Abstract A high prevalence of elevated intraocular pressures in the diabetic population is less striking in those with proliferative diabetic retinopathy than in those without proliferative changes. In both adult and juvenile groups without proliferative retinopathy, there is a significantly higher prevalence of elevated intraocular pressure after application of topical corticosteroids than in the nondiabetic population. In contrast, the distribution of corticosteroid response in the group of diabetics with proliferative retinopathy resembles more closely that in the nondiabetic volunteer population and differs significantly from that in diabetics without proliferative changes. Speculations concerning the relationship of intraocular pressure and corticosteroid responsiveness to the development of proliferative diabetic retinopathy are presented. References 1. Armstrong, J.R., et al: The Incidence of Glaucoma in Diabetes Mellitus , Amer J Ophthal 55:55, 1960. 2. Christiansson, J.: Intraocular Pressure in Diabetes Mellitus , Acta Ophthal 39:155, 1961.Crossref 3. Becker, B. in Siperstein, M.D.; Colwell, A.R., Sr.; and Meyer, K.: Small Blood Vessel Involvement in Diabetes Mellitus , Washington, DC: American Institute of Biological Sciences, 1964. 4. Hetherington, J., and Shaffer, R.N.: Glaucoma Research Conference , Amer J Ophthal 58:1065, 1964. 5. Safir, A.; Paulsen, E.P.; and Klayman, J.: Elevated Intraocular Pressure in Diabetic Children , Diabetes 13:161, 1964. 6. Becker, B.: Intraocular Pressure Response to Topical Corticosteroids , Invest Ophthal 4:198, 1965. 7. Igersheimer, J.: Intraocular Pressure and Its Relation to Retinal Extravasation , Arch Ophthal 32: 50, 1944. 8. Feron, A., and Weekers, R.: Determination du coefficient de debit de l'humeur aqueuse au moyen de la tonographie et de la suction cup chez les diabetiques , Acta Ophthal 39:308, 1961. 9. Christiansson, J.: Glaucoma Simplex in Diabetes Mellitus , Acta Ophthal 43:224, 1965. 10. Okun, E., and Cibis, P.A.: The Role of Photocoagulation in the Therapy of Proliferative Diabetic Retinopathy , Arch Ophthal 75:337, 1966. 11. Levene, R.: Tonometry and Tonography in a Group Health Population , Arch Ophthal 66:68, 1961. 12. Graff, E., and Dyson, C: Outflow Studies in Children , Arch Ophthal 74:36, 1965. 13. Becker, B., and Shaffer, R.N.: Diagnosis and Therapy of the Glaucomas , ed 2, St. Louis: C.V. Mosby Co., 1965. 14. Davis, M.D.: Vitreous Contraction in Proliferative Retinopathy , Arch Ophthal 74:741, 1965. 15. Tolentino, F.I.; Lee, P.; and Schepens, S.L.: Biomicroscopic Study of Vitreous Cavity in Diabetic Retinopathy , Arch Ophthal 75:238, 1966. 16. Gay, A.J., and Rosenbaum, A.: Retinal Artery Pressure in Asymmetric Diabetic Retinopathy , Arch Ophthal 75:758-762, 1966. 17. Yamashita, T., and Becker, B.: The Basement Membrane in the Human Diabetic Eye , Diabetes 10: 167, 1961.
Archives of Ophthalmology – American Medical Association
Published: Oct 1, 1966
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