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F. Yeomans (1933)
CARE OF ADVANCED CARCINOMA OF THE GASTRO-INTESTINAL TRACTJAMA, 101
H. Saltzstein (1934)
INTRASPINAL (SUBARACHNOID) INJECTION OF ABSOLUTE ALCOHOL: FOR THE CONTROL OF PAIN IN FAR ADVANCED MALIGNANT GROWTHSJAMA, 103
E. Stern (1934)
Relief of intractable pain by the intraspinal (subarachnoid) injection of alcoholAmerican Journal of Surgery, 25
At least 75 per cent of all women who have carcinoma of the cervix die as the result of the condition. Nearly all these women suffer severe pain during the latter part of the disease and in a large proportion of cases the pain is constantly present, both day and night, and is almost unbearable. This is due to the fact that the sensory nerves become involved in the malignant growth. There are at present three means of relieving this pain: The first and the one almost exclusively used at present is the administration of derivatives of opium, chiefly morphine. However, there are disadvantages to this form of therapy, particularly the necessity of giving constantly increasing doses as the patient's tolerance increases, the nausea and vomiting that some women experience, the idiosyncrasy of others, the excitement produced in some, and the expense for poor patients. The second method of giving
JAMA – American Medical Association
Published: Aug 10, 1935
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