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Is It Worthwhile to Check Colorectal Cancer in All Young Adults?

Is It Worthwhile to Check Colorectal Cancer in All Young Adults? In their cohort study of young-onset colorectal cancer (CRC), You et al1 showed that early-onset (before age 50 years) CRC is more common in patients with nonwhite ethnicity, who lack health insurance, and who live in southwestern states. The authors state that young-onset CRC is also found most often in the left-sided colon or rectosigmoid area.1 I appreciate the important results of this very large-scale study. But, there are some issues to be considered. Sporadic CRC is very rare before age 40 years. The CRC incidence rises slowly in the late forties, with most of cases of CRC occurring after age 50 years. Colorectal cancer shows the steepest increase with advanced age.2,3 Smoking, sedentary lifestyle, and diet seem to be the major risks for nonwhite persons. For these reasons, it is not clear that it is worthwhile to perform screening CRC before age 50 years. Back to top Article Information Correspondence: Dr Filik, Gastroenterology Division, Ankara Research Hospital, Ulucanlar, Altindag, Ankara 06600, Turkey (leventfilik@yahoo.co.uk). Financial Disclosure: None reported. References 1. You YN, Xing Y, Feig BW, Chang GJ, Cormier JN. Young-onset colorectal cancer: is it time to pay attention? Arch Intern Med. 2012;172(3):287-28922157065PubMedGoogle ScholarCrossref 2. Eddy DM. Screening for colorectal cancer. Ann Intern Med. 1990;113(5):373-3842200321PubMedGoogle Scholar 3. Miller AB. Trends in cancer mortality and epidemiology. Cancer. 1983;51(12):(suppl) 2413-24186850518PubMedGoogle ScholarCrossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Is It Worthwhile to Check Colorectal Cancer in All Young Adults?

Archives of Internal Medicine , Volume 172 (12) – Jun 25, 2012

Is It Worthwhile to Check Colorectal Cancer in All Young Adults?

Abstract

In their cohort study of young-onset colorectal cancer (CRC), You et al1 showed that early-onset (before age 50 years) CRC is more common in patients with nonwhite ethnicity, who lack health insurance, and who live in southwestern states. The authors state that young-onset CRC is also found most often in the left-sided colon or rectosigmoid area.1 I appreciate the important results of this very large-scale study. But, there are some issues to be considered. Sporadic CRC is very rare before...
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Publisher
American Medical Association
Copyright
Copyright © 2012 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinternmed.2012.1555
Publisher site
See Article on Publisher Site

Abstract

In their cohort study of young-onset colorectal cancer (CRC), You et al1 showed that early-onset (before age 50 years) CRC is more common in patients with nonwhite ethnicity, who lack health insurance, and who live in southwestern states. The authors state that young-onset CRC is also found most often in the left-sided colon or rectosigmoid area.1 I appreciate the important results of this very large-scale study. But, there are some issues to be considered. Sporadic CRC is very rare before age 40 years. The CRC incidence rises slowly in the late forties, with most of cases of CRC occurring after age 50 years. Colorectal cancer shows the steepest increase with advanced age.2,3 Smoking, sedentary lifestyle, and diet seem to be the major risks for nonwhite persons. For these reasons, it is not clear that it is worthwhile to perform screening CRC before age 50 years. Back to top Article Information Correspondence: Dr Filik, Gastroenterology Division, Ankara Research Hospital, Ulucanlar, Altindag, Ankara 06600, Turkey (leventfilik@yahoo.co.uk). Financial Disclosure: None reported. References 1. You YN, Xing Y, Feig BW, Chang GJ, Cormier JN. Young-onset colorectal cancer: is it time to pay attention? Arch Intern Med. 2012;172(3):287-28922157065PubMedGoogle ScholarCrossref 2. Eddy DM. Screening for colorectal cancer. Ann Intern Med. 1990;113(5):373-3842200321PubMedGoogle Scholar 3. Miller AB. Trends in cancer mortality and epidemiology. Cancer. 1983;51(12):(suppl) 2413-24186850518PubMedGoogle ScholarCrossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Jun 25, 2012

Keywords: colorectal cancer,young adult

References