Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Intraperitoneal Neomycin as a Cause of Apnea

Intraperitoneal Neomycin as a Cause of Apnea Abstract Since the discovery of neomycin by Waksman in 1949,1 this antibiotic has been found useful in the prophylaxis and treatment of intra-abdominal infections. Poth2 and others3,4 demonstrated the effectiveness and safety of neomycin sulfate used orally as an intestinal antiseptic prior to bowel surgery. More recently, intraperitoneal instillation has been advocated in the treatment of peritonitis.5,6 Neomycin has also been given as prophylaxis against the complications associated with soilage of the peritoneal cavity. Pridgen7 in 1956 and Engel et al.8 in 1957 each reported four cases of respiratory arrest associated with neomycin administered intraperitoneally. Another case is reported in the case section of the American Society of Anesthesiologists' Newsletter.9 Ferrara et al.,10 Webber,11 Middleton et al.,12 and Doremus13 reported six additional cases. At this time we are aware of 16 patients including the one presented in this paper who References 1. Waksman, S. A., and Lechevalier, H. A.: Neomycin, A New Antibiotic Active Against Streptomycin-Resistant Bacteria, Including Tuberculosis Organisms , Science 109:305-307 ( (March 25) ) 1949.Crossref 2. Poth, E. J.: Symposium on Colonic Surgery: Intestinal Antisepsis , Am. J. Surg. 88:803-806 ( (Nov.) ) 1954.Crossref 3. Davis, J. H.; Kuhn, L. R.; Shaffer, J. R., and Amspacher, W. H.: Preoperative Preparation of the Bowel with Neomycin , Surgery 35: 434-439, ( (March) ) 1954. 4. Pulaski, E. J.; Connell, J. F., Jr., and Seeley, S. F.: Sterilization of Intestinal Tract by Antibiotics and Supplemental Agents , Ann. Surg. 132: 225-234 ( (Aug.) ) 1950.Crossref 5. Schatten, W. E.: Intraperitoneal Antibiotic Administration in the Treatment of Acute Bacterial Peritonitis , Surg. Gynec. & Obst. 102:339-346 ( (March) ) 1956. 6. Green, H. G.: Intraperitoneal Neomycin in the Treatment of Acute Bacterial Peritonitis , Surg. Gynec. & Obst. 107:169-172 ( (Aug.) ) 1958. 7. Pridgen, J. E.: Respiratory Arrest Thought to Be Due to Intraperitoneal Neomycin , Surgery 40:571-574 ( (Sept.) ) 1956. 8. Engel, H. L., and Denson, J. S.: Respiratory Depression Due to Neomycin , Surgery 42:862-864 ( (Nov.) ) 1957. 9. Green, F. H.: Case Report 190 , Am. Society of Anesthesiologists Newsletter 21:38-40, 1957. 10. Ferrara, B. E., and Phillips, R. D.: Respiratory Arrest Following Administration of Intraperitoneal Neomycin , Am. Surgeon 23:710-712 ( (Aug.) ) 1957. 11. Webber, B. M.: Respiratory Arrest Following Intraperitoneal Administration of Neomycin , A.M.A. Arch. Surg. 75:174-176 ( (Aug.) ) 1957. 12. Middleton, W. H.; Morgan, D. D., and Moyers, J.: Neostigmine Therapy for Apnea Occurring after Administration of Neomycin , J.A.M.A. 165:2186-2187 ( (Dec. 28) ) 1957. 13. Doremus, W. P.: Respiratory Arrest Following Intraperitoneal Use of Neomycin , Ann. Surg. 149:546-548 ( (April) ) 1959. 14. Pittinger, C. B., and Long, J. P.: Neuromuscular Blocking Action of Neomycin Sulfate , Antibiotics & Chemother. 8:198-203 ( (April) ) 1958. 15. Greenwood, G. J.: Neomycin Ototoxicity , A.M.A. Arch. Otolaryng. 69:390-397 ( (April) ) 1959. 16. MacLean, L. D.: Renal Failure Following Administration of Intraperitoneal Neomycin , Minn. Med. 40:557-558 ( (Aug.) ) 1957. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Intraperitoneal Neomycin as a Cause of Apnea

Archives of Surgery , Volume 81 (5) – Nov 1, 1960

Loading next page...
 
