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INVOLUTION OF THE ADRENAL GLANDS IN NEWLY BORN INFANTS

INVOLUTION OF THE ADRENAL GLANDS IN NEWLY BORN INFANTS The imposing size of the adrenal bodies in the human fetus and in the newly born infant has long attracted the attention of anatomists. The first detailed histologic description of the involutional process whereby these glands are converted into the mature but relatively smaller organs of childhood and adult life was published by Thomas1 in 1911. In an investigation of the response of the adrenal glands during infections, Thomas called attention to the fact that these structures normally undergo extensive morphologic reorganization during the first year of life: The inner zone of the cortex (zona reticularis), which is relatively wide and conspicuously hyperemic at birth, suffers complete degeneration and is encroached on and replaced by the rapidly growing medullary portion of the gland. More exact information concerning the details of the maturation of the adrenal glands was contributed by the researches of Kern,2 Kawamura,3 Landau,4 Lewis http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

INVOLUTION OF THE ADRENAL GLANDS IN NEWLY BORN INFANTS

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Publisher
American Medical Association
Copyright
Copyright © 1936 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1936.04140040093008
Publisher site
See Article on Publisher Site

Abstract

The imposing size of the adrenal bodies in the human fetus and in the newly born infant has long attracted the attention of anatomists. The first detailed histologic description of the involutional process whereby these glands are converted into the mature but relatively smaller organs of childhood and adult life was published by Thomas1 in 1911. In an investigation of the response of the adrenal glands during infections, Thomas called attention to the fact that these structures normally undergo extensive morphologic reorganization during the first year of life: The inner zone of the cortex (zona reticularis), which is relatively wide and conspicuously hyperemic at birth, suffers complete degeneration and is encroached on and replaced by the rapidly growing medullary portion of the gland. More exact information concerning the details of the maturation of the adrenal glands was contributed by the researches of Kern,2 Kawamura,3 Landau,4 Lewis

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Oct 1, 1936

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