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Intestinal Perforation Following Exchange Transfusion

Intestinal Perforation Following Exchange Transfusion Abstract An infant with Rhesus hemolytic disease developed a perforation of the cecum after two exchange transfusions. The cause is unknown, but theories include alteration of hemodynamics, leaching out of toxic substances from polyvinyl tubing, and a Shwartzman reaction. It is likely that the final common event is ischemia to the bowel wall. Necrotizing colitis is probably the underlying pathological lesion in most if not all cases. Once perforation has occurred surgical intervention is essential for survival. Early exchange transfusion, careful positioning of the cannula, and stopping if warning signs occur will reduce the incidence of this complication. References 1. Schaffer AJ: Diseases of the Newborn . Philadelphia, WB Saunders, 1960, pp 350-352. 2. Waldhausen JA, Herendeen T, King H: Necrotizing colitis of the newborn: Common cause of perforation of the colon . Surgery 54:365-372, 1963. 3. Nienhuis LI: Colon perforations in the newborn . Amer Surg 29:835-840, 1963. 4. Hermann RE: Perforation of the colon from necrotizing colitis in the newborn: Report of a survival and a new aetiologic concept . Surgery 58:436-441, 1965. 5. Corkery JJ, Dubowitz V, Lister J, et al: Colonic perforation after exchange transfusion . Brit Med J 4:345-349, 1968.Crossref 6. Orme RL'E, Eades SM: Perforation of the bowel in the newborn as a complication of exchange transfusion . Brit Med J 4:349-351, 1968.Crossref 7. Wagget J: Necrotizing enterocolitis in the newborn. Read before the British Association of Paediatric Surgeons 15th International Congress, Liverpool, England, 1968. 8. Wagget J, Scott JES: Necrotizing enterocolitis in the newborn . Z Kinder Chir 7:242-247, 1969. 9. Castor WR: Spontaneous perforation of the bowel in the newborn following exchange transfusion . Canad Med Assoc J 99:934-939, 1968. 10. Denes J, Gergely K, Leb J, et al: Necrotizing enterocolitis in premature infants . Acta Paediat Acad Sci Hung 9:237-244, 1968. 11. Rogers AF, Dunn PM: Intestinal perforation, exchange transfusion, and PVC . Lancet 2:1246, 1969.Crossref 12. Stevenson JK, Graham CB, Oliver TK, et al: Neonatal necrotizing colitis: A report of 21 cases with 14 survivors . Amer J Surg 118:260-271, 1969.Crossref 13. Friedman AB, Abellera RM, Lindsky I, et al: Perforation of the colon after exchange transfusion in the newborn . New Eng J Med 282:796-797, 1970.Crossref 14. Kerr AA: Neonatal colonic perforation after exchange transfusion: A case report . New Zeal Med J 72:18-21, 1970. 15. De Sa DJ, Mucklow ES, Gough MH: Neonatal gut infarction . J Pediat Surg 5:454-459, 1970.Crossref 16. Fonkalsrud EW, Ellis RG, Clatworthy HW: Neonatal peritonitis . J Pediat Surg 1:227-238, 1966.Crossref 17. Thomas CS, Brockman SK: Idiopathic perforation of the colon in infancy: Report of two cases and literature review . Ann Surg 165:853-858, 1966.Crossref 18. Neonatal necrotizing enterocolitis, editorial . Brit Med J 3:121-122, 1970. 19. Fetterman GH: Neonatal necrotizing enterocolitis—old pitfalls or new problem? Pediatrics 48:345-348, 1971. 20. Mizrahi A, Barlow O, Berdon W, et al: Necrotizing enterocolitis in premature infants . J Pediat 66:697-706, 1965.Crossref 21. Barrie H: Ileocolitis after exchange transfusion . Lancet 1:435, 1972.Crossref 22. Lucey JF: Colonic perforation after exchange transfusion . New Eng J Med 280:724, 1969.Crossref 23. McCandless AE: Enterocolitis following exchange transfusion . Lancet 2:762, 1971.Crossref 24. McCandless AE: Ileocolitis after exchange transfusion . Lancet 2:266-267, 1972. 25. Super M: Enterocolitis following exchange transfusion . Lancet 2:1203-1204, 1971.Crossref 26. McCandless AE: Enterocolitis following exchange transfusion . Lancet 2:1316, 1971.Crossref 27. Wilson SE, Woolley MM: Primary necrotizing enterocolitis in infants . Arch Surg 99:563-566, 1969.Crossref 28. Hey EN, Ellis MI, Walker W: Ileocolitis after exchange transfusion . Lancet 1:266, 1972.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Intestinal Perforation Following Exchange Transfusion

