Abstract • The disappearance rates of bubbles from the vitreous of rabbits were measured for four perfluorocarbon gases. The decay rate for each was found to be exponential and thus independent of the volume injected. Clinical observations indicated that the disappearance of the perfluorocarbon gases in patients also follows exponential decay, but that the half-lives are three to five times longer than in rabbits. References 1. Lincoff H, Mardirossian J, Lincoff A, et al: Intravitreal longevity of three perfluorocarbon gases . Arch Ophthalmol 1980;98:1610-1611.Crossref 2. Lincoff A, Haft D, Ligget P, et al: Intravitreal expansion of perfluorocarbon bubbles . Arch Ophthalmol 1980;98:1646.Crossref 3. Lincoff A, Lincoff H, Iwamoto T, et al: Perfluoro-n-butane: A gas for a maximum duration retinal tamponade . Arch Ophthalmol 1983; 101:460-462.Crossref 4. Lincoff H, Coleman J, Kreissig I, et al: The perfluorocarbon gases in the treatment of retinal detachment . Ophthalmology 1983;90:546-551.Crossref 5. Parver L, Lincoff H: Mechanics of intraocular gas . Invest Ophthalmol Vis Sci 1978;17:77-79. 6. Moseley H, Foulds WS: The movement of xenon-133 from the vitreous to the choroid . Exp Eye Res 1982;34:169-179.Crossref 7. Prince JH, McConnell DG: Retina and optic nerve , in Prince JH (ed): The Rabbit in Eye Research . Springfield, Ill, Charles C Thomas Publisher, 1964, chap 3, p 388. 8. Yanoff M: Anatomy of the human eye , in Sheie HG, Albert DM (eds): Textbook of Ophthalmology . Philadelphia, WB Saunders Co, 1977, chap 2, p 67. 9. Kinsey VE, Reddy DVN: Chemistry and dynamics of aqueous humor , in Prince JH (ed): The Rabbit in Eye Research . Springfield, Ill, Charles C Thomas Publisher, 1964, chap 9, p 231.
Archives of Ophthalmology – American Medical Association
Published: Jun 1, 1984