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Interpreting Subgroup Analyses

Interpreting Subgroup Analyses EVIDENCE-BASED JOURNAL CLUB SECTION EDITORS: DIMITRI A. CHRISTAKIS, MD, MPH; HAROLD P. LEHMANN, MD, PhD Is a School-Based Asthma Treatment Program’s Effect Modified by Secondhand Smoke Exposure? alterman et al present a randomized con- the presence of additional environmental exposures such trolled trial (RCT) of a school-based asthma as domestic pets, either of which may have affected the H treatment program in this issue of the ARCHIVES. results if the distribution were unequal between groups. The authors enrolled 184 children with asthma 3 to 7 years of age from 1 school district. Children were iden- Accounting for Subjects tified via a school health form and were eligible for en- rollment if at least mild persistent asthma was con- Children enrolled for longer than 1 month were ana- firmed and the primary care physician (PCP) agreed with lyzed in the groups to which they were randomized. The the need for daily inhaled steroids. After obtaining con- 4 subjects who participated less than 1 month, all of whom sent from the family and PCP and completing a baseline were in the intervention group, were excluded from the assessment, eligible children were randomized to the analysis owing to lack of data. This http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2004 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/archpedi.158.5.469
pmid
15123480
Publisher site
See Article on Publisher Site

Abstract

EVIDENCE-BASED JOURNAL CLUB SECTION EDITORS: DIMITRI A. CHRISTAKIS, MD, MPH; HAROLD P. LEHMANN, MD, PhD Is a School-Based Asthma Treatment Program’s Effect Modified by Secondhand Smoke Exposure? alterman et al present a randomized con- the presence of additional environmental exposures such trolled trial (RCT) of a school-based asthma as domestic pets, either of which may have affected the H treatment program in this issue of the ARCHIVES. results if the distribution were unequal between groups. The authors enrolled 184 children with asthma 3 to 7 years of age from 1 school district. Children were iden- Accounting for Subjects tified via a school health form and were eligible for en- rollment if at least mild persistent asthma was con- Children enrolled for longer than 1 month were ana- firmed and the primary care physician (PCP) agreed with lyzed in the groups to which they were randomized. The the need for daily inhaled steroids. After obtaining con- 4 subjects who participated less than 1 month, all of whom sent from the family and PCP and completing a baseline were in the intervention group, were excluded from the assessment, eligible children were randomized to the analysis owing to lack of data. This

Journal

JAMA PediatricsAmerican Medical Association

Published: May 1, 2004

References