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Publisher
American Medical Association
Copyright
Copyright © 1972 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1972.02110130138023
Publisher site
See Article on Publisher Site

Abstract

Abstract An infant with Rhesus hemolytic disease developed a perforation of the cecum after two exchange transfusions. The cause is unknown, but theories include alteration of hemodynamics, leaching out of toxic substances from polyvinyl tubing, and a Shwartzman reaction. It is likely that the final common event is ischemia to the bowel wall. Necrotizing colitis is probably the underlying pathological lesion in most if not all cases. Once perforation has occurred surgical intervention is essential for survival. Early exchange transfusion, careful positioning of the cannula, and stopping if warning signs occur will reduce the incidence of this complication. References 1. Schaffer AJ: Diseases of the Newborn . Philadelphia, WB Saunders, 1960, pp 350-352. 2. Waldhausen JA, Herendeen T, King H: Necrotizing colitis of the newborn: Common cause of perforation of the colon . Surgery 54:365-372, 1963. 3. Nienhuis LI: Colon perforations in the newborn . Amer Surg 29:835-840, 1963. 4. Hermann RE: Perforation of the colon from necrotizing colitis in the newborn: Report of a survival and a new aetiologic concept . Surgery 58:436-441, 1965. 5. Corkery JJ, Dubowitz V, Lister J, et al: Colonic perforation after exchange transfusion . Brit Med J 4:345-349, 1968.Crossref 6. Orme RL'E, Eades SM: Perforation of the bowel in the newborn as a complication of exchange transfusion . Brit Med J 4:349-351, 1968.Crossref 7. Wagget J: Necrotizing enterocolitis in the newborn. Read before the British Association of Paediatric Surgeons 15th International Congress, Liverpool, England, 1968. 8. Wagget J, Scott JES: Necrotizing enterocolitis in the newborn . Z Kinder Chir 7:242-247, 1969. 9. Castor WR: Spontaneous perforation of the bowel in the newborn following exchange transfusion . Canad Med Assoc J 99:934-939, 1968. 10. Denes J, Gergely K, Leb J, et al: Necrotizing enterocolitis in premature infants . Acta Paediat Acad Sci Hung 9:237-244, 1968. 11. Rogers AF, Dunn PM: Intestinal perforation, exchange transfusion, and PVC . Lancet 2:1246, 1969.Crossref 12. Stevenson JK, Graham CB, Oliver TK, et al: Neonatal necrotizing colitis: A report of 21 cases with 14 survivors . Amer J Surg 118:260-271, 1969.Crossref 13. Friedman AB, Abellera RM, Lindsky I, et al: Perforation of the colon after exchange transfusion in the newborn . New Eng J Med 282:796-797, 1970.Crossref 14. Kerr AA: Neonatal colonic perforation after exchange transfusion: A case report . New Zeal Med J 72:18-21, 1970. 15. De Sa DJ, Mucklow ES, Gough MH: Neonatal gut infarction . J Pediat Surg 5:454-459, 1970.Crossref 16. Fonkalsrud EW, Ellis RG, Clatworthy HW: Neonatal peritonitis . J Pediat Surg 1:227-238, 1966.Crossref 17. Thomas CS, Brockman SK: Idiopathic perforation of the colon in infancy: Report of two cases and literature review . Ann Surg 165:853-858, 1966.Crossref 18. Neonatal necrotizing enterocolitis, editorial . Brit Med J 3:121-122, 1970. 19. Fetterman GH: Neonatal necrotizing enterocolitis—old pitfalls or new problem? Pediatrics 48:345-348, 1971. 20. Mizrahi A, Barlow O, Berdon W, et al: Necrotizing enterocolitis in premature infants . J Pediat 66:697-706, 1965.Crossref 21. Barrie H: Ileocolitis after exchange transfusion . Lancet 1:435, 1972.Crossref 22. Lucey JF: Colonic perforation after exchange transfusion . New Eng J Med 280:724, 1969.Crossref 23. McCandless AE: Enterocolitis following exchange transfusion . Lancet 2:762, 1971.Crossref 24. McCandless AE: Ileocolitis after exchange transfusion . Lancet 2:266-267, 1972. 25. Super M: Enterocolitis following exchange transfusion . Lancet 2:1203-1204, 1971.Crossref 26. McCandless AE: Enterocolitis following exchange transfusion . Lancet 2:1316, 1971.Crossref 27. Wilson SE, Woolley MM: Primary necrotizing enterocolitis in infants . Arch Surg 99:563-566, 1969.Crossref 28. Hey EN, Ellis MI, Walker W: Ileocolitis after exchange transfusion . Lancet 1:266, 1972.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Jul 1, 1972

References