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F. Daffos, F. Forestier, C. Kaplan, W. Cox (1988)
Prenatal diagnosis and management of bleeding disorders with fetal blood sampling.American journal of obstetrics and gynecology, 158 4
J. Rohyans, A. Miser, James Miser (1982)
Subgaleal hemorrhage in infants with hemophilia: report of two cases and review of the literature.Pediatrics, 70 2
Kasper Ck, Dietrich Sl (1985)
Comprehensive management of haemophilia.Clinics in haematology, 14
Andrew Sonis, Robert Musselman (1982)
Oral bleeding in classic hemophilia.Oral surgery, oral medicine, and oral pathology, 53 4
R. Baehner, H. Strauss (1966)
Hemophilia in the first year of life.The New England journal of medicine, 275 10
I. Franze, T. Forrest (1988)
Sonographic diagnosis of a subdural hematoma as the initial manifestation of hemophilia in a newborn.Journal of Ultrasound in Medicine, 7
Luban NLC Bray GL (1987)
Hemophilia presenting with intracranial hemorrhageAJDC, 141
D. Boone (1976)
Comprehensive Management of Hemophilia
J. Lazerson (1981)
Persistent hematoma after mouth trauma.Hospital practice, 16 10
Buchanan GR (1980)
HemophiliaPediatr Clin North Am, 27
R. Nixon, G. Brindley (1989)
Hemophilia presenting as compartment syndrome in the arm following venipuncture. A case report and review of the literature.Clinical orthopaedics and related research, 244
P. Yonker, J. Graham-Pole, P. Mehta (1985)
Presentation of hemophilia A in the newborn period.The Journal of the Florida Medical Association, 72 2
J. Tarsitano, S. Cohen (1968)
Revelation and initial diagnosis of mild hemophilia from dental findings: report of case.Journal of the American Dental Association, 76 4
B. Baty, D. Drayna, ClaireO Leonard, Raymond White (1986)
PRENATAL DIAGNOSIS OF FACTOR VIII DEFICIENCY TO HELP WITH THE MANAGEMENT OF PREGNANCY AND DELIVERYThe Lancet, 327
G. Buchanan (1986)
Coagulation disorders in the neonate.Pediatric clinics of North America, 33 1
I. Schulman (1962)
Pediatric aspects of the mild hemophilias.The Medical clinics of North America, 46
Marlar RA Montgomery RR (1985)
Newborn hemostasisClin Haematol, 14
Olson Ta, Alving Bm, Cheshier Jl, Landes Rd, Ruymann Fb (1985)
Intracerebral and subdural hemorrhage in a neonate with hemophilia A.Journal of Pediatric Hematology Oncology, 7
Abstract Objective: To examine the manner of presentation and time elapsed before diagnosis in a current population of pediatric patients with coagulopathies compared with a historically similar group presented by Baehner and Strauss in 1966. Design: Comparative retrospective patient series. Setting: A large pediatric (hemophilia) referral center in New York, NY. Population: Sixty-five male patients presented for evaluation of a presumed coagulopathy between 1974 and 1989. Nine patients were excluded for inadequate data or follow-up. Of the 56 patients included, 47 were were factor VIII deficient (32 severely affected, 15 not severely affected) and nine were factor IX deficient (six severely affected, three not severely affected). Interventions: None. Results: Severely affected neonates were diagnosed younger than 1 month significantly more often in this patient population compared with the 1966 population (68.4% vs <10%, P<.001). Patients not severely affected were also diagnosed younger than 1 month significantly more often than in 1966(50% vs 2.5%, P<.001). Workup in these groups was initiated because of either bleeding events or family history with similar frequency (48.6% vs 51.4%); historically, diagnosis had ensued primarily after bleeding events. By 1 year of age, all severely affected infants had been diagnosed in our population, a statistically significant improvement compared with the historical group (100% vs <40%, P<.001); patients not severely affected were also diagnosed more frequently (72.2% vs 15%, P<.001). Eighty-five percent of diagnoses made after 1 month of age were based on bleeding events, despite a positive family history of 28.6%. Overall, 35.7% of diagnoses resulted after a positive family history was elicited. Conclusions: In this population, diagnoses were made earlier than in the comparison group. Attention to family history and early bleeding events continues to contribute to the early diagnosis of factor deficiencies.(Arch Pediatr Adolesc Med. 1994;148:589-594) References 1. Baehner RL, Strauss HS. Hemophilia in the first year of life . N Engl J Med . 1966;275:524-528.Crossref 2. Buchanan GR. Hemophilia . Pediatr Clin North Am . 1980;27:309-326. 3. Kasper CK, Dietrich SL. Comprehensive management of hemophilia . Clin Haematol . 1985;14:489-512. 4. Schulman I. Pediatric aspects of the mild hemophilias . Med Clin North Am . 1962;46:93-105. 5. Buchanan GR. Coagulation disorders in the neonate . Pediatr Clin North Am . 1986;33:203-220. 6. Montgomery RR, Marlar RA, Gill JC. Newborn hemostasis . Clin Haematol . 1985; 14:443-460. 7. Bray GL, Luban NLC. Hemophilia presenting with intracranial hemorrhage . AJDC . 1987;141:1215-1217. 8. Franze I, Forrest TS. Sonographic diagnosis of a subdural hematoma as the initial manifestation of hemophilia in a newborn . J Ultrasound Med . 1988:7: 149-152. 9. Yonker PG, Graham-Pole J, Mehta P. Presentation of hemophilia A in the newborn period . J Fla Med Assoc . 1985;72:99-100. 10. Rohyans JA, Miser AW, Miser JS. Subgaleal hemorrhage in infants with hemophilia: report of two cases and review of the literature . Pediatrics . 1982; 70:306-307. 11. Olson TA, Alving BM, Cheshier JL, Landes RD, Ruyman FB. Intracerebral and subdural hemorrhage in a neonate with hemophilia A . Am J Pediatr Hematol Oncol . 1985;7:384-387. 12. Nixon RG, Brindley GW. Hemophilia presenting as compartment syndrome in the arm following venipuncture: a case report and review of the literature . Clin Orthop . 1989;244:176-181. 13. Tarsitano JJ, Cohen SM. Revelation and initial diagnosis of mild hemophilia from dental findings: report of case . J Am Dent Assoc . 1988;76:823-825. 14. Lazerson J. Persistent hematoma after mouth trauma . Hosp Pract (Off Ed) . 1981;16:28-29. 15. Sonis AL, Musselman RJ. Oral bleeding in classic hemophilia . Oral Surg . 1982; 53:363-366.Crossref 16. Daffos F, Forestier F, Kaplan C, Cox W. Prenatal diagnosis and management of bleeding disorders with fetal blood sampling . Am J Obstet Gynecol . 1988:158: 939-946.Crossref 17. Baty BJ, Drayna D, Leonard C, White R. Prenatal diagnosis of factor VIII deficiency to help with the management of pregnancy and delivery . Lancet . 1986; 1:207.Crossref
Archives of Pediatrics & Adolescent Medicine – American Medical Association
Published: Jun 1, 1994
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