Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Induction of Glycosuria and Hyperglycemia by Topical Corticosteroid Therapy

Induction of Glycosuria and Hyperglycemia by Topical Corticosteroid Therapy Abstract • A patient with psoriasis is described who had an abnormal response to the glucose tolerance test without other evidence of diabetes and then developed postprandial hyperglycemia and glycosuria during a period of topical administration of a corticosteroid cream, halcinonide cream 0.1%, under occlusion. A second patient with a similar glucose tolerance test result showed postprandial hyperglycemia when treated similarly with betamethasone valerate cream 0.1%. Two additional patients with mildly abnormal responses to glucose tolerance tests showed no evidence of altered glucose metabolism when treated with halcinonide cream in a similar manner. (Arch Dermatol 112:1559-1562, 1976) References 1. Scoggins RB: Decrease of urinary corticosteroids following application of fluocinolone acetonide under occlusive dressing . J Invest Dermatol 39:473, 1962.Crossref 2. March C, Kerbel G: Adrenal function after application of topical steroids under occlusive plastic film . JAMA 187:676-678, 1964.Crossref 3. Gill KA, Baxter DL: Plasma cortisol suppression by steroid creams . Arch Dermatol 89:734-740, 1964.Crossref 4. Scoggins RB, Kliman RB: Percutaneous absorption of corticosteroids . New Engl J Med 273:831-840, 1965.Crossref 5. Conn JW, Fajans SS: The prediabetic state . Am J Med 31:839-850, 1961.Crossref 6. Keipert JA, Kelly R: Temporary Cushing's syndrome from percutaneous absorption of betamethasone-17-valerate . Med J Aust 1:542-544, 1971. 7. Ortega E, Brodick KH, Segal EJ: Adrenal suppression by clobetasol propionate . Lancet 1:1200, 1975.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Induction of Glycosuria and Hyperglycemia by Topical Corticosteroid Therapy

Archives of Dermatology , Volume 112 (11) – Nov 1, 1976

Loading next page...
 
/lp/american-medical-association/induction-of-glycosuria-and-hyperglycemia-by-topical-corticosteroid-bi6EVbM40I
Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1976.01630350035009
Publisher site
See Article on Publisher Site

Abstract

Abstract • A patient with psoriasis is described who had an abnormal response to the glucose tolerance test without other evidence of diabetes and then developed postprandial hyperglycemia and glycosuria during a period of topical administration of a corticosteroid cream, halcinonide cream 0.1%, under occlusion. A second patient with a similar glucose tolerance test result showed postprandial hyperglycemia when treated similarly with betamethasone valerate cream 0.1%. Two additional patients with mildly abnormal responses to glucose tolerance tests showed no evidence of altered glucose metabolism when treated with halcinonide cream in a similar manner. (Arch Dermatol 112:1559-1562, 1976) References 1. Scoggins RB: Decrease of urinary corticosteroids following application of fluocinolone acetonide under occlusive dressing . J Invest Dermatol 39:473, 1962.Crossref 2. March C, Kerbel G: Adrenal function after application of topical steroids under occlusive plastic film . JAMA 187:676-678, 1964.Crossref 3. Gill KA, Baxter DL: Plasma cortisol suppression by steroid creams . Arch Dermatol 89:734-740, 1964.Crossref 4. Scoggins RB, Kliman RB: Percutaneous absorption of corticosteroids . New Engl J Med 273:831-840, 1965.Crossref 5. Conn JW, Fajans SS: The prediabetic state . Am J Med 31:839-850, 1961.Crossref 6. Keipert JA, Kelly R: Temporary Cushing's syndrome from percutaneous absorption of betamethasone-17-valerate . Med J Aust 1:542-544, 1971. 7. Ortega E, Brodick KH, Segal EJ: Adrenal suppression by clobetasol propionate . Lancet 1:1200, 1975.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Nov 1, 1976

References