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INTERRELATION OF BILE PIGMENT AND HEMOGLOBIN

INTERRELATION OF BILE PIGMENT AND HEMOGLOBIN Until recently it was generally held that the bile pigments are formed in the liver from hemoglobin liberated on the disintegration of red blood corpuscles. Views have since been entirely changed, however, by the demonstration that cells other than those of the liver have the capacity of converting the blood pigment into bile pigment at a rapid rate.4 The theory of an extrahepatic origin of bile pigments has become firmly established in present-day physiology. Indeed, there is evidence that bile pigment is not necessarily related to the destruction of red blood cells and hemoglobin but may have its origin directly in the food intake. This conclusion, however, remains debated.5 It is not to be imagined, say the physiologists, that the destruction of blood and formation of bile occur only in certain organs. They probably take place in all organs; and in the color of a bruise there is http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

INTERRELATION OF BILE PIGMENT AND HEMOGLOBIN

JAMA , Volume 96 (16) – Apr 18, 1931

INTERRELATION OF BILE PIGMENT AND HEMOGLOBIN

Abstract


Until recently it was generally held that the bile pigments are formed in the liver from hemoglobin liberated on the disintegration of red blood corpuscles. Views have since been entirely changed, however, by the demonstration that cells other than those of the liver have the capacity of converting the blood pigment into bile pigment at a rapid rate.4 The theory of an extrahepatic origin of bile pigments has become firmly established in present-day physiology. Indeed, there is...
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Publisher
American Medical Association
Copyright
Copyright © 1931 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1931.02720420034015
Publisher site
See Article on Publisher Site

Abstract

Until recently it was generally held that the bile pigments are formed in the liver from hemoglobin liberated on the disintegration of red blood corpuscles. Views have since been entirely changed, however, by the demonstration that cells other than those of the liver have the capacity of converting the blood pigment into bile pigment at a rapid rate.4 The theory of an extrahepatic origin of bile pigments has become firmly established in present-day physiology. Indeed, there is evidence that bile pigment is not necessarily related to the destruction of red blood cells and hemoglobin but may have its origin directly in the food intake. This conclusion, however, remains debated.5 It is not to be imagined, say the physiologists, that the destruction of blood and formation of bile occur only in certain organs. They probably take place in all organs; and in the color of a bruise there is

Journal

JAMAAmerican Medical Association

Published: Apr 18, 1931

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