Published Online: January 09, 2012. doi:10.1001/archinternmed.2011.1619 EDITOR’S NOTE ONLINE FIRST ARCH INTERN MED PUBLISHED ONLINE JANUARY 09, 2012 WWW.ARCHINTERNMED.COM E1 ©2012 American Medical Association. All rights reserved. Increased Diabetes Mellitus Risk With Statin Use Tipping the Balance n this issue of the Archives, Culver et al report an though observational data are potentially susceptible to association between use of statins and increased risk bias by indication, we thought it was noteworthy that the I of developing diabetes mellitus in a large cohort of increased risk of diabetes mellitus with statin use was simi- lar among women with and without a history of cardio- See also page ioi110011 vascular disease, a finding that may have important im- plications for the balance of risk and benefit of statins in women enrolled in the Women’s Health Initiative. These the setting of primary prevention in which previous meta- data confirm and extend associations previously dem- analyses show no benefit on all-cause mortality. onstrated among participants in randomized trials. Al- Kirsten L. Johansen, MD ARCH INTERN MED PUBLISHED ONLINE JANUARY 09, 2012 WWW.ARCHINTERNMED.COM E2 ©2012 American Medical Association. All rights reserved.
JAMA Internal Medicine – American Medical Association
Published: Jan 23, 2012