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IRRITATING EFFECT OF IODIZED VEGETABLE OILS ON THE BRAIN AND SPINAL CORD WHEN DIVIDED INTO SMALL PARTICLES

IRRITATING EFFECT OF IODIZED VEGETABLE OILS ON THE BRAIN AND SPINAL CORD WHEN DIVIDED INTO SMALL... Abstract CERTAIN observations made on the unfavorable reaction to emulsions of iodized vegetable oils in the subarachnoid space of animals appear to be of fundamental importance to the neurologist and the neurosurgeon and are the basis of this report. Some years ago, in a search for a limpid or an absorbable contrast medium for use in roentgenography of the fluid-bearing spaces of the spine and cranial cavity, it occurred to me that an emulsion of one of the commonly used iodized vegetable oils might serve the purpose, since these oils had been proved, by numerous clinical tests over many years, to be relatively free from irritating properties. Frazier and Glaser1 had apparently already thought along the same line, since in 1928 they suggested the diagnostic use of iodized oil emulsions: Another thought occurred to us: If an emulsion of the oil [iodized rapeseed oil] can be prepared which will diffuse References 1. Frazier, C. H., and Glaser, M. A.: Iodized Rape-Seed Oil (Campiodol) for Cerebrospinal Visualization , J. A. M. A. 91:1609 ( (Nov. 24) ) 1928.Crossref 2. Frazer, A. C., and Walsh, V. G.: An Apparatus for the Production of Finely Dispersed Emulsions, and the Rate of Digestion of Fat by Lipase in Relation to the Surface Area , J. Physiol. 78:467, 1933. 3. Marcovich, A. W.; Walker, A. E., and Jessico, O. M.: The Immediate and Late Effects of the Intrathecal Injection of Iodized Oil , J. A. M. A. 116:2247 ( (May 17) ) 1941.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Neurology & Psychiatry American Medical Association

IRRITATING EFFECT OF IODIZED VEGETABLE OILS ON THE BRAIN AND SPINAL CORD WHEN DIVIDED INTO SMALL PARTICLES

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Publisher
American Medical Association
Copyright
Copyright © 1950 American Medical Association. All Rights Reserved.
ISSN
0096-6886
DOI
10.1001/archneurpsyc.1950.02310290111012
Publisher site
See Article on Publisher Site

Abstract

Abstract CERTAIN observations made on the unfavorable reaction to emulsions of iodized vegetable oils in the subarachnoid space of animals appear to be of fundamental importance to the neurologist and the neurosurgeon and are the basis of this report. Some years ago, in a search for a limpid or an absorbable contrast medium for use in roentgenography of the fluid-bearing spaces of the spine and cranial cavity, it occurred to me that an emulsion of one of the commonly used iodized vegetable oils might serve the purpose, since these oils had been proved, by numerous clinical tests over many years, to be relatively free from irritating properties. Frazier and Glaser1 had apparently already thought along the same line, since in 1928 they suggested the diagnostic use of iodized oil emulsions: Another thought occurred to us: If an emulsion of the oil [iodized rapeseed oil] can be prepared which will diffuse References 1. Frazier, C. H., and Glaser, M. A.: Iodized Rape-Seed Oil (Campiodol) for Cerebrospinal Visualization , J. A. M. A. 91:1609 ( (Nov. 24) ) 1928.Crossref 2. Frazer, A. C., and Walsh, V. G.: An Apparatus for the Production of Finely Dispersed Emulsions, and the Rate of Digestion of Fat by Lipase in Relation to the Surface Area , J. Physiol. 78:467, 1933. 3. Marcovich, A. W.; Walker, A. E., and Jessico, O. M.: The Immediate and Late Effects of the Intrathecal Injection of Iodized Oil , J. A. M. A. 116:2247 ( (May 17) ) 1941.Crossref

Journal

A.M.A. Archives of Neurology & PsychiatryAmerican Medical Association

Published: Nov 1, 1950

References