Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Iron Deficiency Anemia, Papilledema, Thrombocytosis, and Transient Hemiparesis

Iron Deficiency Anemia, Papilledema, Thrombocytosis, and Transient Hemiparesis Abstract The signs and symptoms found in iron deficiency anemia are nu merous and diverse, but the morbid ity is usually mild. However, several manifestations if wrongly diagnosed and incorrectly treated can lead to serious consequences. Papilledema as sociated with iron deficiency is a known but rare phenomenon which may so alarm the physician as to pro voke extensive and needless eval uations for intracranial lesions. Other associated neurological defects pre viously reported have usually been minimal but when present arouse an even higher suspicion of a space-oc cupying mass. Thrombocytosis is fre quently seen in adults with iron deficiency, but it is sufficiently unrecognized that patients may be thought to have a myeloproliferative disease with insufficient consid eration to iron as an etiological mech anism. We wish to emphasize through the following patient summary the reversible nature of these complications by the simple and oral administration of iron. References 1. Capriles L: Intracranial hypertension and iron-deficiency anemia. Arch Neurol 9:147-153, 1963Crossref 2. Greer M: Management of benign intracranial hypertension (pseudotumor cerebri). Clin Neurosurg 15:161-174, 1968 3. Davidoff LM, Dyke CG: Hypertensive meningeal hydrops. Amer J Ophthal 20:908-927, 1937 4. Watkins CH, Wagener HP, Brown RW: Cerebral symptoms accompanied by choked optic discs in types of blood dyscrasia. Amer J Ophthal 24:1374-1383, 1941 5. Dandy WE: Intracranial pressure without brain tumor. Ann Surg 106:492-513, 1937Crossref 6. Sahs AL, Joynt RJ: Brain swelling of unknown cause. Neurology 6:791-803, 1956Crossref 7. Olef I: Chlorosis. Ann Intern Med 10:1654-1663, 1937Crossref 8. Schloesser LL, Kipp MA, Wenzel FJ: Thrombocytosis in iron deficiency anemia. J Lab Clin Med 66:107-114, 1965 9. Harker LA: Current concepts: Platelet production. New Eng J Med 282:492-494, 1970Crossref 10. Mustard JF, Rowsell HC, Murphy EA: Platelet economy (platelet survival and turnover). Brit J Haemat 12:1-24, 1966.Crossref 11. Cronkite EP, Bond VP, Fliedner TM, et al: Studies on the origin, production, and destruction of platelets , in Johnson SA, Monto RW, Rebuck JW, Horn RC Jr (eds): Blood Platelets. Boston, Little Brown & Co, 1961, pp 595-609. 12. Wintrobe MM, Beebe RT: Idiopathic hypochromic anemia. Medicine 12:187-243, 1933.Crossref 13. Olivarius BF: Cerebral manifestations in thrombocythemia. Acta Psychiat Scand 32:77-82, 1957.Crossref 14. Kupfer HG, Ebbels BJ, Miller JN, et al: Essential thrombocythemia. Ann Intern Med 48:685-697, 1958.Crossref 15. Sharnoff JG: Increased pulmonary megakaryoctyes: Probable role in postoperative thromboembolism. JAMA 169:688-691, 1959.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Iron Deficiency Anemia, Papilledema, Thrombocytosis, and Transient Hemiparesis

Archives of Internal Medicine , Volume 129 (3) – Mar 1, 1972

Loading next page...
 
/lp/american-medical-association/iron-deficiency-anemia-papilledema-thrombocytosis-and-transient-D1eZ01eVNp
Publisher
American Medical Association
Copyright
Copyright © 1972 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1972.00320030103013
Publisher site
See Article on Publisher Site

Abstract

Abstract The signs and symptoms found in iron deficiency anemia are nu merous and diverse, but the morbid ity is usually mild. However, several manifestations if wrongly diagnosed and incorrectly treated can lead to serious consequences. Papilledema as sociated with iron deficiency is a known but rare phenomenon which may so alarm the physician as to pro voke extensive and needless eval uations for intracranial lesions. Other associated neurological defects pre viously reported have usually been minimal but when present arouse an even higher suspicion of a space-oc cupying mass. Thrombocytosis is fre quently seen in adults with iron deficiency, but it is sufficiently unrecognized that patients may be thought to have a myeloproliferative disease with insufficient consid eration to iron as an etiological mech anism. We wish to emphasize through the following patient summary the reversible nature of these complications by the simple and oral administration of iron. References 1. Capriles L: Intracranial hypertension and iron-deficiency anemia. Arch Neurol 9:147-153, 1963Crossref 2. Greer M: Management of benign intracranial hypertension (pseudotumor cerebri). Clin Neurosurg 15:161-174, 1968 3. Davidoff LM, Dyke CG: Hypertensive meningeal hydrops. Amer J Ophthal 20:908-927, 1937 4. Watkins CH, Wagener HP, Brown RW: Cerebral symptoms accompanied by choked optic discs in types of blood dyscrasia. Amer J Ophthal 24:1374-1383, 1941 5. Dandy WE: Intracranial pressure without brain tumor. Ann Surg 106:492-513, 1937Crossref 6. Sahs AL, Joynt RJ: Brain swelling of unknown cause. Neurology 6:791-803, 1956Crossref 7. Olef I: Chlorosis. Ann Intern Med 10:1654-1663, 1937Crossref 8. Schloesser LL, Kipp MA, Wenzel FJ: Thrombocytosis in iron deficiency anemia. J Lab Clin Med 66:107-114, 1965 9. Harker LA: Current concepts: Platelet production. New Eng J Med 282:492-494, 1970Crossref 10. Mustard JF, Rowsell HC, Murphy EA: Platelet economy (platelet survival and turnover). Brit J Haemat 12:1-24, 1966.Crossref 11. Cronkite EP, Bond VP, Fliedner TM, et al: Studies on the origin, production, and destruction of platelets , in Johnson SA, Monto RW, Rebuck JW, Horn RC Jr (eds): Blood Platelets. Boston, Little Brown & Co, 1961, pp 595-609. 12. Wintrobe MM, Beebe RT: Idiopathic hypochromic anemia. Medicine 12:187-243, 1933.Crossref 13. Olivarius BF: Cerebral manifestations in thrombocythemia. Acta Psychiat Scand 32:77-82, 1957.Crossref 14. Kupfer HG, Ebbels BJ, Miller JN, et al: Essential thrombocythemia. Ann Intern Med 48:685-697, 1958.Crossref 15. Sharnoff JG: Increased pulmonary megakaryoctyes: Probable role in postoperative thromboembolism. JAMA 169:688-691, 1959.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Mar 1, 1972

References