/lp/american-medical-association/intraperitoneal-neomycin-as-a-cause-of-apnea-nWnQR90FuW
Publisher
American Medical Association
Copyright
Copyright © 1960 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1960.01300050160028
Publisher site
See Article on Publisher Site

Abstract

Abstract Since the discovery of neomycin by Waksman in 1949,1 this antibiotic has been found useful in the prophylaxis and treatment of intra-abdominal infections. Poth2 and others3,4 demonstrated the effectiveness and safety of neomycin sulfate used orally as an intestinal antiseptic prior to bowel surgery. More recently, intraperitoneal instillation has been advocated in the treatment of peritonitis.5,6 Neomycin has also been given as prophylaxis against the complications associated with soilage of the peritoneal cavity. Pridgen7 in 1956 and Engel et al.8 in 1957 each reported four cases of respiratory arrest associated with neomycin administered intraperitoneally. Another case is reported in the case section of the American Society of Anesthesiologists' Newsletter.9 Ferrara et al.,10 Webber,11 Middleton et al.,12 and Doremus13 reported six additional cases. At this time we are aware of 16 patients including the one presented in this paper who References 1. Waksman, S. A., and Lechevalier, H. A.: Neomycin, A New Antibiotic Active Against Streptomycin-Resistant Bacteria, Including Tuberculosis Organisms , Science 109:305-307 ( (March 25) ) 1949.Crossref 2. Poth, E. J.: Symposium on Colonic Surgery: Intestinal Antisepsis , Am. J. Surg. 88:803-806 ( (Nov.) ) 1954.Crossref 3. Davis, J. H.; Kuhn, L. R.; Shaffer, J. R., and Amspacher, W. H.: Preoperative Preparation of the Bowel with Neomycin , Surgery 35: 434-439, ( (March) ) 1954. 4. Pulaski, E. J.; Connell, J. F., Jr., and Seeley, S. F.: Sterilization of Intestinal Tract by Antibiotics and Supplemental Agents , Ann. Surg. 132: 225-234 ( (Aug.) ) 1950.Crossref 5. Schatten, W. E.: Intraperitoneal Antibiotic Administration in the Treatment of Acute Bacterial Peritonitis , Surg. Gynec. & Obst. 102:339-346 ( (March) ) 1956. 6. Green, H. G.: Intraperitoneal Neomycin in the Treatment of Acute Bacterial Peritonitis , Surg. Gynec. & Obst. 107:169-172 ( (Aug.) ) 1958. 7. Pridgen, J. E.: Respiratory Arrest Thought to Be Due to Intraperitoneal Neomycin , Surgery 40:571-574 ( (Sept.) ) 1956. 8. Engel, H. L., and Denson, J. S.: Respiratory Depression Due to Neomycin , Surgery 42:862-864 ( (Nov.) ) 1957. 9. Green, F. H.: Case Report 190 , Am. Society of Anesthesiologists Newsletter 21:38-40, 1957. 10. Ferrara, B. E., and Phillips, R. D.: Respiratory Arrest Following Administration of Intraperitoneal Neomycin , Am. Surgeon 23:710-712 ( (Aug.) ) 1957. 11. Webber, B. M.: Respiratory Arrest Following Intraperitoneal Administration of Neomycin , A.M.A. Arch. Surg. 75:174-176 ( (Aug.) ) 1957. 12. Middleton, W. H.; Morgan, D. D., and Moyers, J.: Neostigmine Therapy for Apnea Occurring after Administration of Neomycin , J.A.M.A. 165:2186-2187 ( (Dec. 28) ) 1957. 13. Doremus, W. P.: Respiratory Arrest Following Intraperitoneal Use of Neomycin , Ann. Surg. 149:546-548 ( (April) ) 1959. 14. Pittinger, C. B., and Long, J. P.: Neuromuscular Blocking Action of Neomycin Sulfate , Antibiotics & Chemother. 8:198-203 ( (April) ) 1958. 15. Greenwood, G. J.: Neomycin Ototoxicity , A.M.A. Arch. Otolaryng. 69:390-397 ( (April) ) 1959. 16. MacLean, L. D.: Renal Failure Following Administration of Intraperitoneal Neomycin , Minn. Med. 40:557-558 ( (Aug.) ) 1957.

Journal

Archives of SurgeryAmerican Medical Association

Published: Nov 1, 1960

References