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References (12)
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R. Schoenheimer, W. Sperry (1934)
A MICROMETHOD FOR THE DETERMINATION OF FREE AND COMBINED CHOLESTEROLJournal of Biological Chemistry, 106
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W. Sperry (1936)
CHOLESTEROL OF THE BLOOD PLASMA IN THE NEONATAL PERIODJAMA Pediatrics, 51
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J. Gamble, K. Blackfan (1920)
EVIDENCE INDICATING A SYNTHESIS OF CHOLESTEROL BY INFANTSJournal of Biological Chemistry, 42
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H. Dam (1934)
The formation of coprosterol in the intestine: The action of intestinal bacteria on cholesterol.The Biochemical journal, 28 3
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F. Fitz (1935)
THE APPLICATION TO THE COLORIMETER OF THE SCHOENHEIMER AND SPERRY METHOD FOR THE DETERMINATION OF TOTAL AND FREE CHOLESTEROLJournal of Biological Chemistry, 109
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F. Verzár, E. Mcdougall (1936)
Absorption from the intestine. -
S. Thannhauser, H. Magendantz (1938)
AN ARTICLE CONTRIBUTED TO AN ANNIVERSARY VOLUME IN HONOR OF DOCTOR JOSEPH HERSEY PRATT: THE DIFFERENT CLINICAL GROUPS OF XANTHOMATOUS DISEASES; A CLINICAL PHYSIOLOGICAL STUDY OF 22 CASESAnnals of Internal Medicine, 11
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H. Beumer (1923)
Über Cholesterin-Bilanz und Cholesterin-AnsatzZeitschrift für die gesamte experimentelle Medizin, 35
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W. Sperry
THE RELATIONSHIP BETWEEN TOTAL AND FREE CHOLESTEROL IN HUMAN BLOOD SERUMJournal of Biological Chemistry, 114
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R. Schoenheimer (1931)
NEW CONTRIBUTIONS IN STEROL METABOLISM.Science, 74 1928
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H. Dam (1934)
The formation of coprosterol in the intestine: Possible rôle of dihydrocholesterol, and a method of determining dihydrocholesterol in presence of cholesterol.The Biochemical journal, 28 3
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A. Windaus
Über die quantitative Bestimmung des Cholesterins und der Cholesterinester in einigen normalen und pathologischen Nieren.Biological Chemistry, 65
- Publisher
- American Medical Association
- Copyright
- Copyright © 1943 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
- ISSN
- 0096-8994
- eISSN
- 1538-3628
- DOI
- 10.1001/archpedi.1943.02010140043003
- Publisher site
- See Article on Publisher Site
Abstract
In reading the literature on cholesterol metabolism one is confronted with the most contradictory results. To a great extent this confusion is due to two circumstances: (1) the use of different species of animals in the investigations and (2) the inadequacy of the methods used. The latter should no longer be a source of difficulty, because accurate methods for the detection of cholesterol in tissues as well as in blood are now available. Confusion due to the first point can also be eliminated easily if consideration is given to the fact that results obtained for one animal do not necessarily hold true for an animal of a different species. So far as the cholesterol metabolism of human beings is concerned, only a few essential facts have been established. Gamble and Blackfan1 found consistently negative balances in infants, and they consequently concluded that infants can synthesize cholesterol. This important finding
Journal
American journal of diseases of children – American Medical Association
Published: Feb 1, 1943