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INTESTINAL OBSTRUCTION: AN EXPERIMENTAL STUDY OF THE CAUSES OF SYMPTOMS AND DEATH

INTESTINAL OBSTRUCTION: AN EXPERIMENTAL STUDY OF THE CAUSES OF SYMPTOMS AND DEATH Abstract This experimental study was undertaken for the purpose of explaining certain apparent contradictions in the deductions drawn from experimental work on the development of symptoms and the cause of death in intestinal obstruction. Although a toxin has not been demonstrated in the blood, most observers believe that symptoms and death are the result of a toxemia. The source of the toxin and its physical and chemical properties have not been agreed on, and the manner by which the toxin is taken into the body has not been made clear. Without attempting an extensive review of the literature, the views held by certain recent workers will be briefly stated. Murphy and Vincent1 (1911) from experiments on cats, believe that symptoms and death in intestinal obstruction were the result of the elaboration and absorption of a toxic substance from the obstructed intestine. The toxic substance was believed to be a non-soluble References 1. Murphy and Vincent: Boston Med. and Surg. Jour. , 1911, clxv, 684.Crossref 2. Hartwell, John A., and Hoguet, J. P.: Am. Jour. Med. Sc. , 1912, cxliii, 357Crossref 3. Experimental Obstruction in Dogs with Especial Reference to the Cause of Death and the Treatment by Large Amounts of Normal Saline Solution , The Journal A. M. A. , (July 13) , 1912, p. 82 4. Jour. Exper. Med. , 1913, xviii, 139. 5. Hartwell, John A., Hoguet, J. P., and Beekman, Fenwick : An Experimental Study of Intestinal Obstruction , The Archives Int. Med. , (May 15) , 1914, p. 701. 6. Whipple, Stone and Bernheim: Bull. Johns Hopkins Hosp. , 1912, xxiii, 159 7. Jour. Exper. Med. , 1913, xvii, 286 8. Jour. Exper. Med. , 1913, xvii, 307 9. Ann. Surg. , 1914, lix, 714. 10. Davis, D. M.: Bull. Johns Hopkins Hosp. , 1914, xxv, 33. 11. Faust: Arch. f. exper. Pathol. u. Pharmakol. , 1904, li, 248.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

INTESTINAL OBSTRUCTION: AN EXPERIMENTAL STUDY OF THE CAUSES OF SYMPTOMS AND DEATH

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Publisher
American Medical Association
Copyright
Copyright © 1915 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1915.00070210053004
Publisher site
See Article on Publisher Site

Abstract

Abstract This experimental study was undertaken for the purpose of explaining certain apparent contradictions in the deductions drawn from experimental work on the development of symptoms and the cause of death in intestinal obstruction. Although a toxin has not been demonstrated in the blood, most observers believe that symptoms and death are the result of a toxemia. The source of the toxin and its physical and chemical properties have not been agreed on, and the manner by which the toxin is taken into the body has not been made clear. Without attempting an extensive review of the literature, the views held by certain recent workers will be briefly stated. Murphy and Vincent1 (1911) from experiments on cats, believe that symptoms and death in intestinal obstruction were the result of the elaboration and absorption of a toxic substance from the obstructed intestine. The toxic substance was believed to be a non-soluble References 1. Murphy and Vincent: Boston Med. and Surg. Jour. , 1911, clxv, 684.Crossref 2. Hartwell, John A., and Hoguet, J. P.: Am. Jour. Med. Sc. , 1912, cxliii, 357Crossref 3. Experimental Obstruction in Dogs with Especial Reference to the Cause of Death and the Treatment by Large Amounts of Normal Saline Solution , The Journal A. M. A. , (July 13) , 1912, p. 82 4. Jour. Exper. Med. , 1913, xviii, 139. 5. Hartwell, John A., Hoguet, J. P., and Beekman, Fenwick : An Experimental Study of Intestinal Obstruction , The Archives Int. Med. , (May 15) , 1914, p. 701. 6. Whipple, Stone and Bernheim: Bull. Johns Hopkins Hosp. , 1912, xxiii, 159 7. Jour. Exper. Med. , 1913, xvii, 286 8. Jour. Exper. Med. , 1913, xvii, 307 9. Ann. Surg. , 1914, lix, 714. 10. Davis, D. M.: Bull. Johns Hopkins Hosp. , 1914, xxv, 33. 11. Faust: Arch. f. exper. Pathol. u. Pharmakol. , 1904, li, 248.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Mar 1, 1915

References

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