bordetella pertussis infection in the first grams do not. However, at this time it appears to have taken a 2 months of life among infants whose mothers who did not re- back seat to the maternal immunization approach. ARTICLE INFORMATION http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

Is the Pediatric End-stage Liver Disease Score Truly a Detriment to Pediatric Liver Allocation?

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References (15)

Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/jamapediatrics.2018.2886
Publisher site
See Article on Publisher Site

Abstract

Editorial Opinion born protection and that the avoidance of the other antigens ceive Tdap during pregnancy.” Practically, if the aP vaccine in Tdap might ameliorate issues related to suppression of in- were universally available, it could be administered within the fant responses to routine vaccination. existing hepatitis B vaccine program at birth. However, aP as Finally and importantly, given the implementation of ma- a standalone vaccine is not available in the United States and ternal immunization programs in many countries, how do we many other locales and the administration of DTaP as a birth put this commendable work by Wood et al into context? As dose has been associated with significant immune interfer- outlined by the authors, the “administration of the aP vac- ence. Acellular pertussis vaccination at birth could have a role cine at birth has the potential to reduce the risk of death and in countries in which aP exists and maternal immunization pro- severe morbidity from Bordetella pertussis infection in the first grams do not. However, at this time it appears to have taken a 2 months of life among infants whose mothers who did not re- back seat to the maternal immunization approach. ARTICLE INFORMATION

Journal

JAMA Pediatrics – American Medical Association

Published: Nov 17, 2018

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