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Intravitreal Disappearance Rates of Four Perfluorocarbon Gases

Intravitreal Disappearance Rates of Four Perfluorocarbon Gases Abstract • The disappearance rates of bubbles from the vitreous of rabbits were measured for four perfluorocarbon gases. The decay rate for each was found to be exponential and thus independent of the volume injected. Clinical observations indicated that the disappearance of the perfluorocarbon gases in patients also follows exponential decay, but that the half-lives are three to five times longer than in rabbits. References 1. Lincoff H, Mardirossian J, Lincoff A, et al: Intravitreal longevity of three perfluorocarbon gases . Arch Ophthalmol 1980;98:1610-1611.Crossref 2. Lincoff A, Haft D, Ligget P, et al: Intravitreal expansion of perfluorocarbon bubbles . Arch Ophthalmol 1980;98:1646.Crossref 3. Lincoff A, Lincoff H, Iwamoto T, et al: Perfluoro-n-butane: A gas for a maximum duration retinal tamponade . Arch Ophthalmol 1983; 101:460-462.Crossref 4. Lincoff H, Coleman J, Kreissig I, et al: The perfluorocarbon gases in the treatment of retinal detachment . Ophthalmology 1983;90:546-551.Crossref 5. Parver L, Lincoff H: Mechanics of intraocular gas . Invest Ophthalmol Vis Sci 1978;17:77-79. 6. Moseley H, Foulds WS: The movement of xenon-133 from the vitreous to the choroid . Exp Eye Res 1982;34:169-179.Crossref 7. Prince JH, McConnell DG: Retina and optic nerve , in Prince JH (ed): The Rabbit in Eye Research . Springfield, Ill, Charles C Thomas Publisher, 1964, chap 3, p 388. 8. Yanoff M: Anatomy of the human eye , in Sheie HG, Albert DM (eds): Textbook of Ophthalmology . Philadelphia, WB Saunders Co, 1977, chap 2, p 67. 9. Kinsey VE, Reddy DVN: Chemistry and dynamics of aqueous humor , in Prince JH (ed): The Rabbit in Eye Research . Springfield, Ill, Charles C Thomas Publisher, 1964, chap 9, p 231. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Intravitreal Disappearance Rates of Four Perfluorocarbon Gases

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Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1984.01040030748037
Publisher site
See Article on Publisher Site

Abstract

Abstract • The disappearance rates of bubbles from the vitreous of rabbits were measured for four perfluorocarbon gases. The decay rate for each was found to be exponential and thus independent of the volume injected. Clinical observations indicated that the disappearance of the perfluorocarbon gases in patients also follows exponential decay, but that the half-lives are three to five times longer than in rabbits. References 1. Lincoff H, Mardirossian J, Lincoff A, et al: Intravitreal longevity of three perfluorocarbon gases . Arch Ophthalmol 1980;98:1610-1611.Crossref 2. Lincoff A, Haft D, Ligget P, et al: Intravitreal expansion of perfluorocarbon bubbles . Arch Ophthalmol 1980;98:1646.Crossref 3. Lincoff A, Lincoff H, Iwamoto T, et al: Perfluoro-n-butane: A gas for a maximum duration retinal tamponade . Arch Ophthalmol 1983; 101:460-462.Crossref 4. Lincoff H, Coleman J, Kreissig I, et al: The perfluorocarbon gases in the treatment of retinal detachment . Ophthalmology 1983;90:546-551.Crossref 5. Parver L, Lincoff H: Mechanics of intraocular gas . Invest Ophthalmol Vis Sci 1978;17:77-79. 6. Moseley H, Foulds WS: The movement of xenon-133 from the vitreous to the choroid . Exp Eye Res 1982;34:169-179.Crossref 7. Prince JH, McConnell DG: Retina and optic nerve , in Prince JH (ed): The Rabbit in Eye Research . Springfield, Ill, Charles C Thomas Publisher, 1964, chap 3, p 388. 8. Yanoff M: Anatomy of the human eye , in Sheie HG, Albert DM (eds): Textbook of Ophthalmology . Philadelphia, WB Saunders Co, 1977, chap 2, p 67. 9. Kinsey VE, Reddy DVN: Chemistry and dynamics of aqueous humor , in Prince JH (ed): The Rabbit in Eye Research . Springfield, Ill, Charles C Thomas Publisher, 1964, chap 9, p 231.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Jun 1, 1984

References